Excited to share our official publication @jmirpub @JMIR_HF with proof-of-concept results that #smartphone #digitalphenotyping is feasible with older adults and yields clinically useful information on risk and resilience factors for aging and #ADRD https://t.co/Z00XEi6FTX

This is great @JohnTorousMD !

#ALZFunded #AlzheimersDisease #DigitalBiomarkers #DigitalHealth

Very grateful to conduct this work within the @MountSinaiADRC with an amazing mentorship team, including Dr. Mary Sano and @FannyElahi at @IcahnMountSinai and Linda Valeri, PhD at @Columbia. Thanks also to @JohnTorousMD and @JustinBakerMD for their support to use #mindLAMP

Our goal is to inform whether passive metrics of everyday behavior via commercially available devices can be used as scalable #digitalbiomarkers of early AD. If successful, this tool may complement existing screeners to expedite treatment and/or clinical trial enrollment.

This grant - "Passive smartphone behavioral phenotypes for Alzheimer's disease screening" - seeks to identify key digital metrics from routine, everyday phone use that may flag early changes in those with elevated clinical (MCI) and biomarker (pTau217) risk of AD

Thrilled to share that I've been awarded an @alzassociation Research Fellowship (AARF) to continue my research on real-world assessment of cognition and behavior in older adults at risk for Alzheimer's disease. #ALZFunded

📣 #WEBINAR: Explore 'From Signals to Solutions: Making Digital Phenotyping Clinically Meaningful.' Join @DrAbbyOrtiz & @JohnTorousMD on August 28 to learn about bridging the gap between algorithm development and practical clinical use. Register: https://t.co/WWJdxktyMK

Well, at least the AI chatbots don't encourage teens to use cocaine! In this paper, a psychiatrist presented cases asking chatbots to validate harmful ideas - and sadly, more than one agreed. Free to read in @JMIR_JMH https://t.co/OMgThVPdI8

BREAKING: MIT just completed the first brain scan study of ChatGPT users & the results are terrifying. Turns out, AI isn't making us more productive. It's making us cognitively bankrupt. Here's what 4 months of data revealed: (hint: we've been measuring productivity all wrong)

This new review (search up to March 2023) on technology-enhanced practice competencies finds that while there is much work to be done, the vast majority of progress to date has been in the #mentalhealth space: https://t.co/xGILRyJ98z

Funding from @NIHAging was crucial in supporting this study, its investigators and our respective institutions. I'm hopeful this support will continue as there are many open questions in the use of #DHTs to solve problems in aging and AD.

Special thanks to @JohnTorousMD and his team at the @BethisraelD for developing and maintaining the open source #mindLAMP app used in this study, collaborators @UPennDBEI, and our incredible team @TempleUniv #ITS for their support.

These findings should be considered preliminary given the relatively small (N=37) sample size and limited participant heterogeneity. We believe our use of conceptually driven hypotheses (centered on overall activity level and #IIV) and open source tools increases replicability.

Encouragingly, feasibility was high in our sample - with 100% retention and positive usability/acceptability ratings. We took several steps to ensure participant comprehension and comfort and hope our practical insights can be useful to others doing this work.

We also explored various individual & contextual confounders to passive GPS data - like smartphone type/use habits, season of study participation, occupational status, and demographics. Some were more relevant than others and depend on which digital metric we examined.

Overall findings: those w/ greater activity (who travel farther, spend less time at home, visit more diverse locations) and less routine movements scored better on gold-standard cognitive & functional measures, report less depression, greater life space & community participation

@TaniaGio13 and I investigated whether daily behavior patterns of community-dwelling older adults, captured passively from personal smartphones over 4 wks, associate w/ in-person assessments. Here we focus on mobility habits via smartphone GPS (other sensor analyses forthcoming)

We all know digital literacy is a social determinant of health and a key barrier to uptake/success of digital health efforts. That is why our team has developed and is sharing our smartphone + laptop modules, slides, lessons, handouts, assessments etc: https://t.co/NgCZ1ssDQV

Thank you @NIHAging for an amazing 3 days at the #ButlerWilliams Scholars program last week packed w/ great talks, insider grant writing tips, mock study section, and new connections w/ VERY impressive (and wonderful) interdisciplinary scholars in aging science. 10/10 recommend!