Kate Wegener 🧩💊🧪
@KateWegener1
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RT @SAiGENCI: Read more about @QiZhang85's 2025 @CSL Centenary Fellowship at Look forward to seeing what you do ne….
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RT @UW: University of Washington biochemist David Baker has won the 2024 Nobel Prize in Chemistry for his pioneering work designing new pro….
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RT @AliRoennfeldt: Absolute pleasure to co-chair the @ITSASBMB special interest group session at #BMH2024 with these amazing speakers! Shou….
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RT @Tatiana_Biochem: There is still time to apply for 2 fully funded #PhD positions in my lab @UniofAdelaide in Australia. Information o….
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RT @AdelaideProtein: The Adelaide Protein Group Awards Fest is almost here! 🌟 Check out our amazing lineup of speakers and the program. Don….
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RT @Tatiana_Biochem: A few days left to apply for our fully funded #PhD scholarship to work in antimicrobial resistance @waiteresearch @Uni….
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Pink crystals for Valentine's Day! What could be better? Thanks for the wonderful news @AlixHarlington ! @fiona_whelan
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What a great group of students (and staff) to work with!.
Was great to celebrate the end of year with our fantastic University of Adelaide Master of Biotechnology (Biomedical) Students last month! Pizza (lots), games and a beautiful afternoon. Congrats to Shreetha and Araniyah who were announced as joint prizewinners.
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An honour to be recognised as a teacher alongside these wonderful people who have taught me so much over the past few years.
Congratulations to the winners of awards today at the @UofA_SET event! What a talented and dedicated group of educators! Bravo and we’ll deserved 👏👏👏 it’s an Honour to work with these legends
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RT @BronGillanders: New tenure track Lecturer/Senior Lecturer in #immunology in Biological Sciences @UniofAdelaide. #Teaching & #Research.….
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RT @BeardLabUofA: Teaching and research academic position in immunology, open at The University of Adelaide. Great opportunity to build you….
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RT @LabMuis: Phone Bacteria .How dirty is your phone? It was fun to look at the microbes present on the phone of @Amelia__Moseley from Behi….
abc.net.au
Do you take your phone to the toilet? Find out how much bacteria is living on your phone.
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RT @BellP450Chem: Congratulations to @aleciagee_ @UofA_SET on publishing her first manuscript from her PhD on engineering a #P450 #enzyme #….
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Super-chuffed to learn our paper was highlighted in Derek Lowe’s ‘In the Pipeline’ Drug Discovery blog – wonderful to hear his thoughts and so good to know he enjoyed the paper! #DrugDiscovery #Fragments @UofA_SET
science.org
Not What It Said on the Menu
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@apthompson11 So, what's the takeaway? 🤔 Remember, compounds can react and transform under your assay conditions. ⚗️ You might be measuring the activity of a completely different molecule! (🧵7/8).
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@apthompson11 Surprisingly, the hydrolysed compound turned out to be a game-changer. With a few small tweaks, we created a potent nanomolar ligand!🔬(#MedChem #StructureBasedDrugDesign #DrugDiscovery (🧵 6/8)
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@apthompson11 Detective hats went on! 🕵️♂️ After some sleuthing, we uncovered the unexpected: the original compound was hydrolysing in the crystal-soaking conditions! (Much credit here to the not-on-Twitter Birgit Gaiser for figuring out the chemistry!)💧🔍 (🧵5/8)
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And here's where it gets REALLY interesting: one compound's electron density didn't match the molecule we put in! 🤔It was a crystal-soaking enigma. 🧪 ❄️🧩(Kudos to @apthompson11 for some fantastic #ProteinCrystallography work) (🧵 4/8)
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