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KASIC.MDRO

@KASIC_MDRO

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KASIC was established to innovate and expand antimicrobial stewardship across the Commonwealth of Kentucky. All resources can be found here: https://t.co/S3fLuyiAA6

Louisville, KY
Joined April 2022
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@KASIC_MDRO
KASIC.MDRO
1 day
No Time to De-escalate. Check out this week’s KASIC pearl to learn that Even Shorter is Even Better: 3 Days for Community-acquired Pneumonia . #IDTwitter #IDXPosts #AntimicrobialResistance #antimicrobialstewardship #rxtwitter #pharmacy #FOAMed #NPs #PAs
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@KASIC_MDRO
KASIC.MDRO
2 days
Best answer: 5 days. Historically, some have considered urinary tract infections in men to be complicated and always require longer durations of therapy. However, new definitions from the IDSA include men in the definition for uncomplicated urinary tract infection. While optimal.
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@KASIC_MDRO
KASIC.MDRO
2 days
A man👱‍♂️presents with dysuria without systemic signs of infection. He is diagnosed with an uncomplicated urinary tract infection and prescribed nitrofurantoin💊. Which duration of antibiotics is best?.
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@KASIC_MDRO
KASIC.MDRO
8 days
Should Men Get More? Check out this week’s KASIC pearl to learn if in Urinary Tract Infections: Are Men Really that Complicated? @KYHealthAlerts @KYIPTraining @KYAbxAwareness @KYHospitals @KAHCF1 @KyMedDirectors @SIDPharm @UKAbxStew @Arif_Nazir_MD
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@KASIC_MDRO
KASIC.MDRO
9 days
Best answer: Yes. It is recommended to obtain cultures in patients diagnosed with CAP who are treated with empiric anti-MRSA and anti-Pseudomonal antibiotics. If cultures do not identify MRSA and/or Pseudomonas and the patient is improved, antibiotics should be de-escalated to.
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@KASIC_MDRO
KASIC.MDRO
9 days
👩‍🦳 is on cefepime, azithromycin, and vancomycin for community-acquired pneumonia 🫁. On day 3, 1500 mg azithromycin has been completed, the patient has improved 📈, and a sputum culture shows normal respiratory flora. The antibiotics are deescalated to oral amox-clav. Is this.
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@KASIC_MDRO
KASIC.MDRO
15 days
These Bugs Ain’t Hiding. Check out this week’s KASIC pearl to learn about Antibiotic De-escalation in Culture - Negative Pneumonia #IDTwitter #IDXPosts #AntimicrobialResistance #antimicrobialstewardship #rxtwitter #pharmacy #FOAMed #NPs #PAs
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@KASIC_MDRO
KASIC.MDRO
17 days
Best answer: Yes. The patient's cerobrospinal fluid analysis is not consistent with bacterial meningitis. Empiric antibiotics for suspected bacterial meningitis should be reviewed for discontinuation or de-escalation if CSF analysis and other tests are not consistent with.
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@KASIC_MDRO
KASIC.MDRO
17 days
👨‍🦰 is started on empiric antibiotics for suspected bacterial meningitis. A lumbar puncture is performed and cerebrospinal fluid (CSF) analysis reveals 0 WBC, Protein 45 mg/dL, and a CSF/plasma glucose ratio of 0.6. Additionally, no organisms are seen on Gram stain and a CSF PCR.
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@KASIC_MDRO
KASIC.MDRO
22 days
Tapping Into the Truth. Check out this week’s KASIC pearl to Understand a Cerebrospinal Fluid Analysis #IDTwitter #IDXPosts #AntimicrobialResistance #antimicrobialstewardship #rxtwitter #pharmacy #FOAMed #NPs #PAs. @KYHealthAlerts @KYIPTraining
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@KASIC_MDRO
KASIC.MDRO
23 days
Best answer: Yes. Proteus, Morganella, and Providencia spp are inherently less susceptible to imipenem through non-carbapenemase mechanisms. Cross-resistance with other carbapenems (e.g. ertapenem, meropenem) is not expected and can be used if susceptibility is demonstrated.
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@KASIC_MDRO
KASIC.MDRO
23 days
👩‍🦰 is diagnosed with a hepatic abscess. Blood cultures reveal Morganella morganii 🦠resistant to imipenem but susceptible to ertapenem. Can ertapenem be used for outpatient parenteral antibiotic therapy?. Answer/details in 🧵.
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@KASIC_MDRO
KASIC.MDRO
29 days
Imipenem Resistant but Ertapenem Susceptible? Check out this week’s KASIC pearl to learn about Proteus, Morganella, and Providencia spp: CRE or Nah? #IDTwitter #IDXPosts #AntimicrobialResistance #antimicrobialstewardship #rxtwitter #pharmacy #FOAMed #NPs
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@KASIC_MDRO
KASIC.MDRO
1 month
Best answer: No antibiotics . Infectious diarrhea is typically self-limiting and management is primarily supportive care and rehydration. Antibiotics should be specifically avoided in cases where Shiga toxin-producing E. coli is detected, as antibiotics have been associated with.
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@KASIC_MDRO
KASIC.MDRO
1 month
An otherwise healthy 🧑‍🌾 presents to the ED for dehydration from frequent 🌊💩. A GI panel is sent and the pt is discharged after receiving IV fluids. The GI panel returns positive with Shiga toxin-producing E. coli. What antibiotics should be prescribed?.
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@KASIC_MDRO
KASIC.MDRO
1 month
Dirty Details on Diarrhea. Check out this week KASIC pearl to Not Let the Bug Beat You: Diarrheagenic E. coli . #IDTwitter #IDXPosts #AntimicrobialResistance #antimicrobialstewardship #rxtwitter #pharmacy #FOAMed #NPs #PAs . @KYHealthAlerts @KYIPTraining
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@KASIC_MDRO
KASIC.MDRO
1 month
Best Answer: Yes. 2022 AAAAI/ACAAI Drug Allergy Practice Parameter states in patients WITHOUT severe delayed hypersensitivity reactions (e.g. Stevens-Johnson Syndrome, etc) to penicillins and/or cephalosporins, carbapenems can be given SAFELY. Details/references:.
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@KASIC_MDRO
KASIC.MDRO
1 month
👩 is admitted to the 🏥 with ESBL E. coli pyelonephritis. They have allergies (difficulty breathing) to TMP/SMX, ciprofloxacin, and ceftriaxone. Meropenem is ordered. Is this SAFE to give?.
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@KASIC_MDRO
KASIC.MDRO
1 month
Criss-Crossed Carbapenems. Check out this week’s KASIC Pearl to learn about Alternatives in Anaphylaxis: Carbapenems in Beta-Lactam Allergies #IDTwitter #IDXPosts #AntimicrobialResistance #antimicrobialstewardship #rxtwitter #pharmacy #FOAMed #NPs #PAs
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@KASIC_MDRO
KASIC.MDRO
2 months
Patient 1 🧑🏻 is unlikely to have a severe IgE-mediated reaction to penicillin based on their history and proceeding with penicillin as normal is likely appropriate. If they tolerate penicillin without issue, they should be de-labeled! . Details/references:
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