INTEREST Conference
            
            @INTERESTconf
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              The annual INTEREST Conference is the premier scientific conference for HIV in Africa. Join us 12-15 May 2026 in Dar es Salaam, Tanzania!
              
              Dar es Salaam, Tanzania
            
            
              
              Joined April 2016
            
            
           📌Reminder: start following us on Blue Sky!  https://t.co/2a6Kmv5JtL  We'll be migrating there after #INTEREST2025. 
          
                
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             Get to know the early-career African researchers who submitted the highest-scoring scientific abstracts to this year's INTEREST conference Patane Shilabye & Clark Brianwong explain why they study what they do + what’s next for them:  https://t.co/SSKglRF3JO 
          
          
                
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            #ThrowbackThursday Did you catch any of our presentations at @INTERESTconf 2025? If not, no worries! Explore all the impactful posters from the Pangaea Zimbabwe team here:  https://t.co/XFHqkE7qkY  Want them straight to your inbox? Sign up here:  https://t.co/ggubKjV2nc 
          
          
                
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             🎉Patane Shilabye (#SouthAfrica) & Clark Joshua Brianwong (#Uganda)🎉are the winners of the Joep Lange & Charles Boucher Awards for the highest-scoring abstracts by early-career African scientists! Selected from more than 1,700 abstracts, Patane and Clark presented their 
          
                
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             2️⃣Factors Associated with Recent Physical Violence among Orphaned and Vulnerable Children (OVC) in #Namibia Adolescents aged 15–19 years were at higher risk of experiencing violence compared to younger children aged 10–14. Children with disabilities reported lower levels of 
          
                
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             The results identify five major themes that prevent adolescents & young people (AYP) from accessing sexual and reproductive health (SRH) and HIV services: 1️⃣Socio-cultural and religious influences – This includes healthcare worker stigma, myths and misconceptions about SRH, and 
          
                
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             Mini-Oral Abstract Presentations VI, chaired by Dr Wendy Spearman (@UCT_news) & Ndeshi Nashandi 1️⃣Using Photovoice as a Community-Based Participatory Research Tool to Inform Intervention Development for Young People’s Improved Access to Sexual and Reproductive Health Services in 
          
                
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             We are at #INTEREST2025, Africa’s premier HIV science conference taking place from 13–16 May in Windhoek, Namibia. Our staff, Clark Joshua Brianwong, shared about how we are leveraging electronic case-based surveillance system (eCBSS) data for geospatial mapping of TB hotspots 
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 Take-home messages: 1️⃣CAB (cabotegravir) shows strong efficacy, but virological failure often results in cross-resistance to other integrase inhibitors (INI). 2️⃣Low drug levels are frequently observed at virological failure, although they are not an independent predictor. 3️⃣Viral
          
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 Data from the ATHENA cohort, which included 585 individuals on injectable therapy, showed a high virologic failure rate of 9%. Notably, more than 105 people initiated on cabotegravir/rilpivirine (CAB/RPV) did not meet eligibility criteria due to prior drug resistance or previous
          
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 CAB failure rate in clinical trials is extremely low: 1.6 – 2.1% Lower incidence with CAB-LA, but the proportion of breakthrough infections that are resistant is higher in men/trans women ~ Dr Annemarie Wensing
          
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 "There's tons of work ahead, particularly when our biggest donor suddenly pulled the rug from underneath us. It's an exciting time, but it's a very complicated time – and it's going to be a tragic time if we don't take the new innovations and technologies into the rightful place,
          
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 Other innovations in development include over 17 monoclonal antibodies currently under evaluation, long-acting tenofovir alafenamide (TAF), and subcutaneous formulations of TLD (tenofovir, lamivudine, and dolutegravir) ~ @FrancoisVenter3
          
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 Islatravir is a potent antiretroviral that can be administered daily, weekly, or monthly. It is well tolerated, effective at very low doses, and has a high barrier to resistance. It also holds promise for use in combination with lenacapavir as a dual therapy regimen. However,
          
          
                
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            @DTHF_SA @UCT_news @FrancoisVenter3 Lenacapavir is a capsid inhibitor that can be administered through multiple routes. It is well tolerated, has a relatively high barrier to resistance & is approved for use in individuals with extensive treatment experience.~ @FrancoisVenter3
          
          
                
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            @DTHF_SA @UCT_news Currently, there are only three long-acting injectable formulations available–cabotegravir, rilpivirine, and lenacapavir–each developed by different pharmaceutical companies and governed by distinct global access and regulatory mandates. ~ @FrancoisVenter3
          
          
                
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            @DTHF_SA @UCT_news We need to broaden our focus to include diverse populations often overlooked in research and service delivery – such as people with tuberculosis, lactating mothers, individuals with varying body mass index (BMI), those on concurrent medications, and people who use & inject drugs.
          
          
                
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             Thank you Dr.Linda Gail Bekker for such an inspiring presentation today on the importance of the prevention push needed to protect the treatment pull #INTEREST2025
          
          
                
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