Looks like threads will be expanding to Europe this December.👀.

Hi friends of #IDJClub we are exploring alternative spaces for our community to rebuild and hopefully restore the good times we had with journal club. Given the current state of affairs on X we owe to ourselves and our audience. Hope you follow us on threads.

RT @IDJClub: Thank you to everyone for coming out to our #IDWeek2023 meetup!

Thank you to everyone for coming out to our #IDWeek2023 meetup!

Please help spread the word!.

RT @febrilepodcast: See yall there, just got another batch of @febrilepodcast lanyards!.

Coming to #IDWeek2023?. Come hang out at an #IDTwitter meetup!. Wednesday Oct 11 .~8 pm til close. Westin Boston Seaport District .lobby bar. Our meetup last year 👇

Miss our #idjclub AMBITION trial Twitter Spaces or just want to hear it again? . Here’s the recording, which will be available for 30 days . Hear from @JRPerfectID @jobadd @boulware_dr @DocWoc71 @KatyGodfrey6 and more… .

Thank you everyone for a fantastic #IDJClub discussion so far. One for the ages. We (@msg_erc x @idjclub) are excited to move this discussion over to Twitter Spaces, starting at 940 EDT (in 3 minutes).

What do you anticipate would be the DOWNSIDE of using the AMBITION regimen in your patients with CM? . What more would reassure you?. #IDJClub.

What do you anticipate would be the UPSIDE of using the AMBITION trial regimen in your patients with CM?. #IDJClub.

RT @Weavofloxacin: @IDJClub This is the table that gains you acceptance in the US “healthcare” system! #IDJClub.

(And how can we assuage those concerns?) #IDJClub.

But more germane to tonight’s discussion:. What concerns do you have about generalizability to your patients?. #IDJClub.

RT @mangarone23: @boulware_dr @dralicehan @TMcCarty2010 @IDJClub Agree. I tend to minimally reduce IS. Also cultures in SOT crypto seem to….

Let's discuss. My impression: This is the largest RCT on CM to date and it was very well done. It definitively answers the Question for which it was designed (Rx of CM in PWH in Africa). Do you agree?. #IDJClub

Secondary endpoints 3/3. Significantly *fewer* Grade 3 / 4 AEs in the intervention arm (50% vs 62.3%, P<0.001). This was largely driven by anemia in the SOC arm. (Is this an adverse effect that is commonly observed in North American patients receiving AMB x 14d? 🤔). #IDJClub

Secondary endpoints 2/3. No difference in re-admissions (individual case details in Table S7, topline results shown below). Reassuring!. #IDJClub

RT @BradCutrellMD: @IDJClub Really well done trial with great f/u. Kudos to @boulware_dr and colleagues and all the study team who I am sur….