FotiadisLab
@IBMM_UniBE
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Dear colleagues, dear friends, We have moved to Bluesky: @fotiadislab.bsky.social Please follow us there!
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Our latest paper is out and we have just released an update of CryoVesNet code for automatic segmentation of synaptic vesicles https://t.co/SJpyot7B82. It now includes a Pyto wrapper to easily segment tethers and connectors. A lot of credits to @AmeeeeNeuro. #TeamTomo
github.com
segmentation of spherical vesicles in cryo-electron tomography - Zuber-group/CryoVesNet
In @JCellBiol, @AmeeeenNeuro @guiwitz @ben808080 et al. developed CryoVesNet, which enables accurate segmentation of synaptic vesicles in cryo-electron tomograms. This tool advances our understanding of synaptic function and synaptic vesicle pool dynamics. https://t.co/xOVVM0866T
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After so many years, cryo-EM has made it possible: Check out the structures of the glucose-specific PTS transporter IICB in both the inward- and outward-facing, substrate-bound states. Congratulations to Patrick Roth and collaborators for the amazing work! https://t.co/lfv1uIEk6C
nature.com
Nature Communications - Glucose is a key energy source for many organisms, efficiently transported in bacteria by specific systems. Here, the authors reveal cryo-EM structures of the glucose...
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Interested in the structural aspects of microbial rhodopsin biogenesis and retinal scavenging? Check out our latest publication! A big thank you to Stephan Hirschi and the Lemmin and Gertsch groups for the excellent collaboration. https://t.co/ge8P9zDRJx
nature.com
Nature Communications - Microbial rhodopsins are prevalent retinal-binding membrane proteins. Here, authors reveal the roles of the N-terminal signal peptide in oligomerization and of decanoate as...
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Please check out our pretty cool story in Advanced Science about the light color-controlled pH-adjustment of aqueous solutions using engineered proteoliposomes. Congrats to Daniel Harder and our collaborators in Basel, Noah Ritzmann and Daniel J. Müller. https://t.co/WDpRD72vPI
advanced.onlinelibrary.wiley.com
This proteoliposome system translates light of different colors into specific pH changes of the surrounding solution. It works with the two light-driven proton pumps bacteriorhodopsin (BR) and blue...
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The #caninedistempervirus is dangerous for #dogs & #WildAnimals, and closely related to the #measlesvirus. Researchers at #unibern have now depicted it at molecular level for the first time, thus enabling novel therapies: https://t.co/fBYHPmExT3.
@ZHAW
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Das #Staupevirus (CDV) ist gefährlich für #Hunde und #Wildtiere, und eng verwandt mit dem #Masernvirus. Forschende der #unibern konnten das CDV erstmals auf molekularer Ebene abbilden, was neue Therapieansätze ermöglicht. https://t.co/AwuON4JuzK
@ZHAW
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Finally out! Please have a look at our cryo-EM structure of the canine distemper virus (CDV) attachment glycoprotein (H protein). Amazing architecture of this morbillivirus ectodomain. https://t.co/XiZeBw3FIQ
pnas.org
Canine distemper virus (CDV) is an enveloped RNA morbillivirus that triggers respiratory, enteric, and high incidence of severe neurological disord...
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Today, 31.10.22, it is the last day of the @NCCR_TransCure! Time to say goodbye 👋 & thank you💐to @snsf_ch, @unibern and everyone who contributed to this 12 years long journey! The story continues: follow the new @LS2Switzerland section on Ion Channels & Membrane Transporters!
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#VirtualReality helping @NCCR_TransCure scientists to understand the protein structures of @seegerlab at #TransCure2022. Super grateful to Luciano Abriata from @EPFL. @snsf_ch #agora
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On Wed. next week (17 Aug. '22), the Final NCCR TransCure conference will start. Please use the #TransCure2022 hashtag on Twitter. See you at @unibern @uniofbern. Registrations are still possible until Mon. 15 Aug. 2022: https://t.co/3QJ3J7Fv87
#MembraneTransporters #IonChannels
The program of the @NCCR_TransCure Final Conference is almost complete - take a look at the great set of speakers! https://t.co/vGzBvzXEus Would you like to join us in Bern? We look forward to your registration!
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Check out our new paper describing a server for generating protein structural features to explore transcriptomics data. Congrats to 1st author @SinaiMSTP student Nicole Zatorski
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In 5 days, the Final TransCure Conference starts at @uniofbern @unibern. We are excited to welcome our colleagues from many parts of the world to discuss #MembraneTransporters #Ionchannels & #drugdiscovery. Pict.: the organizing stars @vrossett_bern Ninoska Friedli & @pateixidor
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Do you know who is the sweetest partner of the @NCCR_TransCure Final Conference? Answer: @ChocolatVillars - Swiss Chocolate You can register til Aug. 15 to this unique conference at @unibern on #MembraneTransporters #IonChannels #CryoEM #DrugDiscovery
https://t.co/vGzBvzXEus
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#SNSF70: After World War II, leading scientific organisations were convinced: Switzerland needs to catch up with international research. So, on 1 August 1952, they founded the Swiss National Science Foundation (SNSF), for which the Federal Council approved funds.
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At @IBMM_UniBern and @unibern, we are extremely glad to welcome as a new faculty Prof. Thomas Leminn and his group with strong expertise in #deeplearning and #molecularmodelling of proteins! https://t.co/6JtwRzR7ty
#phdposition and #postdocposition in #machinelearning!
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The IBMM has collected money to help a project by the Polish Ukrainian Foundation for the Development of Medicine to support newly established Kindergartens and work places for Ukrainian women who fled from the war in Ukraine to Lublin.
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Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Please check out our newest publication by Stauffer and colleagues: https://t.co/enoT2gVwpr Congratulations Mirko, Jean-Marc, Hüseyin, Zöhre and Rajendra !
nature.com
Communications Chemistry - Understanding the molecular interactions between proton-dependent oligopeptide transporters and their inhibitors is key to drug and tool development, but high-resolution...
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Are you studying #MembraneTransporters and/or #IonChannels? Join us in Bern, Switzerland, @uniofbern @NCCR_TransCure on Aug. 17-19, 2022 for cutting-edge sessions on #TransportPhysiology #CryoEM #MedChem and more https://t.co/oywtBhZbHU - Please RT
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