HanSun_lab
@HanSun_lab
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We work on drug-like molecules and characterize their interactions with proteins. #NMR #MDSimulation #cheminformatics #bioinformatics @LeibnizFMP and @TUBerlin
Berlin, Deutschland
Joined August 2015
Semisupervised Contrastive Learning for Bioactivity Prediction Using Cell Painting Image Data https://t.co/FgZFZaUGBl
@ChriSchmied @HanSun_lab @LeibnizFMP
#JCIM Vol65 Issue2 #MachineLearning #DeepLearning
pubs.acs.org
Morphological profiling has recently demonstrated remarkable potential for identifying the biological activities of small molecules. Alongside the fully supervised and self-supervised machine...
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The first paper from our @synpepbio graduate student! We assessed the performance of a high number of DFT functionals in predicting chemical shielding tensors and evaluated their impact on structure elucidation using anisotropic NMR data.
pubs.acs.org
Density functional theory (DFT) calculations have emerged as a powerful theoretical toolbox for interpreting and analyzing the experimental nuclear magnetic resonance (NMR) spectra of chemical...
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We are excited to present our DL model for bioactivity prediction using Cell Painting data. Please check out our new JCIM publication for details
Semisupervised Contrastive Learning for Bioactivity Prediction Using Cell Painting Image Data #machinelearning #compchem
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The @cecamEvents Flagship Workshop is coming to Madison, July 14-16, 2025! Hosted at @datascience_uw (thanks!), organized by @drGregBowman, @BettinaGKeller, and me (CECAM-US-CENTRAL). We have slots for contributed talks - apply here (deadline: June 11): https://t.co/y1wVEkrwGr
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Very happy and proud to see our collaborative work with Jörg Standfuss, Peter Hegemann and Igor Schapiro labs is published now in JACS: Structural Insights Into the Opening Mechanism of C1C2 Channelrhodopsin
pubs.acs.org
Channelrhodopsins, light-gated cation channels, enable precise control of neural cell depolarization or hyperpolarization with light in the field of optogenetics. This study integrates time-resolved...
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We are very grateful for this exciting opportunity provided by Leibniz Cooperative Excellence. Looking forward to new collaborations through this framework. Within this funding opportunity, we have one job opening for a PhD student or Postdoc:
Exciting news! @LeibnizFMP, @kieluni & @LeibnizLIV are starting new project, supported through "Leibniz CooperativeExcellence" program. Goal: Unravel mechanisms of K2P potassium channels – with potential new therapeutic approaches. https://t.co/1MeuAOMDXQ
#LeibnizWGL @HanSun_lab
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Congratulations! Very well deserved
I am honored to receive the 2024 Early Career @Einstein_Berlin Award together with @helenajambor for our project "PixelQuality: Best Practices for Publishing Images": https://t.co/kSnGEBboOL Thank you to our amazing team @QuarepLimi and my hosts @EuOpenscreen and @LeibnizFMP
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We have an open position for studying two-pore domain potassium channels using MD simulations and single-particle Cryo-EM. Please help us spread the word:
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📥#Job opening for a #PhD student in our group @mpi_nat in Göttingen 🇩🇪 in connection to #RTG2756 #CYTAC Job advert 🔗 https://t.co/iHtNE5QWi5 🔗 https://t.co/RKNqqTQf5U
#mircotubules #Applications welcome!
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In dieser Episode sprechen wir über Ionenkanäle, ihre Rolle im Gehirn und wie der AMPA-Rezeptor elektrische Signale steuert. 🎙️
spektrum.de
In dieser Episode sprechen wir über Ionenkanäle, ihre Rolle im Gehirn und wie der AMPA-Rezeptor elektrische Signale steuert
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In dieser Episode erklärt Dr. Sanja Bauer Mikulovic Bernd Rupp, wie die Neurobiologie der Kognition und der Emotionen funktionieren. 🎙️
spektrum.de
In dieser Episode erklärt Dr. Sanja Bauer Mikulovic Bernd Rupp, wie die Neurobiologie der Kognition und der Emotionen funktionieren und wie der Körper au…
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The new work from Lange lab @NatureComms shows how we can use SMA/DIBMA to not only see associated lipids, but can estimate their binding & study activity of intramembrane proteases in these systems through collisional mixing!
nature.com
Nature Communications - Collisional mixing of lipids in SMA or DIBMALPs has been shown recently. Here, authors show proteins in these nanoparticles also undergo mixing, allowing for study of...
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A significant milestone for our Cell Painting project. Well done, Christopher! This is the result of a collaborative effort over many years by four imaging sites at EU-OPENSCREEN. @EuOpenscreen @LeibnizFMP
Today we release the first set of #opensource Cell Painting Data generated in the @EuOpenscreen network by @LeibnizFMP, @IMTM_Olomouc, @MEDINADiscovery, @UniversidadeUSC and @imgprague. Bioactive compounds over Hep G2 and U2-OS and 4 sites. Preprint: https://t.co/jjWG76e9Te
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New insights @HanSun_lab in collaboration with the Baukrowitz lab (University of Kiel), on phosphorylation of TREK channels could offer therapeutic potential for ischemia, epilepsy & depression, published @NatureComms More: https://t.co/7q8IoPX9PP Illustration: @BarthvanRossum
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Happy to start working with new 1,2 GHz NMR spectrometer - perfect for precise analysis of complex biological systems like #proteinstructures ! Peter Schmieder, @HanSun_lab , Adam Lange, @MillesSigrid , Hartmut Oschkinat Read more 👇 https://t.co/EIx0fWmHO5
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The very best congratulations Frauke! That's great news!
Prof. Frauke Gräter @graeter_mbm joins @mpi_polymer as new Director starting July 1, 2024! 🎉 Her groundbreaking work in molecular biomechanics, simulations and machine learning promises a bright future for soft matter research. 🌟 #Research #Innovation #AI (Photo: HITS)
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@DriessLab Here's our corresponding Research Highlight article: How stable are the electrodes we design at #UniSysCat under real operating conditions? Can they compete with the ones in use for #hydrogen production? #catalysis #chemistry #sciencenews @AdvSciNews
https://t.co/10Qh1HXIRk
unisyscat.de
In a recent study, a team of UniSysCat researchers investigated the extent to which their heterostructured electrocatalysts based on non-noble metals can actually compete with noble metals when...
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Morgen ist es schon so weit: die lange Nacht der Wissenschaften 2024 erwartet euch. Und wir veranstalten ein exzellentes Science #Pubquiz an der @TUBerlin zusammen mit den 7 Exzellenzclustern aus #Berlin 👇 Kommt vorbei und rätselt mit 🧐 @LNDWBerlin
💡Alle #Quiz-Fans aufgepasst! Die Berliner #Exzellenzcluster laden zum #Science #Pubquiz ein: Im Rahmen der @LNDWBerlin wird in zwei Runden um 19 und 20:30 Uhr an der @TUBerlin gerätselt bis die Köpfe qualmen 🤯 Anmeldund vor Ort - kommt einfach vorbei, wir freuen uns auf euch!
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🔬👨🔬👩🏼🔬🧪🥼Auf dem Campus Berlin-Buch erwartet Groß und Klein ein umfangreiches Programm mit Laborführungen, Mitmachexperimenten, Kinderprogramm mit Forschungsdiplom sowie Rundgänge zur Wissenschaftsgeschichte und Campusentwicklung. @MDC_Berlin @glaeserneslabor @SilenceTheraPlc
Auf dem @campusbuch begrüßen wir euch bereits ab 16 Uhr zur Langen Nacht der Wissenschaften. 👉 Programm https://t.co/hr0Lbnadnq
#lndw24
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Many thanks to the reviewers. Again I really enjoyed the revision process and have learned a lot.
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