Douglas Walker, PhD
@HRExposomics
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PI, Comprehensive Laboratory for Untargeted Exposome Science (CLUES) | High-resolution MS to study the #exposome, #cancer and #microplastics | @emoryrollins
Emory University, Atlanta GA
Joined December 2021
Single File Injections (SFI) Enable Thousand-Sample-per-Day Analysis by Liquid Chromatography-Mass Spectrometry | ChemRxiv -
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Introducing NEXUS! A bold initiative to transform how we study the environment’s role in health. Our goal? To drive innovation to revolutionize how the biomedical and public health communities think about environmental drivers of disease @GaryWMiller3 @RimaHabre_ScD @chiragjp
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Does in-source fragmentation (ISF) account for most of the peaks in metabolomics? Our data tells a different story. Get the full breakdown and join the conversation at https://t.co/vPHdkq1aJt Kudos to @Adafede for the detailed analysis! #Metabolomics #LCMS #LCMSMS
metabolomics.blog
Detailed analysis of matching MS1 and MS2 data quantifies the contribution of in-source fragments to metabolomics data.
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Are you interested in automation and LC-HRMS to develop high-throughput analytical methods? If so, consider applying to our new position developing exposomics methods to study drug efficacy at the population scale:
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For years the #exposome has been a non-descript, fuzzy, and, at times, rather unscientific idea. Today, we can now say that exposomics represents a new science- a new way of approaching how the environment influences health. Truly a new discipline. Stay tuned for exciting news.
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Beyond thrilled to get the #NOA on a major #U01 from @NIHAging and co-lead this exciting new study with @anke_huels and Thomas Wingo. We will use cutting-edge #Exposomics and #Multiomics data to study the link between #EnvironmentalToxicants and #AlzheimersDisease and #Dementia.
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I'm recruiting #postdoc fellows! Please RT and share with anyone who may be interested and reach out if you have any questions. The fellow will primarily help with @NIEHS projects on #Exposomics, #MultiOmics, and #MaternalandChildHealth. Link to apply: https://t.co/OBWzOZaVDz
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Excited, the first batch of MS/MS from ~ 50,000 molecules. Free to download and use. 12,000 drugs -pos and neg mode. Others include Bile acids, n-acyl lipids, natural products, flavonoids etc. Good start. We will update periodically in @GNPS_UCSD.
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🚀TurboChem⚗️: A new approach for structure elucidation in non-targeted analysis Link: 👇 https://t.co/2xZqkFpNU2
#masspec #compchem #nontarget #metabolomics #HRMS #anchem #cheminformatics #nta #twitterposter #betterposter @mikemorrison @TraceyJWoodruff @PrasseLab @brueck_chris
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The deadline for the special issue "The Exposome and Human Health" in @EnvSciTech has been extended until 1st November! https://t.co/JNafrLpGIt
pubs.acs.org
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Super excited to be shortlisted as one of 12 teams using innovative approaches to address #CancerGrandChallenges. The #exposome is likely a key contributor to cancer that must be considered when evaluating #cancer risk and treatment. https://t.co/mgHRmHKJUf
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Check out Zack Jarrell's (our postdoc) discovery of phytochelatins in humans! These metal-chelating peptides are in our veggies and their functions have implications in metal toxicity. 🥕🍅
Researchers identify a #phytochelatin compound in human urine. This development may have an influence on diet, metal disposition, and bioavailability. Read more in #FASEBBioAdvances: https://t.co/kDVgHE7sXh
@EmoryCbl @EmoryMedicine
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Excited to share my latest article on single-cell exposomics! Dive into its feasibility in the Exposome special issue of @EnvSciTech edited by @PGagoFerrero! Exploring Single-Cell Exposomics by Mass Spectrometry | Environmental Science & Technology
pubs.acs.org
Single-cell exposomics, a revolutionary approach that investigates cell–environment interactions at cellular and subcellular levels, stands distinct from conventional bulk exposomics. Leveraging...
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“Even this one study should be a wakeup call — not just to new parents but to the FDA. They need to be far more proactive," @enckj told @cogcelia @WIRED #PlasticIsPoison #BreakFreeFromPlastic
https://t.co/5d2PDlwFAa
wired.com
A study of baby-food containers shows that microwaving plastic releases millions upon millions of polymer bits.
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NEW: Liang et al. conducted a state-of-the-science review examining whether high-resolution metabolomics can help clarify mechanisms of air pollution toxicity. The results were surprising—and exciting. Read our summary ➡️ https://t.co/h88sQp4irE
@donghai_liang @vrmlnroel
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Great to be back in person and spend 2 packed days on all things #exposome. #exposomebootcamp
#exposomebootcamp version 5.0 is complete. Thanks to attendees, instructors, and staff!!!@HRExposomics @XinHuPhD @austinargen @HWu17 @PollittKrystal @ColumbiaMSPH @KatherineEManz @RECETOX @YunjiaLai @EmoryCbl #exposome
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"Much as the Human Genome Project catalyzed development of genomic technologies, there is a critical need to develop a parallel Human Exposome Project that aims to develop and apply a cohesive strategy to the human exposome" Great timing as we begin the 5th #exposomebootcamp.
NEW: Liang and Walker describe the potential of nontargeted analysis as a powerful technique for comprehensively analyzing chemicals in biological samples without prior knowledge of their identity or abundance ➡️ https://t.co/FK69Vh68O6
@EmoryRollins @donghai_liang @HRExposomics
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Thrilled to team up with @HRExposomics to write this invited perspective for @EHPonline ! We described recent applications of #NonTargetedAnalysis in Characterizing the #MaternalAndChildHealth and discussed ways to realize the incredible promise of the #Exposome . @EmoryHERCULES
NEW: Liang and Walker describe the potential of nontargeted analysis as a powerful technique for comprehensively analyzing chemicals in biological samples without prior knowledge of their identity or abundance ➡️ https://t.co/FK69Vh68O6
@EmoryRollins @donghai_liang @HRExposomics
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As a serial consumer of podcasts, it was delightful to sit on the other side of the recording and talk about all things related to the #exposome, including the exciting methods we’ve been developing to learn more about how environment influences our risk for disease.
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Great to chat with @DirectorNIEHS Rick Woychik from @NIEHS on our innovative #exposome approaches to measuring #microplastics. Combining untargeted GC-and LC-HRMS will provide insight into thousands of plastic-related early-life exposures. @AuroraProjectEU
niehs.nih.gov
National Institute of Environmental Health Sciences | The mission of NIEHS is to research how the environment affects biological systems across the lifespan and to translate this knowledge to reduce...
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