1/ Last year, I lost my sister Susan to lung cancer. Lung cancer in people who never smoked is the 5th leading cause of cancer globally. It kills more people than breast, colon, and prostate cancer combined. Today at 23andMe, we’re announcing steps to accelerate breakthroughs:

The Trump administration has suspended the funding of Terence Tao and the Institute for Pure and Applied Mathematics at UCLA.

https://t.co/3htHHqmGDl

Bullish about the largest advanced manufacturing park to be built in Solano, CA!

I think Adam Back is cashing out his BTC holdings (30,000 BTC priced at a premium) by selling to the Cantor SPAC. Nothing wrong with that, but let's not sugar-coat this - an OG reducing his bag.

My first two words on this particular Sunday morning were "Hallelujah!” followed by, “Amen!” I was not in church when I uttered them. I was at my kitchen table, watching the CEO of the most valuable company in the world say precisely what mikeroweWORKS has been espousing for the

Tokenized stocks - is the endgame to sell private stocks without the burden of disclosure requirements?

Update: Spoke to veterans of the industry. TLDR = Concentrated custody risk is concerning, but there are effective mitigants to consider: * It's harder to get away with large-scale theft (fiat and stablecoin off-ramps are centralized and trace-able) * If the concern is that

(Screenshot from Matt Levine's newsletter)

Tokenized stock really just means "let's sell stock without complying with US disclosure rules" (the blockchain benefits of self custody, fractional ownership, 24-hour trading offer minor benefits and are detractors) Eg - Robinhood now selling OpenAI tokenized shares

Bitcoin related concern: How are y’all thinking about security risks of concentrated bitcoin custody? For example, Coinbase currently holds around 10% of BTC supply — compromising private keys could have similar implications as the ETH DAO hack.

Lastly, I haven’t heard of external oversight of custody services (eg Coinbase, Fidelity, Anchorage etc). I feel like some sort of regular third-party audit service would serve the industry. Thoughts?

Coinbase doesn’t inspire a lot of confidence with their recent internally-orchestrated customer data theft.

Bitcoin related concern: How are y’all thinking about security risks of concentrated bitcoin custody? For example, Coinbase currently holds around 10% of BTC supply — compromising private keys could have similar implications as the ETH DAO hack.

So Much to Say, So Little Time Sorry I’ve been scarce here of late. I’d like to tell you I’ve been “busy,” but I’m afraid the word has lost all of its meaning and relevance. Plus, it sounds like an excuse, and I prefer not to make excuses at this point in my life. Nevertheless,

This is 100% true!

Trump’s reign is vibe presidency.

DO NOT RETALIATE AND YOU WILL BE REWARDED

While everyone in business is busy losing their minds about tariffs, @zipline just quietly launched a logistics revolution in Dallas, TX. You can now get anything at a Walmart delivered to your front door by drone, with a flight time under 2 minutes for most orders.

The problem with the Gini coefficient is that it can't distinguish between Palo Alto and feudalism.