
Center for Genome Integrity
@GenomeIntegrity
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Welcome to the CGI! We are a multi-disciplinary scientific community dedicated to defining mechanisms of genome instability that impact human health
St. Louis, MO
Joined June 2021
Thank you to @SitemanCenter ,@WashUOncology ,@WashUHematology , @wusm_pathology,@WUSTLPeds, and @SLUbiochem for supporting our 4th Annual @GenomeIntegrity Retreat! A very successful event with a great group of people.
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Join us on Friday December 13, for our GMaC Seminar Series about " Regulation of MMEJ Repair" from Nausica Arnoult, PhD, from University of Colorado Boulder @ArnoultLab
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Join us on Friday September 20th, for our GMaC Seminar Series to learn more about "“When Non-Essential DNA Repair Pathways Become Essential” from Barry Sleckman,MD, PhD, from University of Alabama at Birmingham.@BarrySleckman
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Congrats the @priyanka13verma lab on their recent publication! Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCAmutant cancer cells. Check it out! .
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Congrats the @abbygreenlab for their recent publication in EMBO- The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. Check it out!
pubmed.ncbi.nlm.nih.gov
Mutational patterns caused by APOBEC3 cytidine deaminase activity are evident throughout human cancer genomes. In particular, the APOBEC3A family member is a potent genotoxin that causes substantial...
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Thank you to @SitemanCenter, @WashUOnc, @WashUHeme, @wusm_pathology, @WUSTLPeds, and @SLUbiochem for supporting our 3rd Annual @GenomeIntegrity Retreat! A very successful event with a great group of people
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