Gian Luca Di Tanna
@GLDiTanna
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Professor of Biostatistics & Health Economics ~ DEASS ~ University of Applied Sciences and Arts of Southern Switzerland ~ AS Roma and Subbuteo enthusiast
Lugano, Switzerland
Joined November 2011
Our new website is now live at https://t.co/n1Cc1Jlu9m! ๐ฅ This hub facilitates discussions on Bayesian Meta-Analysis. We're integrating codes from our book and methodological resources over the summer, structured as an interactive blog where practitioners can engage.
bayesian-ma.net
Models, code, and discussion for Bayesian meta-analysts
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In summary, this chapter reviews the foundations of statistical inference, preparing the reader for the modelling concepts central to Bayesian meta-analysis by framing inference as a process that relies on probability models, not merely on weighted averages.
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โข ๐๐ฒ๐๐ผ๐ป๐ฑ ๐๐ต๐ฒ ๐ป๐๐บ๐ฏ๐ฒ๐ฟ๐. Considerations like intention-to-treat vs per-protocol analysis (weโll soon add on the strategies as defined in the ICH E9(R1) addendum on estimands), and cautions about extrapolating to populations not represented in the studies.
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across hypothetical replications (standard error). โข ๐๐ป๐ณ๐ฒ๐ฟ๐ฒ๐ป๐ฐ๐ฒ ๐ณ๐ผ๐ฟ ๐ฐ๐ผ๐ป๐๐ถ๐ป๐๐ผ๐๐ ๐ฎ๐ป๐ฑ ๐ฏ๐ถ๐ป๐ฎ๐ฟ๐ ๐ฑ๐ฎ๐๐ฎ. From estimating a mean with the t-distribution to comparing groups, odds, odds ratios, and the logit.
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Key concepts include: โข ๐ง๐ต๐ฒ ๐ป๐ฎ๐๐๐ฟ๐ฒ ๐ผ๐ณ ๐ถ๐ป๐ณ๐ฒ๐ฟ๐ฒ๐ป๐ฐ๐ฒ. What it means to generalise beyond the data at hand. โข ๐๐ฎ๐๐ฎ ๐๐. ๐๐ฎ๐บ๐ฝ๐น๐ถ๐ป๐ด ๐ฑ๐ถ๐๐๐ฟ๐ถ๐ฏ๐๐๐ถ๐ผ๐ป๐. Why the spread of measurements (standard deviation) differs from the spread of statistics
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We revisit the key principles, terminology, and notation that underpin later chapters on Bayesian meta-analysis, making the material accessible even if you havenโt studied statistics in a while.
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๐๐ต๐ฎ๐ฝ๐๐ฒ๐ฟ ๐ญ โ ๐ ๐ฆ๐๐ฎ๐๐ถ๐๐๐ถ๐ฐ๐ฎ๐น ๐๐ป๐ณ๐ฒ๐ฟ๐ฒ๐ป๐ฐ๐ฒ ๐ฃ๐ฟ๐ถ๐บ๐ฒ๐ฟ How do we move from raw data to meaningful conclusions? Thatโs the essence of statistical inference, and the foundation we lay in the opening chapter of our book.
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Starting this week, weโll be sharing a chapter-by-chapter introduction to our book, โ๐๐ฎ๐๐ฒ๐๐ถ๐ฎ๐ป ๐ ๐ฒ๐๐ฎ-๐๐ป๐ฎ๐น๐๐๐ถ๐: ๐ ๐ฃ๐ฟ๐ฎ๐ฐ๐๐ถ๐ฐ๐ฎ๐น ๐๐ป๐๐ฟ๐ผ๐ฑ๐๐ฐ๐๐ถ๐ผ๐ปโ, available here:
routledge.com
Meta-analysis is the statistical combination of previously conducted studies, often from summary statistics but sometimes with individual participant data. It is widespread in life sciences and is...
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Call for paper on Methods for Systematic Reviews of Health Economic Evaluations, PharmacoEconomics https://t.co/Dme4tTGiGZ
#healtheconomics
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We launched a call for papers in @ph_economics on methods for Systematic Reviews of health economics evaluations
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Please reach out to with suggestions for content (papers incl. preprints, webinars, events, blog posts) that would benefit our growing community!
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We finally extended robust Bayesian meta-analysis to multilevel settings. Now, you can fit 3-level publication bias-adjusted model-averaged meta-regression models in R (and in about a week in JASP too!)
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Any #Cluster Randomised #Trial in your Meta-Analysis? I am pleased to share our latest paper in BMC Med Res Met "Warnings on the inclusion of cluster randomized trials (CRTs) in meta-analysis: results of a simulation study" https://t.co/iZYCzBAUfj
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We have tried to show its implementation across various computational frameworks including: BUGS JAGS Stan Stata JASP R packages such as bayesmeta and brms Beginning this week, I'll be sharing weekly insights from specific chapters
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This book addresses a critical methodological gap in the evidence synthesis landscape, offering a systematic approach to Bayesian meta-analytic techniques accessible to researchers across disciplines.
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I'm delighted to present the cover of the book Robert Grant and I wrote titled "Bayesian Meta-Analysis: A Practical Introduction" which will be released by CRC Press in June 2025!
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I've been really enjoying the Past, Present, Future series on revolutions, and then I was asked to be in one myself! So here I am discussing the Bayesian revolution - 250 years old and still going strong
ppfideas.com
Past Present Future is a bi-weekly History of Ideas podcast with David Runciman, host and creator of Talking Politics, exploring the history of ideas from politics to philosophy, culture to technol...
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This series on risk by Lucy Easthope seems rather good (and not just because I feature). Recommended listening
bbc.co.uk
Lucy Easthope explores the history of risk.
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We learn more from reading on paper than on screens. 54 studies, 171k people: we process print more deeply than digital contentโas long as it's informational rather than purely narrative. The paper advantage holds across ages and has grown over time. Long live physical books.
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Results of our GMRx2 trial has been published today in @TheLancet ! We showed how a novel low-dose triple single-pill combination led to clinically meaningful blood pressure reductions compared to dual combinations and was well tolerated. https://t.co/8Y0E0ji83Q
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