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Gian Luca Di Tanna Profile
Gian Luca Di Tanna

@GLDiTanna

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Professor of Biostatistics & Health Economics ~ DEASS ~ University of Applied Sciences and Arts of Southern Switzerland ~ AS Roma and Subbuteo enthusiast

Lugano, Switzerland
Joined November 2011
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@GLDiTanna
Gian Luca Di Tanna
5 months
Our new website is now live at https://t.co/n1Cc1Jlu9m! ๐Ÿ’ฅ This hub facilitates discussions on Bayesian Meta-Analysis. We're integrating codes from our book and methodological resources over the summer, structured as an interactive blog where practitioners can engage.
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bayesian-ma.net
Models, code, and discussion for Bayesian meta-analysts
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@GLDiTanna
Gian Luca Di Tanna
2 months
In summary, this chapter reviews the foundations of statistical inference, preparing the reader for the modelling concepts central to Bayesian meta-analysis by framing inference as a process that relies on probability models, not merely on weighted averages.
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@GLDiTanna
Gian Luca Di Tanna
2 months
โ€ข ๐—•๐—ฒ๐˜†๐—ผ๐—ป๐—ฑ ๐˜๐—ต๐—ฒ ๐—ป๐˜‚๐—บ๐—ฏ๐—ฒ๐—ฟ๐˜€. Considerations like intention-to-treat vs per-protocol analysis (weโ€™ll soon add on the strategies as defined in the ICH E9(R1) addendum on estimands), and cautions about extrapolating to populations not represented in the studies.
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@GLDiTanna
Gian Luca Di Tanna
2 months
across hypothetical replications (standard error). โ€ข ๐—œ๐—ป๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐—ฐ๐—ฒ ๐—ณ๐—ผ๐—ฟ ๐—ฐ๐—ผ๐—ป๐˜๐—ถ๐—ป๐˜‚๐—ผ๐˜‚๐˜€ ๐—ฎ๐—ป๐—ฑ ๐—ฏ๐—ถ๐—ป๐—ฎ๐—ฟ๐˜† ๐—ฑ๐—ฎ๐˜๐—ฎ. From estimating a mean with the t-distribution to comparing groups, odds, odds ratios, and the logit.
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@GLDiTanna
Gian Luca Di Tanna
2 months
Key concepts include: โ€ข ๐—ง๐—ต๐—ฒ ๐—ป๐—ฎ๐˜๐˜‚๐—ฟ๐—ฒ ๐—ผ๐—ณ ๐—ถ๐—ป๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐—ฐ๐—ฒ. What it means to generalise beyond the data at hand. โ€ข ๐——๐—ฎ๐˜๐—ฎ ๐˜ƒ๐˜€. ๐˜€๐—ฎ๐—บ๐—ฝ๐—น๐—ถ๐—ป๐—ด ๐—ฑ๐—ถ๐˜€๐˜๐—ฟ๐—ถ๐—ฏ๐˜‚๐˜๐—ถ๐—ผ๐—ป๐˜€. Why the spread of measurements (standard deviation) differs from the spread of statistics
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@GLDiTanna
Gian Luca Di Tanna
2 months
We revisit the key principles, terminology, and notation that underpin later chapters on Bayesian meta-analysis, making the material accessible even if you havenโ€™t studied statistics in a while.
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@GLDiTanna
Gian Luca Di Tanna
2 months
๐—–๐—ต๐—ฎ๐—ฝ๐˜๐—ฒ๐—ฟ ๐Ÿญ โ€“ ๐—” ๐—ฆ๐˜๐—ฎ๐˜๐—ถ๐˜€๐˜๐—ถ๐—ฐ๐—ฎ๐—น ๐—œ๐—ป๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐—ฐ๐—ฒ ๐—ฃ๐—ฟ๐—ถ๐—บ๐—ฒ๐—ฟ How do we move from raw data to meaningful conclusions? Thatโ€™s the essence of statistical inference, and the foundation we lay in the opening chapter of our book.
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@GLDiTanna
Gian Luca Di Tanna
2 months
Starting this week, weโ€™ll be sharing a chapter-by-chapter introduction to our book, โ€œ๐—•๐—ฎ๐˜†๐—ฒ๐˜€๐—ถ๐—ฎ๐—ป ๐— ๐—ฒ๐˜๐—ฎ-๐—”๐—ป๐—ฎ๐—น๐˜†๐˜€๐—ถ๐˜€: ๐—” ๐—ฃ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ถ๐—ฐ๐—ฎ๐—น ๐—œ๐—ป๐˜๐—ฟ๐—ผ๐—ฑ๐˜‚๐—ฐ๐˜๐—ถ๐—ผ๐—ปโ€, available here:
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routledge.com
Meta-analysis is the statistical combination of previously conducted studies, often from summary statistics but sometimes with individual participant data. It is widespread in life sciences and is...
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@Healtheconall
Healthecon-all
2 months
Call for paper on Methods for Systematic Reviews of Health Economic Evaluations, PharmacoEconomics https://t.co/Dme4tTGiGZ #healtheconomics
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@GLDiTanna
Gian Luca Di Tanna
5 months
We launched a call for papers in @ph_economics on methods for Systematic Reviews of health economics evaluations
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@GLDiTanna
Gian Luca Di Tanna
5 months
Please reach out to with suggestions for content (papers incl. preprints, webinars, events, blog posts) that would benefit our growing community!
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@BartosFra
Frantiลกek Bartoลก
5 months
We finally extended robust Bayesian meta-analysis to multilevel settings. Now, you can fit 3-level publication bias-adjusted model-averaged meta-regression models in R (and in about a week in JASP too!)
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@GLDiTanna
Gian Luca Di Tanna
7 months
Any #Cluster Randomised #Trial in your Meta-Analysis? I am pleased to share our latest paper in BMC Med Res Met "Warnings on the inclusion of cluster randomized trials (CRTs) in meta-analysis: results of a simulation study" https://t.co/iZYCzBAUfj
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@GLDiTanna
Gian Luca Di Tanna
9 months
We have tried to show its implementation across various computational frameworks including: BUGS JAGS Stan Stata JASP R packages such as bayesmeta and brms Beginning this week, I'll be sharing weekly insights from specific chapters
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@GLDiTanna
Gian Luca Di Tanna
9 months
This book addresses a critical methodological gap in the evidence synthesis landscape, offering a systematic approach to Bayesian meta-analytic techniques accessible to researchers across disciplines.
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@GLDiTanna
Gian Luca Di Tanna
9 months
I'm delighted to present the cover of the book Robert Grant and I wrote titled "Bayesian Meta-Analysis: A Practical Introduction" which will be released by CRC Press in June 2025!
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@d_spiegel
David Spiegelhalter
9 months
I've been really enjoying the Past, Present, Future series on revolutions, and then I was asked to be in one myself! So here I am discussing the Bayesian revolution - 250 years old and still going strong
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ppfideas.com
Past Present Future is a bi-weekly History of Ideas podcast with David Runciman, host and creator of Talking Politics, exploring the history of ideas from politics to philosophy, culture to technol...
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@d_spiegel
David Spiegelhalter
10 months
This series on risk by Lucy Easthope seems rather good (and not just because I feature). Recommended listening
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bbc.co.uk
Lucy Easthope explores the history of risk.
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@AdamMGrant
Adam Grant
1 year
We learn more from reading on paper than on screens. 54 studies, 171k people: we process print more deeply than digital contentโ€”as long as it's informational rather than purely narrative. The paper advantage holds across ages and has grown over time. Long live physical books.
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@GLDiTanna
Gian Luca Di Tanna
1 year
Results of our GMRx2 trial has been published today in @TheLancet ! We showed how a novel low-dose triple single-pill combination led to clinically meaningful blood pressure reductions compared to dual combinations and was well tolerated. https://t.co/8Y0E0ji83Q
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