Frontiers - Genetics
@FrontGenetics
Followers
5K
Following
626
Media
484
Statuses
16K
Research and updates from all @FrontiersIn journals in the field of genetics. #openaccess
Lausanne, Switzerland
Joined October 2011
Call for speakers Calling crop genomics researchers! Join SCE Andrew Paterson at #PAG33’s Genomics of Crop Ecosystem Services workshop. Enrol as a speaker and share your work on sustainable crop production. 🗓️ Apply by Nov 15 🔗 https://t.co/P9tdj9I1FD
0
1
1
New Research: Editorial: Advances in circRNA research: disease associations and diagnostic innovations https://t.co/pOoPcDn0gT
#FrontiersIn #Genetics
frontiersin.org
Genome-wide association studies (GWAS) have identified numerous loci for coronary artery disease (CAD), most of which lie in non-coding regions and are there...
0
0
0
New Research: Early genetic events in the colorectal carcinogenic pathway of familial adenomatous polyposis and sporadic polyp: germline and somatic alterations in carcinogenesis https://t.co/4vfiJtAinC
#FrontiersIn #Genetics
frontiersin.org
PurposeGenetic mutations in the tumor suppressor gene APC and the oncogene KRAS are an initial event in the colorectal adenoma-carcinoma sequence. Multistep ...
0
0
0
New Research: fastMETA: a fast and efficient tool for multivariate meta-analysis of GWAS https://t.co/TMBor7lYCi
#FrontiersIn #Genetics
frontiersin.org
Genome-Wide Association Studies (GWAS) have transformed human genetics by identifying thousands of loci associated with complex traits and diseases. Yet, ind...
0
0
0
New Research: Case Report: UMOD gene mutation and phenotypic overlap with REN in autosomal dominant tubulointerstitial kidney disease https://t.co/mrfKhgpPoA
#FrontiersIn #Genetics
frontiersin.org
Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a rare monogenic kidney disorder characterized by progressive tubular atrophy and interstitia...
0
0
0
New Research: rs9789446 genotype as susceptibility biomarkers for congenital hypothyroidism based on population and family validation https://t.co/pak54B1UX6
#FrontiersIn #Genetics
frontiersin.org
IntroductionCongenital hypothyroidism (CH) is a metabolic disorder in newborns due to insufficient synthesis, abnormal secretion, or defective action of thyr...
0
0
0
New Research: Expanding the spectrum of NUS1-related progressive myoclonic epilepsy: a novel variant and exploratory use of metformin https://t.co/xhgpqnh0dK
#FrontiersIn #Genetics
frontiersin.org
IntroductionProgressive myoclonic epilepsies (PME) are rare genetic disorders typically presenting with myoclonus, seizures, and cognitive decline. While sev...
0
0
0
New Research: Case Report: Minigene assays reveal a novel DNAAF6 intronic variant as the key etiology for primary ciliary dyskinesia https://t.co/tQFgOpzJbL
#FrontiersIn #Genetics
frontiersin.org
BackgroundPrimary ciliary dyskinesia (PCD), a rare hereditary disorder characterized by impaired ciliary motility, is frequently linked to infertility. Eluci...
0
0
1
New Research: Post-translational modification gene signatures implicate FBXW7 in immune and vascular dysregulation of Moyamoya disease https://t.co/scnBLPFMbc
#FrontiersIn #Genetics
frontiersin.org
BackgroundMoyamoya disease (MMD) is a rare cerebrovascular disorder characterized by progressive stenosis and occlusion of intracranial arteries and abnormal...
0
0
1
New Research: Copy number variants in fetuses with isolated and non-isolated increased nuchal translucency detected by chromosomal microarray analysis https://t.co/yfDTnRim6z
#FrontiersIn #Genetics
frontiersin.org
ObjectiveThe purpose of this study was to explore the detection rate of chromosomal copy number variants (CNVs) in fetuses with isolated and non-isolated inc...
0
0
0
New Research: Application of next-generation sequencing to determine mutations in candidate genes for congenital eye malformations in the Mexican indigenous population https://t.co/LQwq7oznZu
#FrontiersIn #Genetics
frontiersin.org
Congenital eye malformations, such as anophthalmia, microphthalmia, and coloboma, constitute a heterogeneous group of eye development defects that contribute...
0
0
0
New Research: Transcriptomic profiling of human endothelial cells infected with venezuelan equine encephalitis virus reveals NRF2 driven host reprogramming mediated by omaveloxolone treatment https://t.co/fiqm07kFJ6
#FrontiersIn #Genetics
frontiersin.org
IntroductionVenezuelan Equine Encephalitis virus (VEEV) is a mosquito-borne alphavirus that causes neurotropic disease with significant morbidity and mortali...
0
0
0
New Research: Integrative linkage and recombination analysis of 25 X-STRs across 7 linkage groups using pedigree-based and SNP-based strategies https://t.co/p3BU160pD6
#FrontiersIn #Genetics
frontiersin.org
IntroductionX-chromosomal short tandem repeats (X-STRs) are valuable genetic markers in forensic science for resolving complex kinship scenarios. However, th...
0
0
0
New Research: Editorial: Genetics (SKINOMICS): new trends in skin aging research and clinical application https://t.co/ULBfQlxdyB
#FrontiersIn #Genetics
frontiersin.org
A significant challenge in skin aging research has been the development of appropriate experimental models that accurately recapitulate human skin pathophysi...
0
0
0
New Research: Variance of Ks distribution corrects the bias in the divergence caused by the ancestral population size https://t.co/AJloQkf1Q6
#FrontiersIn #Genetics
frontiersin.org
Ks distribution, the distribution of the synonymous substitutions, has been widely used to estimate the species divergence using orthologous genes. However, ...
0
0
0
New Research: Diagnostic and prognostic value of polygene methylation detection in ascites https://t.co/EQo3CwwvkZ
#FrontiersIn #Genetics
frontiersin.org
ObjectiveTo explore a novel combination of methylation markers for the differential diagnosis of malignant ascites (MA).Materials and methodsA cohort of 164 ...
0
0
0
New Research: LRRC56 deficiency cause motile ciliopathies in humans and mice https://t.co/HCqdtCkuKK
#FrontiersIn #Genetics
frontiersin.org
IntroductionMotile ciliopathies represent a group of disorders caused by impaired motility of cilia and flagella, resulting in clinical manifestations such a...
0
0
0
New Research: Identification and validation of biomarkers related to nicotinamide metabolic pathway activity in heart failure https://t.co/v41mJ01zZt
#FrontiersIn #Genetics
frontiersin.org
BackgroundHeart failure (HF) is the final stage of cardiovascular diseases. Nicotinamide metabolism (NMN) plays a key role in cardiovascular dysfunction. We ...
0
0
0
New Research: Structural heterogeneity and functional convergence of transposable elements https://t.co/bznMNbSKDI
#FrontiersIn #Genetics
frontiersin.org
Almost half the mammalian genomes consist of transposable elements (TEs) and their derivatives. The distribution density of TEs can be associated with genomi...
0
0
0
New Research: Therapeutic applications of CRISPR-Cas9 gene editing https://t.co/0VsacfgtLB
#FrontiersIn #GenomeEditing
frontiersin.org
CRISPR-Cas9 is a gene editing tool used extensively in biological research that is now making its way into clinical therapies. With the first CRISPR therapy ...
0
0
0
New Research: Neonatal-onset familial hemophagocytic lymphohistiocytosis: a case report with genetic confirmation of PRF1 mutations https://t.co/RAnMgZXPsz
#FrontiersIn #Genetics
frontiersin.org
Familial hemophagocytic lymphohistiocytosis (FHL) is a rare, inherited immune-dysregulation syndrome that can present in the neonatal period and progress rap...
0
0
0