Flaherty Lab
@FlahertyLab
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Lab of Daniel Flaherty, Ph.D. Associate Professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University.
West Lafayette, IN
Joined August 2015
So proud of @Purdue_MCMP and @FlahertyLab grad student @molly_youse for successfully defending her PhD today! She did an amazing job and we are super excited for her next steps in her scientific career!
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Very proud of @Purdue_MCMP grad student and lab member @molly_youse for being awarded the Jenkins-Knevel Award for Outstanding Graduate Research! This is the highest honor in the Purdue COP for grad research. Very well deserved!
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RT @ACSBioMed: Design strategy from @FlahertyLab yields improved solubility for AC1 inhibitors with in vivo efficacy in rat model for infla….
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RT @nglab_malaria: Our postdoc position is still open! #malaria #ubiquitin #proteasome #protein degradation #UPR #artemisinin #resistance #….
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This project in collab with Dr. Val Watts and @Purdue_MCMP grad student @tiffany_summerr has gone from hit identification to through two manuscripts. The current scaffold had solubility liabilities and we took an approach to break up the molecular planarity to improve solubility.
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Our newest paper led by Dr. Shri Annadka presenting modifications on the pyrimidinone scaffold to improve solubility and AC1 inhibition with a new lead molecule with efficacy in a rat model for inflammatory pain.
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RT @ACSBioMed: New ethoxzolamide analogs from @FlahertyLab show improved PK properties and efficacy in mouse model for gonococcal infection….
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Our new paper from @Purdue_MCMP grad student @molly_youse is out. Molly designed new analogs of Ethoxzolamide with improved PK properties and anti-gonococcal activity leading to molecules with oral efficacy in a mouse model for N. gonorrhoeae infection.
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New paper from the lab led by @Purdue_MCMP grad student @Katrina_Holly98 in collab with Groshong lab at NIAID Rocky Mountain Laboratories. Targeting the oligopeptide transport system in B. burgdorferi.
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RT @ACSBioMed: Covalent UCHL1 inhibitor with crystal structure and anti-metastatic properties from @FlahertyLab @WendtLab_Cancer @Kesslerla….
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New paper from the lab covalently targeting UCHL1. Great collab with @WendtLab_cancer @kesslerlabox and Das Lab @ClydeDadChitta! Screening, med chem, crystallography, Ub-proteomics, cellular activity all come together to tell the story. @Purdue_MCMP .
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Purdue @Purdue_MCMP grad student @molly_youse was awarded 1st Place in the Poster Competition at the 2nd Annual Antimicrobial Resistance Conference for her work in lead opt/studying small molecule properties that affect accumulation in Neisseria gonorrhoeae! Congrats!
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I am honored to receive this title. Thank you to Chip and Jane Rutledge and to @purduepharmacy for the support!.
Chip and Jane Rutledge have a history of impactful service to Purdue. The duo shares a passion for supporting early career faculty that inspired them to endow a new professorship. Daniel Flaherty is the inaugural recipient. Full story: #pharmacysgiantleap
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Several Flaherty Lab and @Purdue_MCMP students were recognized at the @purduepharmacy Grad Student Research Day today. Congrats to Ryan Imhoff on the Jenkins-Knevel Award and Molly and Menna for poster awards! Thank you to the grad students in lab for all your contributions!
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Congrats to @Purdue_MCMP and Flaherty lab grad students @molly_youse and @Katrina_Holly98 for winning best oral presentation and best poster, respectively, at the second annual Purdue University - Notre Dame Symposium! Tons of hard work paid off. Proud of these ladies.
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Our department is hiring two positions. One in chemical biology and one in translational neuroscience. Come join a fantastic department with great colleagues!.
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RT @Purdue_MCMP: @Purdue_MCMP is hiring for Faculty Positions in Translational Neuroscience and Chemical Biology ht….
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New paper from my group and @nglab_malaria on the identification of covalent inhibitors against P. falciparum UCHL3. Keep an eye on this work in the future from our groups 😉 @Purdue_MCMP @DrugDiscoveryPU @UNMC_PathMicro .
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Our lab had 6 (!) July birthdays so we celebrated all together. Happy birthday to @Katrina_Holly98, Prabhakara, Anil, Krishna, Farman and Isaac!
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The lab got me @Cubs tickets for my birthday. Great seats and beautiful weather for a ballgame.
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