Fatima Shamsuddin
@FatimaShamsPath
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👉 67 YO male with pleural effusion. Provided are pap, DQ, cell block and IHC. What is your diagnosis?. #PathTwitter #cytology #effusion #Pathology #Pathresidents
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Set 4: Cell block with IHC from Ascitic fluid. Cell block shows three dimensional and papillaroid clusters of atypical cells with clear/vacuolated cytoplasm and pleomorphic nuclei. Background shows histiocytes and reactive mesothelial cells. BerEp4 is positive and Calretinin is
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Set 3: Pap and DQ smears from Ascitic fluid. Hypercellular smears show clusters of atypical cells with clear/vacuolated cytoplasm and pleomorphic nuclei. Background shows histiocytes and reactive mesothelial cells. #PathTwitter #gynepath #Surgpath #Pathology #Pathresidents
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Set 2: IHC on omental Bx. IHC shows positivity for CK7, PAX8, WT1, P16 (diffuse, block), P53 (mutant, overexpressed) pointing towards high grade serous carcinoma of Mullerian origin. CK20, CDX2, TTF1 were negative ruling out other primaries. #PathTwitter #gynepath #Surgpath
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A nice case of “Histo-cyto” correlation !!!. 👉 81 YO female with ascites. Set 1: Omental Bx - H&E. Showing cores of fatty tissue infiltrated by neoplastic cells in sheets, glands, nests and papillae. Focal areas of necrosis and increased mitosis present. #PathTwitter
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Answer provided here.
📣 Adrenal Adenoma – Cushing Syndrome (Pediatric Case). 👉 🧒🏼 12-year-old male with classic Cushingoid features. 📌 Gross features:.•Well-circumscribed, solitary adrenal mass.•Yellow to golden-brown cut surface.•Sharp demarcation from normal adrenal cortex. 📌 Microscopy:
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📣 Adrenal Adenoma – Cushing Syndrome (Pediatric Case). 👉 🧒🏼 12-year-old male with classic Cushingoid features. 📌 Gross features:.•Well-circumscribed, solitary adrenal mass.•Yellow to golden-brown cut surface.•Sharp demarcation from normal adrenal cortex. 📌 Microscopy:
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👉 70 YO female presenting with abdominal mass. Colonoscopy showed two large sigmoid masses. What is your diagnosis? Any further work-up/IHC?. 📣📣📣 Diagnosis: Metastatic carcinoma of Mullerian origin, favor serous carcinoma of ovary. On further work-up (CT abdomen and
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📣📣📣 Diagnosis: Metastatic carcinoma of Mullerian origin, favor serous carcinoma of ovary.
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IHC of the above case. What is your diagnosis now and what further work-up would you do?. #PathTwitter #GIpath #gynepath #pathresidents
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👉 70 YO female presenting with abdominal mass. Colonoscopy showed two large sigmoid masses. What is your diagnosis?. Any further work-up/IHC?. #PathTwitter #GIpath #Surgpath #Pathology #Pathresidents
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Details provided here.
📣📣📣 Lymphangioma circumscriptum. •A benign lymphatic malformation involving superficial and deep dermal lymphatic channels. •Clinical Appearance: Clusters of clear or pink vesicles resembling “frog spawn”; may ooze lymphatic fluid. Can be asymptomatic or associated with
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📣📣📣 Lymphangioma circumscriptum. •A benign lymphatic malformation involving superficial and deep dermal lymphatic channels. •Clinical Appearance: Clusters of clear or pink vesicles resembling “frog spawn”; may ooze lymphatic fluid. Can be asymptomatic or associated with
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👉 14 YO female presenting with lesion in right arm. Gross provided below. What is your diagnosis?. #PathTwitter #Surgpath #Pathology #Pathresidents
👉 14 YO female presenting with lesion in right arm. What are your differentials?. #PathTwitter #Surgpath #Pathology #Pathresidents
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