RT @FScholkmann: Our new paper:.𝐄𝐱𝐭𝐫𝐚-𝐦𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐀𝐓𝐏 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬, 𝐩𝐫𝐨𝐭𝐨𝐧 𝐝𝐲𝐧𝐚𝐦𝐢𝐜𝐬 𝐚𝐭 𝐭𝐡𝐞 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞 & 𝐦𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚-𝐝𝐞𝐫𝐢𝐯𝐞𝐝 𝐯𝐞𝐬𝐢𝐜𝐥𝐞𝐬: 𝐂𝐮𝐫𝐫𝐞𝐧𝐭….

PDF: #biophysics #mitochondria.

Our new paper:.𝐄𝐱𝐭𝐫𝐚-𝐦𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐀𝐓𝐏 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬, 𝐩𝐫𝐨𝐭𝐨𝐧 𝐝𝐲𝐧𝐚𝐦𝐢𝐜𝐬 𝐚𝐭 𝐭𝐡𝐞 𝐦𝐞𝐦𝐛𝐫𝐚𝐧𝐞 & 𝐦𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚-𝐝𝐞𝐫𝐢𝐯𝐞𝐝 𝐯𝐞𝐬𝐢𝐜𝐥𝐞𝐬: 𝐂𝐮𝐫𝐫𝐞𝐧𝐭 𝐟𝐢𝐧𝐝𝐢𝐧𝐠𝐬 𝐚𝐧𝐝 𝐜𝐨𝐧𝐬𝐢𝐝𝐞𝐫𝐚𝐭𝐢𝐨𝐧𝐬.@annsaada

RT @avolu_neurotech: 🚀Cedalion v25.1.0 is out! Open-source #Python toolbox for #fNIRS & #DOT with new support for #parcel-based analysis, #….

‘Luminous Links: Encounters with Light in Science, Society, and the Senses’.Nice event @ Collegium Helveticum (ETH/UZH). I gave an overview of my fNIRS research, biological autoluminescence & that intense light experiences can be encountered during altered states of consciousness

RT @FScholkmann: Lymphatic vessels can contain a vessel inside (primo vessel)!.New publication together with collea….

The glutamate/GABA-glutamine cycle: Insights, updates & advances.Nice review by J.V. Andersen. The glutamate/GABA-glutamine cycle is essential to maintain synaptic signaling & brain function

Lymphatic vessels can contain a vessel inside (primo vessel)!.New publication together with colleagues from Seoul National University. • The primo vessel is part of the primo vascular system and differs from a blood or lymph vessel.#anatomy

RT @FScholkmann: Myelin: A possible proton capacitor for energy storage during sleep & energy supply during wakefulness..

@annsaada Myelin (rich in lipids) also seems to be an oxygen buffer - see our book chapter from 2023: Myelin therefore appears to be a proton capacitor, oxygen buffer & site of extramitochondrial OSPHOS. This topic has been extensively studied by Prof. Morelli

@annsaada And in our opinion, the standard model of cellular energy metabolism also needs to be reconsidered. The new approach is: glucose metabolism is coupled to the pentose phosphate pathway & extra-mitochondrial OXPHOS (especially at the endoplasmic reticulum).

@annsaada Interestingly, sleep duration depends on white matter volume and neuronal energy consumption: there is an allometric scaling between white matter volume and sleep duration

Myelin: A possible proton capacitor for energy storage during sleep & energy supply during wakefulness.New publication together with A.M. Morelli & A. Saada (@annsaada).• A new hypothesis as to why living organisms need sleep.#neuroscience #biophysics

Fröhlich condensation (linked to coherent excitations in biomolecular systems) can be predicted at room temperature by classical Hamiltonian dynamic. Preto et al.: ". implications for energy storage, long-range selective intermolecular forces & cognition"

A map of predicted mitochondrial respiratory capacity (MRC) across the brain: Mosharov et al.: Data:

The somatic mutation theory of cancer (i.e. the prevailing paradigm that tumorigenesis is caused by cancer-driving somatic mutations & clonal expansion) is most likely incorrect. Great new paper about this insight:

Best practices for simultaneous measurement of NIRS-based cerebral and muscle oximetry during exercise.-> NIRS-based oximetry i) is a valuable tool for exercise physiology & 2) measurements are influenced by the device used & must be interpreted carefully

According to our new study, there exists a extracerebrovascular reactivity induced by changes in breathing -> Both hypocapnia & hypercapnia exert a significant impact on not only CBF but also on extracerebral tissue hemodynamics. Relevant for #fNIRS