Edward L Braun
@EdwardLBraun1
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Professor of Biology, University of Florida. Tweeting about evolution, phylogenomics, and computational biology Opinions are my own
Gainesville, FL
Joined April 2019
One of the most exciting projects of my career, years in the making. Using high-throughput precision genome editing, we mapped the fitness effects of thousands of natural variants—challenging the idea that common variants are inconsequential. https://t.co/l7cMJWikk4
biorxiv.org
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and...
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New bird paper led by the brilliant and talented Andrew Orkney! 🦆 We show that more parental care is associated with more evolutionary freedom in how birds fly.🕊️ https://t.co/IvgXMWF2td
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Proud to share a new piece in Scientific American co-authored with the brilliant Lauren Wilson, edited by @katewong, and featuring this spectacular depiction of the endless daylight of the Cretaceous summer in Alaska by Chase Stone! https://t.co/LW6c1FJUzN
scientificamerican.com
Tiny fossils hint at when birds began making their mind-blowing journey to the Arctic to breed
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Next talk: Ben Raphael (Princeton) on "Tumor Evolution over Space and Time" Monday, October 20 at 9:00 AM PDT.
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Good news! The submission deadline for RSG SE-USA's 3rd Computational Biology Symposium has been extended! If you’d like to present at the symposium, see the updated deadline and contact details on the flyer.
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The fate of horizontally acquired genes: rapid initial turnover followed by long-term persistence https://t.co/lSarVJ84Tl
#biorxiv_evobio
biorxiv.org
A major driver of bacterial evolution is horizontal gene transfer (HGT), the acquisition of genes from other strains or species. Transfers between closely related taxa are more likely to succeed,...
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Selecting a Window Size for Phylogenomic Analyses of Whole Genome Alignments using AIC https://t.co/AtsguaNGSi
@systbiol
academic.oup.com
Abstract. Gene tree discordance along a set of aligned genomes presents a challenge for phylogenomic methods to identify the non-recombining regions and re
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I’ve always been interested in the stories behind BioNumbers. Textbooks say DNA polymerase, for example, replicates 220 nucleotides per second. But how do we know this? How can one actually measure the speed of a single enzyme? A fast typist, for comparison, types ~80 words per
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In 1965, Margaret Dayhoff published the Atlas of Protein Sequence and Structure, which collated the 65 proteins whose amino acid sequences were then known. Inspired by that Atlas, today we are releasing the Dayhoff Atlas of protein sequence data and protein language models.
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📍 If you’re not an ISCB member, you can register for access to ISCB Nucleus by visiting this link:
iscb.swoogo.com
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Upcoming ISCBacademy webinar, Friday, May 2 at 11am EDT: Billera-Holmes-Vogtmann (BHV) Phylogenetic Tree Space: Algorithms and Applications to Evolutionary Biology Join the webinar by logging in to ISCB Nucleus here: https://t.co/SZhQIU7iAD
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Imagine standing in front of experts, sharing your research, and making an impact. Make it a reality—submit your abstract for ISMB/ECCB 2025 by April 17!
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The #ELIXIR3DBioInfoCommunity meeting will take place in March 2025 at the @BSC_CNS as part of a joint event with @3DSIG_ISCB. Still some days to submit abstracts for talks/posters related to #structuralbioinformatics More info: https://t.co/PLzVmVKAig
ELIXIR 3DBioinfo Annual General Meeting | ISCB 3DSig 2025 🧬💻BSC hosts this meeting that brings together structural bioinformatics researchers from 2 communities, 3D-BioInfo & 3D-SIG, for networking & to exchange ideas 📆Deadlines: Abstracts for talks: 20/01 Abstracts for
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Take flight with this landmark 2014 Nature paper by the @B10K_Project. Using 363 bird genomes from 92% of avian families, it builds a taxon-rich backbone tree for future comparative studies. A must-read for the holidays : https://t.co/JtP5IJM1SE
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🎉 The 14th ISCB #Wikipedia Competition is here! Students and postdocs are invited to create or improve Wiki articles on #ComputationalBiology and ISCB core topics. 🧬 🏆 Prizes include cash awards and a 1-year ISCB membership! 📅 Deadline: May 2, 2025 🔗
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EvolCompGen presents: Megan Smith on Using machine learning to accommodate complexity in phylogenetics and population genetics. 📅 Join us for this online seminar on Friday @ 11am EST through https://t.co/SZhQIU7Qqb Non-ISCB members can register here: https://t.co/btDV2jykQL
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We generate a phylogeny of Parulidae using UCE data that includes almost all species and we describe ways to deal with data from low quality samples. With co-authors Julie Allen @HannahOish @Peter_Hosner and Rob Guralnick
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Excited to share "A phylogenomic tree of wood-warblers (Aves: Parulidae): Dealing with good, bad, and ugly samples" led by Min Zhao @Jessica_Oswald @RKimball_UF
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In this exciting new preprint, Warwick Vesztrocy et al use Bgee to show that "the most diverged orthologues display the greatest change in gene expression, thus suggesting that they have a greater functional divergence" https://t.co/pHLCgWQJ8j
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