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Dynamic42 GmbH Profile
Dynamic42 GmbH

@Dynamic42_Jena

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We are specialized in the production and development of human, immunocompetent Organ-on-Chip technology for in vitro disease and infection modelling.

Jena / Germany
Joined May 2020
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@Dynamic42_Jena
Dynamic42 GmbH
1 day
MPS vs. OoC.OoC = specific type of MPS.OoC uses microfluidic chips, MPS doesn’t need to.MPS = mini in vitro models of organs/tissues.OoC replicates organ environments with dynamic functions.Key difference: MPS doesn’t always need biomechanical stimulation.
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@Dynamic42_Jena
Dynamic42 GmbH
2 days
🚀 Exciting news! Dynamic42 GmbH is joining the German Accelerator U.S. Market Access Life Sciences program alongside Green Elephant Biotech, CUREosity GmbH, INTU Diagnostics & Sensific GmbH. A pivotal time as FDA & NIH advance non-animal methods like #organonchip tech.
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@Dynamic42_Jena
Dynamic42 GmbH
3 days
Part 7 of our #MPS2025 interview series highlights Adrian Feile, a PhD student at University Hospital Jena. He explores how DPO-dependent quorum sensing affects Vibrio cholerae biofilm behavior in a 3D intestine-on-chip model -->
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@Dynamic42_Jena
Dynamic42 GmbH
8 days
Part 6 of our #MPS2025 series: Meet Daniela Marques, PhD student at @NIMSB_NOVA, Portugal. She develops a microglia crosstalk MPS model of the blood-brain barrier to explore polyphenol metabolites' potential --> @MPS_NOVA.
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@Dynamic42_Jena
Dynamic42 GmbH
9 days
Part 5 of our #MPS2025 series highlights Inês Silva, a PhD student at @NIMSB_NOVA, Portugal. She developed a microphysiological method to study dopaminergic injury and inflammation in Parkinson’s disease. --> .@MPS_NOVA.
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@Dynamic42_Jena
Dynamic42 GmbH
11 days
In part 4 of our #MPS2025 series, Dr. Santamarina (@itqbnova, Portugal) discusses the Horizon EU Twinning Project @MPS_NOVA with Cláudia Santos (NOVA Medical School), focusing on chronic diseases & host-microbe interactions using organ-on-chip tech -->
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@Dynamic42_Jena
Dynamic42 GmbH
15 days
In part 3 of our #MPS2025 series, we interview Kristin Schüler, a PhD student working in Portugal, about her novel scaffold for collagen deposition in cartilage engineering and osteoarthritis modeling. --> #organonchip
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@Dynamic42_Jena
Dynamic42 GmbH
16 days
In part 2 of #MPS2025, we interviewed Dr. Manasa Nandimandalam from Hannover Medical School about her advanced in vitro models simulating intestinal environments for infection and inflammation studies. -->
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@Dynamic42_Jena
Dynamic42 GmbH
17 days
In part 1 of our #MPS2025 interview series, we spoke with Valentin Wegner, a PhD student at University Hospital Jena, about his research on enhancing CAR T-cell efficacy using short-chain fatty acids in an intestinal adenocarcinoma-on-chip model -->
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@Dynamic42_Jena
Dynamic42 GmbH
22 days
🎉 Congratulations to Nanci Santos Ferreira for submitting the closest guess in our competition and winning a LEGO® clean bench. We are sure it will make a nice addition to your collection.
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@Dynamic42_Jena
Dynamic42 GmbH
22 days
“I am always excited to have something new in the lab”. Anne talks about how she uses our liver-on-chip model for #toxicity screening. Meet Anni today at #MPS2025 at her poster "Microphysiological #organonchip models for therapeutic antibody validation and safety testing"
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@Dynamic42_Jena
Dynamic42 GmbH
23 days
Missed #MPS2025? Here's a quick venue tour! 🎥. Visit us at booth #202 for:.PDMS-free biochips 🧪.High sample recovery 🔬.Infection models 🦠.No-capital tech 💡.Advanced cancer models 🎯
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@Dynamic42_Jena
Dynamic42 GmbH
26 days
We are here! The team has arrived safe and sound in Brussels ready to hit #MPS2025 . First up is Amélie in the 3-min-thesis competition. She is going to talk about "A cancer-on-chip model to monitor the impact of the TME on immune cells". From Tuesday meet us at booth #202 .
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@Dynamic42_Jena
Dynamic42 GmbH
29 days
Let's be honest, all of us in the field of #organonchip have encountered it. We talk about what we do & people literally think that we place a complete human organ on a chip. 🤣 . anyway we are looking forward to talking all things #ooc & #mps at #MPS2025 in Brussels next week.
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@Dynamic42_Jena
Dynamic42 GmbH
1 month
In the quest for her master thesis Noreen stumbled over #organonchip models for infection research on Aspergillus fumigatus. The topic immediately intrigued her and she is working on it to date.
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@Dynamic42_Jena
Dynamic42 GmbH
1 month
As #NationalCancerResearchMonth wraps up, our team is reflecting on their #AACR highlights (besides visiting Chicago 😄): Advances in ADCs, T-cell engagers, AI-driven oncology & tumor microenvironment research and spheroid-on-chip culture as valuable tool for cancer research.
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@Dynamic42_Jena
Dynamic42 GmbH
1 month
🚨 Last chance to register! 🚨. Don't miss our webinar on the multi-organ-on-chip model for drug safety in pregnancy—TOMORROW at 4 pm CEST (10 am EST)!. Join experts Christian Maass & Katja Graf. Register now:
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@Dynamic42_Jena
Dynamic42 GmbH
2 months
Join our webinar with InfectoGnostics Jena! Learn how #organonchip models could replace, reduce & refine animal testing in drug & biomedical research. Discover current capabilities & challenges. Register here:
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@Dynamic42_Jena
Dynamic42 GmbH
2 months
Where are TEER measurement useful?.1. Prediction of drug-induced disruption of cell-cell contacts or cell death.2. Understanding mechanisms of disease, injuries and drugs .3. Study of infection processes and translocation of pathogens.4. Quality control in tissue engineering.
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@Dynamic42_Jena
Dynamic42 GmbH
2 months
1 Week Left! Join our webinar on May 22, 4 PM CEST to explore organ-on-chip models in drug safety during pregnancy. 🎯 Highlights:.• Intestine-liver-placenta model.• Digital twins in pharmacokinetics.• Prednisone case study.Register now:
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