Iago Pinal-Fernandez
@DrIagoPinal
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Dr. Pinal-Fernandez is a Staff Clinician at the Muscle Disease Unit of NIAMS/NIH. His research is focused on understanding myositis and autoimmunity.
NIAMS/NIH, Bethesda, MD
Joined October 2021
Pathological autoantibody internalisation in myositis. In myositis, autoantibodies are internalized into living cells, disrupting the function of their autoantigen. Annals of the Rheumatic Diseases 2024
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Distinct cytokine and cytokine receptor expression patterns characterize different forms of myositis. Rheumatology 2025.
academic.oup.com
AbstractObjective. Myositis is a heterogeneous family of inflammatory myopathies. We sought to define the differential expression of cytokines, cytokine re
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RT @DrIagoPinal: Characterizing local antibody responses in the muscle of inclusion body myositis patients. Journal of Autoimmunity 2025.….
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Characterizing local antibody responses in the muscle of inclusion body myositis patients. Journal of Autoimmunity 2025.
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RT @DrIagoPinal: Exploring novel therapies for idiopathic inflammatory myopathies and examining future perspectives. Current Treatment Opt….
link.springer.com
Current Treatment Options in Rheumatology - This review aims to summarize the landscape of therapies that are currently being tested or planned in patients with idiopathic inflammatory myopathies...
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RT @DrIagoPinal: Treatment and Monitoring of Eosinophilic Fasciitis. Current Treatment Options in Rheumatology 2025. .
link.springer.com
Current Treatment Options in Rheumatology - Eosinophilic fasciitis (EF) is a rare inflammatory disease characterized by skin induration. Although some guidelines from scientific societies exist,...
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RT @DrIagoPinal: Mitochondrial damage is associated with an early immune response in inclusion body myositis. Brain 2025. .
academic.oup.com
Polymyositis with mitochondrial pathology (PM-Mito) is an early form of Inclusion Body Myositis (IBM). Kleefeld et al. identify mitochondrial abnormalities
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RT @DrIagoPinal: Unicorns, dragons, antisynthetase-negative antisynthetase syndrome, and other mythologic beasts. Annals of the Rheumatic D….
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Exploring novel therapies for idiopathic inflammatory myopathies and examining future perspectives. Current Treatment Options in Rheumatology 2025.
link.springer.com
Current Treatment Options in Rheumatology - This review aims to summarize the landscape of therapies that are currently being tested or planned in patients with idiopathic inflammatory myopathies...
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Treatment and Monitoring of Eosinophilic Fasciitis. Current Treatment Options in Rheumatology 2025.
link.springer.com
Current Treatment Options in Rheumatology - Eosinophilic fasciitis (EF) is a rare inflammatory disease characterized by skin induration. Although some guidelines from scientific societies exist,...
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Mitochondrial damage is associated with an early immune response in inclusion body myositis. Brain 2025.
academic.oup.com
Polymyositis with mitochondrial pathology (PM-Mito) is an early form of Inclusion Body Myositis (IBM). Kleefeld et al. identify mitochondrial abnormalities
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Unicorns, dragons, antisynthetase-negative antisynthetase syndrome, and other mythologic beasts. Annals of the Rheumatic Diseases 2025.
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RT @TLiewluck: Emerging atypical manifestations of immune-mediate necrotizing #myopathy (#myositis): early recognition of these cases is ve….
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Immune Checkpoint Inhibitor Myopathy: The Double-Edged Sword of Cancer Immunotherapy. Neurology 2024.
neurology.org
Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of several malignancies, with improved survival. These monoclonal antibodies target immune checkpoints, including cytotoxic...
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RT @DrAiLynTan: Factors that contribute to #myositis-specific autoantibodies which can infiltrate #muscle cells. ▶️Pre-existing diseases.▶️….
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RT @DrIagoPinal: Recent Updates on the Pathogenesis of Inflammatory Myopathies. Current Rheumatology Reports 2024. .
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Recent Updates on the Pathogenesis of Inflammatory Myopathies. Current Rheumatology Reports 2024.
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Quantification of Autoantibodies Using a Luminescent Profiling Method in Autoimmune Interstitial Lung Diseases. Frontiers in Immunology 2024.
frontiersin.org
Autoantibodies are important for the diagnosis of autoimmune interstitial lung disease (ILD). Standard immunoassays have limitations, including their qualita...
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In Myositis, Autoantibodies Get Inside Muscle Cells and Disrupt the Function of their Target Proteins
niams.nih.gov
OverviewAn international team of researchers, led by the NIAMS Intramural Research Progr
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RT @grieshaber: It was great to receive an inspiring lecture on the role of mitochondrial dysfunction in myositis by @DrOlivierBoyer from @….
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RT @DrIagoPinal: Pathological autoantibody internalisation in myositis. In myositis, autoantibodies are internalize….
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