Dr Graham Lloyd-Jones
@DrGrahamLJ
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Consultant Radiologist. Anatomist. Founder of @RadMasterclass. Linking poor #OralHealth to #ChronicDisease of the body. No reply to anon accounts. Views mine.
Salisbury, Wiltshire, UK
Joined November 2021
In summary… Acute COVID with neurological symptoms commonly manifests as vascular phenomena in the brain visible with MRI … (My) bigger picture summary… COVID-19 IS A VASCULAR DISEASE NOT A PNEUMONIA! (and that includes the lung disease) Thanks for reading
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… perhaps meaning the vascular phenomena were underestimated - even though vascular phenomena were already found to be dominant.
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Possible limitations… The study aimed to build a framework for describing the patterns of COVID as seen on brain MRI. But the patterns were ‘predefined’ meaning that some phenomena (including certain vascular phenomena) were not included in the proposed criteria …
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(Which makes sense to me as this is what occurs/occurred in the lungs in those with acute COVID caused by early variants)
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The authors speculate that thrombotic microangiopathy (diseased small blood vessels due to clotting) may explain the pathology of the vascular MRI findings…
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But! What looks like microhaemorrhage (microscopic bleeds) on brain MRI may correspond to microthrombi (microscopic clots) (As is acknowledged) …
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Haemorrhagic (bleeding) phenomena were also common (and associated with high mortality) …
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Large vessel strokes more common than small vessel The large white area is abnormal
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458 brains studied First wave of pandemic (so not applicable to later/current variants) Most common finding = ischaemic infarct (stroke) See image B-F
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Recently published large study of brain MRI in acute #COVID shows vascular phenomena are common. Here are some highlights…. A thread. Link to study 👇👇👇 https://t.co/fL8pv2IUiN
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No they are not ‘treats’ they are poison* *some poisons kill you slowly
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A little reminder that we (scientists and other humans) should NEVER talk about the #GutMicrobiome without also talking about the #OralMicrobiome. The mouth is upstream, you see? 👇👇👇 https://t.co/1DxK4dGho2
#GumDiseaseBacteriaGetEverywhere
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A note for reviewer 2 … All radiology is retrospective! A bit like all photography is retrospective. (Once the picture has been taken, it is in the past, you see?) Thanks!
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This!
Government are proposing a ban on sales of energy drinks to kids. We called for this. We applaud this. Ministers say they want to shift the focus from treatment to prevention. Sign here and tell them to go further and faster on reining in #BigFood. 👇 https://t.co/IcqWMAD6rd
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A new poll of 4000 children found half saw unhealthy food and drink products from either businesses or influencers on social media in the last month. 4 in 10 said they engaged with these posts. Government needs to go further and faster on sugar https://t.co/IcqWMAD6rd
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Anatomical/embryological thought for the day ... The appendix is an outpouching of the tube of the gut. So are the lung airways! And upstream of the whole gut tube is ... The mouth! (Other gut outpouchings downstream of the mouth are available) #NotJustACakeHole
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We need a new word for being content and frustrated in equal measure. What's your vote?
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The vagus nerve doesn’t supply the gastrointestinal tract, just a bit of it. And there are two of them, not one. And they are left handed (left anterior to right) And the mouth is still more important than this gut-brain axis nonsense. #oralgutbrainaxis
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Thought for the day ... You don't eat with your gut, you eat with your mouth. The gut is downstream from your mouth. The health of your gut (and gut microbiome) depends on the health of your mouth (and oral microbiome). Stop studying the gut as if the mouth doesn't exist.
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