@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@RiganoESQ @elonmusk @DiderRaoult 42 patients Non randomized Non blinded Not analyzed via intention to treat Surrogate primary endpoint 6 days follow up Interesting? Sure. But this is the kind of thing that should prompt a legit clinical trial, not advocacy for broad use of an unproven drug in 1000s of people.
31
26
292

Replies

@elonmusk
Elon Musk
4 years
Maybe worth considering chloroquine for C19
3K
11K
48K
@elonmusk
Elon Musk
4 years
Hydroxychloroquine probably better
Tweet media one
1K
4K
15K
@RiganoESQ
Gregory Rigano
4 years
@elonmusk I am co-author of the original paper. Was just on television discussing HCQ, first well controlled study against COVID-19. 600 mg HCQ per day after 6 days, 90% of patients tested COVID-19 negative. 96% of control group tested positive after 6 days. DM or grigano1 @jhu .edu
227
2K
5K
@RiganoESQ
Gregory Rigano
4 years
@elonmusk Update: As per @DiderRaoult - the study shows combination of HCQ * Azithromycin is most effective treatment 1 control group (placebo) 1 HCQ group 1 HCQ * Azithromycin group follow his youtube for more info, major announcements coming ...
89
717
2K
@elonmusk
Elon Musk
4 years
@RiganoESQ @DiderRaoult Whether Z-pak works in this situation or not, it’s a kickass med for many maladies
109
176
2K
@RiganoESQ
Gregory Rigano
4 years
@elonmusk @DiderRaoult UPDATE: Full peer reviewed study has been released by Didier Raoult MD, PhD . After 6 days 100% of patients treated with HCQ + Azithromycin were virologically cured p-value <.0001
911
7K
13K
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@RiganoESQ @elonmusk @DiderRaoult To everyone saying, "what's the harm?" & "it's been around for 50 years and totally safe!", here's a good summary of why we should be cautious re: chloroquine, including the fact that for at least one virus, chikungunya, it appears to worsen the disease. (
4
3
7
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@Jsw912 @RiganoESQ @elonmusk @DiderRaoult It is not "proven". πŸ™„ I agree there should be a trial - as in a well designed, blinded, randomized clinical trial with a patient-centered endpoint (e.g death, need for intubation, ICU days, etc...) That is not remotely the same thing as just giving the drug to everyone.
8
0
26
@luciarosa90
Lucia
4 years
@DrEricStrong @RiganoESQ @elonmusk @DiderRaoult Completely agree! 6 pts β€œlost to follow up” and no ITT. In fact 3 pts went to ITU and 1 died! In saying that, chloroquine and hydrozychloroquine are cheap, widely available and pretty safe PO drugs. Worth a shot where little else available.
1
0
0
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@DavidRimshnick @RiganoESQ @elonmusk @DiderRaoult Lol...meaning the investigators were not blinded, not referring to the patients.
0
0
0
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@huffsjenkem @RiganoESQ @elonmusk @DiderRaoult So saying that a finding is interesting and warrants further study is ruthlessly extinguishing every single ray of hope? πŸ€”
1
0
0
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@TinaVaine @RiganoESQ @elonmusk @DiderRaoult Ethics?!? Are you familiar with the ancient concept of primum non nocere, or "first, do no harm"? There is nothing ethical in giving a potentially dangerous drug of unknown benefit to people & depleting supplies for those who actually need it for established indications.
0
0
5
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
0
0
0
@brenmarkebrche1
bΓ€renmarkebΓ€rchen
4 years
@DrEricStrong @RiganoESQ @elonmusk @DiderRaoult Thank you! Everybody with knowledge about clinical trials can easily identify the weaknesses of this paper. Do people really want a treatment that was only tested on 20 participants?
0
0
1
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@Tc5812 @RiganoESQ @elonmusk @DiderRaoult Since when did medical science become a political litmus test?
0
0
3
@DrEricStrong
Eric Strong πŸ‡ΊπŸ‡¦πŸ‰ 🩺 πŸ₯ΎπŸ‹οΈ
4 years
@Louise49153139 @RiganoESQ @elonmusk @DiderRaoult "Right to try" is a dangerous slippery slope that undermines medical progress and abuses patients who are at their most vulnerable moments.
0
0
0
@FactorOne
Fossil Chops Jort Borts Derk #SlavaUkraini πŸ‡ΊπŸ‡¦
4 years
@DrEricStrong @RiganoESQ @elonmusk @DiderRaoult I also find it dubious that they're trying them in conjunction with Azithromycin, which is an antibiotic and would only be useful if patients have pneumonia or are at risk of developing it already. If that's the case, then it's entirely possible that the Z-pak is what's working.
0
0
1
@BartFinkk
kaoma . .
4 years
@DrEricStrong @RiganoESQ @elonmusk @DiderRaoult The treatment was successfully tested in France by Dr. Raoult, and larger scale clinical tests are ongoing with Hydroxychloroquine and Azithromycin
0
0
0