Donald Weaver
@DrDonWeaver
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Senior Scientist, Krembil Brain Institute at @UHN. Professor, University of Toronto (@UofT)
Toronto, Ontario, Canada
Joined October 2014
SHIELD: A simple, memorable model to help prevent Alzheimer’s disease and dementia https://t.co/cqm7e8WHFa via @ConversationCA
theconversation.com
The SHIELD (Sleep, Head Injury prevention, Exercise, Learning, and Diet) mnemonic offers a clear and effective strategy for lowering dementia risk.
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It’s unlikely a magic bullet will ever cure Alzheimer’s – maybe a magic shotgun can https://t.co/318wH0NFWb via @ConversationUK
theconversation.com
Alzheimer’s researcher Donald Weaver tells The Conversation Weekly podcast what he’s learnt during more than 30 years of studying the disease.
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Should AD stand for Alzheimer’s disease, or for Auguste Deter, the patient whose case was first described? https://t.co/9RS2ZyJBna via @ConversationCA
theconversation.com
Dementia patient Auguste Deter’s contribution to the 1907 single case report study by Alois Alzheimer was immense: Deter’s life, illness and death are the story of Alzeimer’s disease.
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Curing Alzheimer’s disease: Magic bullet or magic shotgun blast? https://t.co/S0v5QyealT via @ConversationCA
theconversation.com
Rather than seeking a single cure — a magic bullet — for Alzheimer’s disease, a shotgun blast of different drugs with different targets may be a better approach to this very complex condition.
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January is Alzheimer's Awareness Month. Learn how @DrDonWeaver and researchers at @KBI_UHN are making strides to better understand the disease and develop new approaches to treatment.
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Pleased to present at the Clinical Trials Ontario conference. Expanding access to clinical trials in community hospitals & remote sites is crucial to ensuring all Ontarians have the opportunity to benefit from the latest treatments. #ClinicalTrials #HealthEquity #CTOconf2024
Carley McPherson, Dir. of Research @LakeridgeHealth, shares how community hospitals are critical to Ontario’s clinical trials network, enhancing accessibility and care delivery. #CommunityHealthcare #ClinicalTrials #CTOConf2024 @LakeridgeHealth @cmcpher
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Pleased to announce a new publication in Nature Communications: "Computer aided drug design to generate a unique antibiotic family" https://t.co/WIJOtibc87 Computer-aided molecular design technologies are crucial tools in modern approaches to drug design and discovery.
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World Alzheimer's Day We must embrace research and strive, We must caress the living lives Of loving ones with tales untold As glia dance, proteins misfold. Diseases of our brain and mind, Cruel enemy of humankind. To cure AD – the mind, the brain, With scientific hand humane.
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Chloe Baloh and Emma Twiss from the Weaver Lab placed 1st and 2nd today at the Krembil Research Institute Summer Student Research Day for their work on Alzheimer's Disease. Congratulations!!
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🩸💉Major strides in early Alzheimer’s detection! Study shows a new blood test may be able to detect Alzheimer’s early–with 90% accuracy. “Early diagnosis is important,” said @DrDonWeaver to @CTVNews regarding the findings. Watch the interview now: https://t.co/2qVpgphJOf
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Here is the Treventis #AAIC24 contingent! Drop us a line if you're in Philadelphia this week and would like to meet.
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Endogenous Antimicrobial-Immunomodulatory Molecules: Networking Biomolecules of Innate Immunity (D. F. Weaver) @DrDonWeaver #openaccess
chemistry-europe.onlinelibrary.wiley.com
A network of biomolecules (peptides, saccharides, lipids, nucleic acids, organic molecules, metal ions) endogenous to the human brain and exhibiting both antimicrobial and immunomodulatory activiti...
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β-Amyloid is a cytokine (kinocidin-type); where kinocidins are immunopeptides with the properties of both cytokines and antimicrobial peptides. What are the implications for drug design for AD? β-Amyloid Is a Kinocidin Cytokine | ACS Chemical Neuroscience
pubs.acs.org
Although β-amyloid (Aβ) has long been studied as a key contributor to the pathology of Alzheimer’s disease (AD), its physiological role (if any) remains undetermined. This Viewpoint highlights the...
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See: https://t.co/9VxfHUmWKh An important commentary on the ballooning economic cost of dementia and the need for better resourced research on neurodegeneration. We can pay now or we can pay more later!
scientificamerican.com
A new model of Alzheimer’s predicts a staggering economic burden and justifies substantial investments in research, testing, treatments and public-health outreach
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Research is our only path to a better tomorrow. Words we must remember, especially within the context of humankind's struggle to conquer neurodegenerative disease.
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Endogenous Antimicrobial-Immunomodulatory Molecules: Networking Biomolecules of Innate Immunity https://t.co/7KwYyCXcoy Beta-Amyloid is part of a synergistic self-triggering network of antimicrobial-immunomodulatory molecules - perhaps a useful insight for drug design!
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Chemists Invent Drugs and Drugs Save Lives - Weaver - ChemMedChem - Wiley Online Library
chemistry-europe.onlinelibrary.wiley.com
The fact that drug molecules are designed, created and invented by chemists remains largely unknown by the general public – an omission which is merely one aspect of a widespread general underappre...
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Medicinal chemistry/drug design is indeed a crucial element in the health and socioeconomic well-being of humankind.
A very interesting @ChemMedChem editorial by @DrDonWeaver reminds of the underappreciation of the role of medicinal chemistry in the health and socioeconomic well-being of humankind, even if drugs are designed, created and invented by medicinal chemists. https://t.co/KZUeMO9fIr
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So many illnesses affecting humankind; we need to be passionate about drug design and drug discovery
If you read one thing today, make it this devastatingly moving editorial from Donald Weaver. I’ve heard many stories of how folks became true believers in the drug discovery cause & the power of medicinal chemistry, but this one tops them all. Big feels. https://t.co/NtbUZguMS4
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