The Sprague Lab at MUSC
@Dan_Sprague_Lab
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Account for the Sprague Group at the Medical University of South Carolina. Follow to see the latest news, pubs, and science. Reach out any time!
Charleston, SC
Joined May 2024
Our new paper is officially out in @ACSPublications ACS Infectious Diseases! This was a fun one! Who knew a thioamide could be so interesting?! . I also want to highlight Connor, our undergrad @CofCChem who contributed - his FIRST paper! Congrats all!.
pubs.acs.org
The drug praziquantel (PZQ) has been used for decades to treat clinical and veterinary infections caused by parasitic flatworms. Although PZQ is efficacious against many different types of flukes and...
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The first paper with work from our lab is out today in @ScienceAdvances!! This was a collaborative effort with the Gan Lab here @MedUnivSC, and we are extremely grateful to have been able to contribute to their continuing efforts to understand PTMs!!.
science.org
BRD9 activates the AKT-EZH2 pathway to facilitate tumorigenesis through its noncanonical role as a methylarginine reader.
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Hepatic stellate cells are really cool. Just saying. That's it. That's the tweet! More to come in the future.
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RT @VanderbiltChem: Alumni Spotlight: Dan Sprague, PhD (Asst. Prof. of Biochemistry & Molecular Biology, Medical University of SC).This Fri….
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Today, we welcome Connor Barth into the lab as an undergraduate researcher from the College of Charleston. Time to make some molecules!!!! We're excited to have someone new excited about synthesis in the lab!😀.
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We've had an eventful end of semester - the lab is growing! We're super excited to welcome Alison Bland as our Research Specialist and to add Julia Staton to the team for Rotation #2. Time to start investigating new signaling pathways -- in worms and in cancer! Welcome all! 😀.
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Fantastic end-of-rotation talk today from @ana_pettijohn! Fielded questions like a champ! We wish her well as she heads to her next rotation!!
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We're SUPER excited to welcome our first student, @ana_pettijohn, to the lab for the first rotation this year! Ana comes with a Total Synthesis background from Coastal Carolina, and we're going to see what trouble she can get into while developing new antiparasitics! Can't wait!.
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And the Chemistry Gods said "Let there be Chemistry!" And a functioning hood appeared!. We're so excited to finally have a functioning fume hood. Chemistry starts next week!!!!!
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Are you a grad student working in molecular, cellular, or immunoparasitology? Do you want a talk and free registration to #TropMed24? Submit to the ACMCIP 3MT -- a great opportunity! Please pass this along to anyone you know who could be interested. Reach out with any questions!
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Dan's work from the @MarchantLab is a featured article!!!! Flukicides for the win! (Thanks to Jonathan for taking one for the team and making the in-person video!).
Parasitic flatworms known, as flukes or trematodes, are responsible for some of the most debilitating neglected tropical diseases (NTDs) affecting billions of people worldwide. Schistosomiasis, caused by blood flukes, is a significant health risk in many tropical regions. The
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RT @ErrantScience: Getting back reviewer comments always feels like life and death, but it's rarely that dramatic. unless you drama-it-up….
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The lab's first Chemglass order is here!!!! Time to unpack and organize!
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@MedUnivSC Thank you to all of my mentors throughout the years, including Norito (twitterless), Jeff (@chiralproton), Brian (@BrianC_Smith), and Jonathan (@MarchantLab).
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Hello World! We're so excited to be opening our doors @MedUnivSC on 6/3/24! Looking forward to connecting with everyone! Stay tuned for some fun science!.
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