David Yang
@DYangMD
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Radiation Oncologist at @DanaFarber @BrighamWomens @harvardmed and Research Fellow in @VanAllenLab. All views are my own.
Boston, MA
Joined December 2009
RT @JoshLangMD: Tonight we sit with the cherished memories of a truly unforgettable individual who changed the lives of so many fighting ca….
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@KatieLeeMDPhD @MtkingMD If further validated, AI-determined tumor volume may become a novel biomarker for improving risk stratification for pts w/ localized PCa (in addition to genomics and computational pathology approaches) 7/n.
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@KatieLeeMDPhD @MtkingMD The AI-determined tumor volume may also have greater performance for predicting MFS than NCCN risk groups (e.g. AUROC for 7y MFS 0.84 vs 0.74, p=0.02 for RT-treated patients) 6/n.
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@KatieLeeMDPhD @MtkingMD Particularly interesting was our observation the intraprostatic tumor size was associated with both BCR and MFS for both RT and RP-treated patients, even after adjusting for the clinical, radiologic, and pathologic characteristics 5/n.
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@KatieLeeMDPhD @MtkingMD Using a cohort of 732 patients w/ PCa and mpMRIs, we built a segmentation model with the nnU-Net approach which showed good performance (e.g. F1 scores of 84-87% for PI-RADS 3-5 lesions across training/test cohorts) 4/n.
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@KatieLeeMDPhD @MtkingMD We envisioned that this model would be useful in several ways, such as for focal microboosts for EBRT: 3/n.
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@KatieLeeMDPhD @MtkingMD We initially became interested in building a deep learning model for segmenting the intraprostatic tumor from prostate mpMRIs (though noting that we were certainly not the first to attempt this task, e.g. 2/n.
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Excited to share work with coauthors Leslie Lee, @KatieLeeMDPhD @MtkingMD and others on "AI-derived Tumor Volume from Multiparametric MRI and Outcomes in Localized Prostate Cancer." A tweetorial: 1/n.
The volume of AI-segmented prostatic tumors was an independent prognostic factor for outcomes of localized prostate cancer treated with radical prostatectomy and radiation therapy. @BrighamRadOnc @DYangMD @KatieLeeMDPHD @MtkingMD
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RT @VanAllenLab: Hi folks - our lab in @DFCIPopSci has an opening for a post-doctoral fellow at the interface of prostate cancer and AI via….
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Incredibly grateful for @PCF_Science for graciously supporting our work and @DrPaulNguyen @VanAllenLab and @MtkingMD for their wonderful mentorship!.
🏆 Congratulations to @DYangMD on receiving the prestigious @PCFnews Young Investigator Award to work on Uncovering novel biomarkers in localized prostate cancer through radiomics and digital pathology! Mentors @VanAllenLab @DrPaulNguyen @MtkingMD .
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Many thanks to @DKirschMDPhD for joining @HarvardRadOnc as Visiting Professor. The residency #classof2005 was clearly something special! @HenningWillers #helenshih.
Such a treat to hear @DKirschMDPhD speak on his now a couple of decades spanning research in the famous @MassGeneralNews Ether Dome🙏. Good to know p53 is alive + well😊. Absolute photo op pleasure with Helen Shih & then residency program director Anthony Zietman #ClassOf2005 👍
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We are delighted to have @DrWinkfield join @HarvardRadOnc as our Visiting Professor! Thank you for sharing all the inspirational and impactful work you’ve done on health equity!
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RT @TracyABalboni: What an inspirational talk by our HROP Visiting Prof Dr. Karen Winkfield!! Thank you for inspiring us with your passion,….
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RT @HarvardRadOnc: Today we were delighted and grateful to have Dr. Paul Brown from @MayoRadOnc join us as a Visiting Professor! #RadOnc #M….
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RT @HarvardRadOnc: 1 week until our first virtual meet & greet! Spots are still available. Get your questions answered about residency from….
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RT @HarvardRadOnc: This is going to great event hosted by @ASarafMD2 @kevinxliu @AmyWisdom8 @BrandonTurnerMD @DYangMD. What questions do yo….
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RT @ShannonMacDonMD: My #first tweet- to bring attention to the outdated 18th century laws prohibiting us from providing healthcare to pati….
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