DO-IT Trial
@DOIT_trial
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📊 Global, multicenter RCT ischemic#stroke 🔬 Investigating thrombolysis to improve mRS in people with recent DOAC intake 🌐 ClinicalTrials NCT06571149 @snf_ch
@StrokeBern @PHRIresearch
Joined November 2023
🚨 University Hospital Basel is now an active site for the @DOIT_trial ! 🧠. We're one step closer to advancing stroke care for people suffering ischemic stroke despite #DOAC treatment. Learn more 👉 #DOIT @StrokeBern.
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🚀BREAKING news! The second trial site for the DO-IT Trial has officially opened in St.Gallen! 🎉😁 We would like to welcome the trial team in St. Gallen to the DO-IT.community, we are thrilled to have you on board. Stay tuned for the upcoming site opening in Basel…⏲️
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🚨 Exciting news! 🚨.The first patient has been randomised into the DO-IT Trial! 🎉. A big congratulations to the trial team in Bern on this amazing achievement!. This marks a major milestone! A huge thank you to everyone for making this possible!. Stay tuned for more updates.
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🚀BREAKING news! The first trial site for the DO-IT Trial has officially opened in Bern! 🎉🙌 A big thank you to everyone involved for their support and hard work. Stay tuned for more updates on site openings across Swtizerland! 🌍 #DOITTrial.
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RT @DavidSeiffge: Nearly half of all AF-related strokes are #breakthroughstrokes despite adequate anticoagulation therapy. Low rate of thro….
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RT @McmasterStroke: The @DOIT_trial team celebrating at #WSC2024 on the heels of @DavidSeiffge’s successful debate and @TotoMynell’s succes….
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RT @DavidSeiffge: Preparing for my talk about #breakthroughstrokes at the Norwegian Stroke Meeting in Bergen tomorrow with my friend @EspnS….
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Definitely equipoise to randomize in the starting #RCT @DOIT_trial .Reach out if interested.@DavidSeiffge @TotoMynell @lucianacatanese @FishingNeurons .
Don’t miss out on the debate between me and my friend and colleague @DavidSeiffge on IV thrombolysis in patients with recent DOAC use at WSC next week. It’s clear who will win the debate 😉 @WorldStrokeEd @WorldStrokeOrg #stroke @StrokeAHA_ASA
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RT @TotoMynell: The main question this excellent study raises is whether we should give IVT to patients on DOACs. Despite very high dose of….
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RT @TotoMynell: • 81 yo female.• Aphasia, slight HP R, NIHSS 10.• LSW 2h ago.• on Rivaroxaban, plasma level 334ng/ml .• no LVO https://t.co….
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RT @DavidSeiffge: Thanks for highlighting the importance ti get additional data on IVT in patients on DOACS. We will just @DOIT_trial !@jan….
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RT @DavidSeiffge: @EspnSaxKristoff @SPAVC_pt @Diana_A_Sousa @DOIT_trial @TotoMynell Great international effort to determine safety and effi….
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RT @Mo_majali91: Excited to share our work on the safety of thrombolytics in patients on DOACs. Largest sample size in the literature. Grea….
ahajournals.org
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DM us for participating in the prospective DO-IT registry and RCT.
Great work by @GhannamMalik and co-authors. Thrombolysis in patients w suspected ischemic stroke & recent DOAC ingestion seems safe in this meta-analysis. Given the retrospective nature of studies & no core lab adjudication, findings need validation.
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