DO-IT Trial
@DOIT_trial
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📊 Global, multicenter RCT ischemic#stroke 🔬 Investigating thrombolysis to improve mRS in people with recent DOAC intake 🌐 ClinicalTrials NCT06571149 @snf_ch
@StrokeBern @PHRIresearch
Joined November 2023
🚨 Missed it? Catch up on the Stroke Alert Podcast featuring @TotoMynell on the DO-IT Target Trial Analysis — key insights into thrombolysis in DOAC-treated stroke patients. Don’t miss this one! 🎧 Stroke Alert October 2025
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The DO-IT study is gaining momentum in Europe, and Canada is next! 🇨🇦 Are you ready to DO IT? 👍💪💉
🔊 Exciting DO-IT Trial Update!🔊 📈 🌍 The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far! - 27 in🇨🇭 - 3 in the 🇳🇱 - 2 in 🇧🇪 - 1 in 🇪🇸 👏 A big thank you to everyone contributing! 💉🧑⚕️Recruit. Care. Cure. DO-IT!
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🔊 Exciting DO-IT Trial Update! 🔊 🌍 📈 Just this week, we received final regulatory approval for additional sites in Germany, Spain, the Netherlands and Belgium through CTIS. Thus, a total of 52 sites have already been approved! 🇩🇪🇪🇸🇳🇱🇧🇪 💉🧑⚕️Small Steps. Big Impact. DO-IT!
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🔊 Exciting DO-IT Trial Update!🔊 📈 🌍 The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far! - 27 in🇨🇭 - 3 in the 🇳🇱 - 2 in 🇧🇪 - 1 in 🇪🇸 👏 A big thank you to everyone contributing! 💉🧑⚕️Recruit. Care. Cure. DO-IT!
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🚨Exciting DO-IT Trial Update!🚨 Co-funding has been granted from PHRC-N for France. A big thank you to Guillaume Turc and their teams for this great accomplishment.
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🔊 Exciting DO-IT Trial Update!🔊 📈 🌍 The trial continues to expand, with 23 sites actively recruiting across Europe and 30 patients enrolled so far! 👏 A big thank you to everyone contributing! 💉🧑⚕️Recruit. Care. Cure. DO-IT!
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🚨Exciting news! 🚨 The first patient in the EU has been randomised into the @DOIT_trial ! 🎉🥳 A big congratulations to Jonathan Coutinho and team in Amsterdam on this amazing achievement! A huge thank you to everyone for making this possible! Stay tuned for more updates.
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📢We would like to welcome the trial teams in Brussels and Sanderbusch to the @DOIT_trial and community. 🥳We very much look forward to have your centers active and recruiting in the coming days. We are thrilled to have you on board.🎉
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✨September was a busy and successful month for the @DOIT_trial ✨Another 3 centers are now active and recruiting.🎉 Thank you to the trial teams in Valladolid, Leuven, and Schleswig! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.
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✨September was a busy and successful month for the @DOIT_trial✨ Another 4 centers are now active and recruiting.🥳 Thank you to the trial teams in Madrid, Amsterdam, Charleroi, and Hamburg! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.
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Co-funding has been granted from the @TheBHF for the UK, DHF for the Netherlands, and Akershus University Hospital, internal open research funding for Norway. Thanks David Werring, Jonathan Coutinho, and Espen Kristoffersen and their teams for this great accomplishment.
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📢Exciting news📢 28 trial sites in Germany, Spain, the Netherlands, and Belgium have received regulatory approval through CTIS! The first trial sites in Germany+Belgium are now recruiting. Many additional trial sites have been submitted for approval!
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🚨 University Hospital Basel is now an active site for the @DOIT_trial ! 🧠 We're one step closer to advancing stroke care for people suffering ischemic stroke despite #DOAC treatment. Learn more 👉 https://t.co/7rnEYEXbIv
#DOIT @StrokeBern
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🚀BREAKING news! The second trial site for the DO-IT Trial has officially opened in St.Gallen! 🎉😁 We would like to welcome the trial team in St. Gallen to the DO-IT community, we are thrilled to have you on board. Stay tuned for the upcoming site opening in Basel…⏲️
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🚨 Exciting news! 🚨 The first patient has been randomised into the DO-IT Trial! 🎉 A big congratulations to the trial team in Bern on this amazing achievement! This marks a major milestone! A huge thank you to everyone for making this possible! Stay tuned for more updates.
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🚀BREAKING news! The first trial site for the DO-IT Trial has officially opened in Bern! 🎉🙌 A big thank you to everyone involved for their support and hard work. Stay tuned for more updates on site openings across Swtizerland! 🌍 #DOITTrial
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Nearly half of all AF-related strokes are #breakthroughstrokes despite adequate anticoagulation therapy. Low rate of thrombolysis. Better secondary prevention treatments and efficacy data for IVT in DOAC patients needed to change guidelines @ELAPSETrial @DOIT_trial @StrokeBern
Just Accepted! 🗞️Anticoagulation Usage and Thrombolytic Therapy in Subjects with Atrial Fibrillation Associated Ischaemic #Stroke
https://t.co/zIRXH4IGpS
@CamStroke
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Just Accepted! 🗞️Anticoagulation Usage and Thrombolytic Therapy in Subjects with Atrial Fibrillation Associated Ischaemic #Stroke
https://t.co/zIRXH4IGpS
@CamStroke
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The @DOIT_trial team celebrating at #WSC2024 on the heels of @DavidSeiffge’s successful debate and @TotoMynell’s successful Swiss National Sciences Foundation funding application! We’re looking forward to launching the trial imminently!! @StrokeBern @PHRIresearch #stroke #MedEd
@martagares97 @WorldStrokeOrg @WorldStrokeEd @ShadiYaghi2 Thanks @ShadiYaghi2 , this was a great debate! Good to know that we essentially agree! @StrokeBern and @PHRIresearch will do our best to @DOIT_trial ! @TotoMynell @lucianacatanese @FishingNeurons @Ash_Shoamanesh @ArKatsanos @ESOstroke @WorldStrokeOrg
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