Cracking Cancer Podcast
@Cracking_Cancer
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Cracking Cancer is a podcast by patients and providers that breaks down barriers through mutual education. All profits go to cancer research!
Joined January 2025
Why does drug development cost $2.3 BILLION? 🤔 The number has to account for the 90% failure rate of products that go into human testing (IND). You can't have successes without funding those expensive failures. It's a tough truth. 🤷♀️ 🔗 https://t.co/ugJNlvei9z
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Private pharma companies get their funds from Venture Capitalists—not typically angel investors. 💼 Angel investors are sometimes linked to patient advocacy groups for rare diseases. VCs are taking the big risks on private healthcare development. 🔗 https://t.co/ugJNlvei9z
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Every breakthrough in #lungcancer starts with people who refuse to quit. As Dr @kyleconcannonMD points out, progress comes from relentless dedication. We all need to push treatments forward, give hope, and not stop until cancer does. #StoriesOfLungCancer #LCAM25
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A "small" Phase 1 oncology trial costs $10–20 million. Yes, really. 🤯 They need to be large enough to find an efficacy signal, not just safety. Funding comes from investors or selling stock (if the company is public). Big money for smart medicine. 🔗 https://t.co/ugJNlvei9z
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BIG MYTH BUSTED: Doctors DO NOT get paid or receive kickbacks for enrolling patients in trials. 🚫 The check goes to the institution, not the doctor. The real bias often comes from publication or authorship credit. Check those public salaries! 😉 🔗 https://t.co/ugJNlvei9z
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Phase 1 Trial to FDA Approval: How long? 🕰️ Believe it or not, four years is considered "lightning speed" in pharma! The average is still 8–10 years. Administrative steps alone can take a year. Long timelines, even when trying to speed things up. 🔗 https://t.co/ugJNlvei9z
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Phase 1 = First time a new drug moves from animal testing into patients. 🔬 Now, thanks to smart medicine, we have "seamless clinical trials" (Phase 1/2) that just keep rolling if responses are good. Learning and adapting in real-time! 🔗 https://t.co/ugJNlvei9z
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Phase 1 trials are getting smarter thanks to precision medicine! 🧠 Matching the patient to the drug target, trials move faster, put fewer people at risk, and let doctors know quickly if a drug isn't working. Leading to better patient outcomes. 🔗 https://t.co/ugJNlvei9z
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Pharma companies often get novel disease targets from academic research. Then comes the "bake-off": developing and screening compounds to see if they can effectively hit that target. The drug has to be cost-effective before the big clinical push. 🎯 🔗 https://t.co/ugJNlvei9z
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Taking a new drug from research candidate to patient is a long journey! 🤯 It involves IND studies, FDA applications, manufacturing development, clinical trials, and market release. Getting a seat to see the whole process is a unique responsibility. 🔗 https://t.co/ugJNlvei9z
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Big misconception: Not everyone in the pharmaceutical industry is driven only by money. We met incredible people who truly care about their mission. It's a fantastic reminder that genuine passion exists, even in "ivory towers." 💡 🔗 https://t.co/ugJNlvei9z
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Dr. Ross Camidge, Director of Thoracic Oncology at the Colorado Cancer Center, has guided lung cancer patients for decades. Now facing his own stage IV diagnosis, he joins ALKtALK this Sunday — sharing life from both sides of the stethoscope. 📅 Nov 9 @ 7 pm ET
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Progress in #lungcancer isn’t just months or stats, it’s lives fully lived. As Dr @DRCamidge reminds us, the future is one where cancer is just a part of who we are, not the defining chapter. This #LCAM25, help amplify patient voices & push research forward. #StoriesOfLungCancer
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Pharma is a black box to most people…Including us. In this week’s episode @samantham75074 and @kyleconcannonMD talk with Chief Regulatory Officer Kerry Wentworth of @nuvationbioinc about the behind-the-scenes of pharma. A must listen!
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Podcast Episode · The Cracking Cancer Podcast · 11/06/2025 · 1h 5m
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Check out @SamanthaM75074 on @IASLC Lung Cancer Considered discussing her perspective on “Young Lung Cancer” as a woman diagnosed with stage IV HER2 driven lung cancer in her 30s. Wonder why we do what we do? This is why!
Coming out of wedding week to tell you you MUST listen to this episode of Lung Cancer Considered about the realities of Young Lung Cancer. @YoungLungCancer @OncogeneCancer @Florez_Lab @DFEGFRcenter @DanaFarberNews @EGFRResisters
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Together we are creating positive change! TY @kyleconcannonMD for your support , and hard work to change the perception of lung cancer
Happy lung cancer awareness month from the university of Colorado. Thank you to @TheWRP4LC for putting lung cancer front and center on our green!
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Fatigue in #lungcancer isn’t just “being tired.” It can feel like your body has turned to stone. It’s invisible to others & overwhelming to live through. By talking about it, we push for better support, care & understanding. #StoriesOfLungCancer #LCAM25
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Fact: Testicular cancer is most common in men aged 15 to 35 (average age of diagnosis is 27). This young demographic makes it the leading cause of cancer death by life years lost among adult cancers. A sobering reason for awareness. 😔 🔗 https://t.co/ytrbAfHPl5
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Chemo side effects: The worst one wasn't vomiting, but intense, relentless nausea. 😖 It worsened with each cycle, lasting nearly a full month by the third round. It's a brutal, pervasive symptom that often stands out in memory. 🔗 https://t.co/ytrbAfHPl5
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Happy lung cancer awareness month from the university of Colorado. Thank you to @TheWRP4LC for putting lung cancer front and center on our green!
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