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Costin Antonescu Profile
Costin Antonescu

@CostinAntonescu

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Cell biologist and prof @TorontoMet, dad, and wannabe runner/cyclist. All views and opinions are my own. He/him/his.

Toronto, Canada
Joined August 2009
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@CostinAntonescu
Costin Antonescu
9 months
RT @BanffSNCC: We're excited to announce that conference registration will be opening soon! Visit our website for more details and stay tun….
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@CostinAntonescu
Costin Antonescu
10 months
Students from @TorontoMetSci are running in the Canadian Cancer Society CIBC Run for the Cure this weekend. If you are able to, consider donating to support their efforts!.
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support.cancer.ca
Join me and help change the future of breast cancer!
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@CostinAntonescu
Costin Antonescu
1 year
Don't miss out on an opportunity to give a talk at a great meeting at the Ontario Cell Biology Symposium on Aug12-13. The deadline to submit an abstract to be considered for a talk is Monday August 8th. Lots of talk slots available to students, postdocs, and ECRs!.
@ontcellbio
ontcellbio
1 year
The 2024 Ontario Cell Biology Symposium is fast approaching, just over a month away!. The deadline to submit an abstract to be considered for a talk is *Monday July 8th*. Register and submit your abstract today:
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@CostinAntonescu
Costin Antonescu
1 year
It's time to register and submit your abstract for the 2024 Ontario Cell Biology Symposium (Aug 12-13 in Guelph)!. Priority will be given for students, postdocs, and ECRs to give talks, and lots of opportunities for poster presentations. . Please RT!.
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ontariocellbiology.com
@ontcellbio
ontcellbio
1 year
📢Registration is now open for the 2024 Ontario Cell Biology Symposium!. Join us in Guelph Aug. 12-13 and take part in some great science and discussions. Submit your abstract by July 8th to be considered for a talk.
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@CostinAntonescu
Costin Antonescu
1 year
@SRC_CRS This work is part of a great collaboration with @gingraslab1, Geoff Hesketh, @Botelho_Lab & @SfnImpellizzeri with key contributions from Ose Ibazebo, @as_sumaiya, and @sjamesbautista.
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@CostinAntonescu
Costin Antonescu
1 year
@SRC_CRS We also find evidence that this novel GATOR1/2- GSKβ nutrient sensing pathway controls cell survival under low nutrient conditions, which could reveal new strategies to target certain tumors.
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@CostinAntonescu
Costin Antonescu
1 year
@SRC_CRS What is unique about amino acid control of GSKβ is that this regulation is independent of mTORC1, and hence this signaling pathway controlling GSKβ deviates from the canonical GATOR1/2-RagA/B-mTORC1 signaling pathway.
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@CostinAntonescu
Costin Antonescu
1 year
@SRC_CRS Specifically, we found that the nuclear levels of GSKβ are controlled by amino acid availability and required the amino acid signaling complexes GATOR1 and GATOR2.
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@CostinAntonescu
Costin Antonescu
1 year
@SRC_CRS Previous work showed that targeting of glycogen synthase kinase 3β (GSKβ) to the nucleus under specific conditions gates the ability of GSKβ to control transcription factors like c-myc. We now find that cues derived from cell metabolism regulate the nuclear levels of GSKβ.
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@CostinAntonescu
Costin Antonescu
1 year
I am delighted to share our latest preprint!. In this work led by Diana Schwendener Forkel and supported by @SRC_CRS, we find a new mechanism by which cells adapt to changing nutrient availability to promote cell survival.
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biorxiv.org
The availability of certain amino acids regulates cell survival, proliferation, growth, differentiation, and other cellular functions. Sensing of amino acids that converges on the GATOR1 and GATOR2...
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@CostinAntonescu
Costin Antonescu
1 year
RT @ChemistryTA: I'm looking for a postdoc to join my team! We're starting a new project in point-of-care diagnostics with close collaborat….
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@CostinAntonescu
Costin Antonescu
1 year
Calling all cell biologists 🧪🦠🔬👩‍🔬 in and around Ontario!. The 6th annual Ontario Cell Biology Symposium will be on Aug 12-13 in Guelph, so save the date!. Please RT and share.
@ontcellbio
ontcellbio
1 year
📢📢We are delighted to announce that the 2024 Ontario Cell Biology Symposium will take place on Aug. 12-13 in Guelph!. This is a great opportunity for #cellbiology researchers at all levels to attend and/or present their work. Please RT and save the date, and see you there!
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@CostinAntonescu
Costin Antonescu
2 years
A real pleasure to hear all about #pannexins in cancer in a great seminar by @DrSilviaPenuela during her visit to TMU this week!
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@DrSilviaPenuela
Silvia Penuela
2 years
Glad to be on @VIA_Rail to Toronto instead of driving this morning. Don’t worry @CostinAntonescu I’m almost there
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@CostinAntonescu
Costin Antonescu
2 years
My 12 yo came home from school today and declared the start of the Great Relax. This generation gets it. Happy holidays y’all!
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@CostinAntonescu
Costin Antonescu
2 years
A reflection on today’s prize announcement: we are seldom able to accurately predict the long-term impact of sound science in the short term. Something to keep in mind when reviewing or assessing work by our peers and colleagues.
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@CostinAntonescu
Costin Antonescu
2 years
RT @ImogenRCoePhD: Not today. Not tomorrow. #NoSpaceForHate forever
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@CostinAntonescu
Costin Antonescu
2 years
A fantastic first day at the Ontario Cell Biology Symposium #OCBS2023! Amazing talks, great science, looking forward to day 2.
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@CostinAntonescu
Costin Antonescu
2 years
If you haven't registered for the Ontario Cell Biology Symposium yet, there's still time! . See to register . ➡️ Some limited spots are still available for poster presentation, so submit an abstract and present your work if you haven't already!.
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ontariocellbiology.com
@ontcellbio
ontcellbio
2 years
📢📢Only 2 days left to register for the 2023 Ontario Cell Biology Symposium Aug. 10-11!. Deadline to register and submit and abstract for poster presentation is August 4th, 11:59pm (space permitting), see See you there for some great science 🔬🦠🧪🧫!
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@CostinAntonescu
Costin Antonescu
2 years
Don't miss out on early registration discount and being considered for a talk at the 2023 Ontario Cell Biology Symposium! Deadline July 7th. This will be a great meeting, hope to see you there!.
@ontcellbio
ontcellbio
2 years
📢📢Only 4 days left to submit an abstract to be considered for a talk and to get early registration discounts for the 2023 Ontario cell Biology Symposium (deadline July 7th). Join us in Guelph (or virtually) on Aug. 10-11!. see for more.
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@CostinAntonescu
Costin Antonescu
2 years
RT @DrLisaWillis: Want to work on a super cool human immunology/glycobiology project in a great environment? Come and check out the Willis….
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willisglycobiologylab.com
Glyco-immunology in health and disease
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