NIH Pragmatic Trials Collaboratory
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Supported by @NIH, the NIH Pragmatic Trials Collaboratory is advancing the design, conduct, and dissemination of pragmatic clinical trials.
Joined October 2012
The Duke University School of Nursing will convene healthcare professionals, educators, researchers, community leaders, and policymakers for a 1-day symposium on reducing rural health disparities across North Carolina through collaboration and innovation.
rethinkingclinicaltrials.org
The Duke University School of Nursing will convene healthcare professionals, educators, researchers, community leaders, and policymakers for a 1-day symposium dedicated to reducing rural health...
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📣 In this week's PCT Grand Rounds, @Braindoc_MGH, Kristine Olson, and Daniella Meeker of @YaleMed will present "Use of Ambient AI Scribes to Reduce Administrative Burden and Professional Burnout: Lessons Learned and Future Directions." Join us! #pctGR 🔗 https://t.co/gviAjWp1AA
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We've had a busy year! We made more than 40 contributions to the scientific literature, including the results of 5 of the NIH Collaboratory Trials and much, much more. Take a look at our 2025 publications roundup:
rethinkingclinicaltrials.org
In 2025, NIH Pragmatic Trials Collaboratory investigators published new study designs and trial results, shared insights from program leadership, and developed innovative methods in the design,...
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Our Community Health Improvement Core has published a guide for promoting community health in the context of pragmatic clinical trials embedded in healthcare systems. Learn more ➡️ https://t.co/2uUPTts3PU
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📣 In this week's PCT Grand Rounds, Connor Drake and Susan Spratt of @DukeMedSchool will present "The Eat Well Produce Prescription Trial for Patients with Diabetes at Risk of Food Insecurity." Join us! #pctGR 🔗 https://t.co/US1l5To2rM
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🎙️ The latest episode of our Rethinking Clinical Trials #Podcast features Julie Fritz of @UUtah and Sebastian Tong of @UWMedicine in a discussion about PRaCTICe, a new network research hub of the @NIH CARE for Health Initiative. Learn more ➡️ https://t.co/OGcANrvFig.
rethinkingclinicaltrials.org
In a new episode of the Rethinking Clinical Trials Podcast, Julie Fritz of the University of Utah and Sebastian Tong of the University of Washington expanded on key takeaways from […]
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📣 In this week's PCT Grand Rounds, @LeslieCrofford of @VUMCHealth, Dana Dailey of @UIowa, and @ksluka0101 of @UIowa will present results from FM-TIPs, an NIH Collaboratory Trial. Join us! #pctGR 🔗 https://t.co/ZkfNd1Xj5U
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A targeted community engagement strategy in the FM-TIPS #pragmatictrial was highly effective in increasing recruitment and enrollment, particularly among rural participants who are typically underrepresented in clinical research. ➡️ https://t.co/sZV9J0pobX
#nihHEALinitiative
rethinkingclinicaltrials.org
New findings from FM-TIPS show that targeted community engagement methods are highly effective in increasing recruitment and enrollment, particularly among rural participants who are typically...
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In a recently published substudy from PRIM-ER, three-quarters of critically ill patients who had a goals-of-care conversation in the emergency department saw a change in code status, their care plan, hospice, or updated advance care planning documents. ➡️
rethinkingclinicaltrials.org
In a single-site substudy of the PRIM-ER trial, an intervention to initiate palliative care in the emergency department did not increase the proportion of patients having goals-of-care conversations....
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Materials now available from our NIH-hosted workshop, "Digging Into Dilemmas of #PragmaticTrials." Access slides and videos for all sessions, including a keynote by David Zaas, president of Atrium Health Wake Forest Baptist and professor at @wakeforestmed.
rethinkingclinicaltrials.org
Materials and videocast recordings are now available from the NIH Pragmatic Trials Collaboratory’s recent workshop, “Digging Into Dilemmas of Pragmatic Clinical Trials.“ The 2-day workshop, hosted by...
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For National Rural Health Day, learn about our innovative pragmatic trials embedded in healthcare systems serving rural and remote populations: • AIM-CP • APA-SM • ARBOR-Telehealth • BeatPain Utah • LungSMART • RAMP https://t.co/oberWkv865
#PowerOfRural #PragmaticTrials
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Two new studies from the NOHARM trial explored the perspectives of patients and nurses on the implementation of a perioperative nonpharmacologic pain care education program. #nihHEALinitiative Learn more ➡️ https://t.co/yD0Nju7VFV
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📣 In this week's PCT Grand Rounds, Laura Galuchie of @Merck and Zak Smith of @TuftsCSDD will share insights informing strategies for optimizing clinical trial data collection. Join us! #pctGR 🔗 https://t.co/pD94wO8fN2
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In a new analysis from the OPTIMUM trial, researchers studied the prevalence and co-occurrence of chronic overlapping #pain conditions among patients with chronic #LowBackPain. Learn more ➡️ https://t.co/yiOPcBBWXr
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🎥 Check out our new learning module on using real-world data from routine clinical care in pragmatic trials, including patient selection, intervention delivery, and outcome ascertainment. Learn more ➡️
rethinkingclinicaltrials.org
The NIH Pragmatic Trials Collaboratory launched a new learning module video, Lessons Learned From Implementing a Pragmatic Trial Using EHR and Other Real-World Data. The video explores opportunities...
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📣 In this week's PCT Grand Rounds, Mark Siedner of @harvardmed will discuss IMPACT-BP, a community-based intervention for sustainable blood pressure control. Join us! #pctGR 🔗 https://t.co/YXTxBtXnxD
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We're thrilled to welcome 2 projects to our portfolio of innovative pragmatic trials: CARNATION and EquiP PC. Both are supported by @NIH_NINDS through the #nihHEALinitiative to improve pain management and address the national opioid crisis. Learn more ➡️ https://t.co/Lc64yE4ine
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Kudos to 2 of the newest NIH Collaboratory Trials for beginning enrollment! 👂🏼 APA-SM 🏥 iPATH Learn about these innovative #pragmatictrials embedded in healthcare systems: https://t.co/9BEsWWKvHz.
rethinkingclinicaltrials.org
Two of the newest NIH Collaboratory Trials have begun enrollment. Congratulations to the study teams from APA-SM and iPATH for reaching this important project milestone! APA-SM is enrolling patients...
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📣 In this week's PCT Grand Rounds, @pach_dr and Stefanie Lysk of @ChariteBerlin will discuss EMMA: a remote, decentralized trial to evaluate the effectiveness of a migraine app. Join us! #pctGR 🔗 https://t.co/i3eoEDTnZM
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Join experienced investigators from the NIH Pragmatic Trials Collaboratory to learn essentials of dissemination and implementation in #pragmatictrials in our full-day workshop at @academyhealth's 18th Annual D&I Conference. #DIScience25 Register today! https://t.co/dH5X2luolk
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