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Center for iPS Cell Research and Application, Kyoto University
京都 京都市 左京区
Joined April 2016
This research has been published in Nature Communications. Read the full paper with open access here.
nature.com
Nature Communications - Thymic epithelial cells (TECs) are essential for T cell development but how they develop from progenitors in humans is difficult to study. Here authors set up an in vitro...
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Professor Yoko Hamazaki and Assistant Professor Yann Pretemer have developed a groundbreaking in vitro model that faithfully recapitulates human thymic epithelial cell development using iPS cells. 🧫🔬. CiRA News 📰.🔗
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A video introducing Professor Yasuhiro Takashima's laboratory has been uploaded on the CiRA YouTube channel.
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They emphasize the importance of individualized immune monitoring and highlight the need to develop cost-effective tools to detect early immune responses. Altogether, these insights pave the way for safer and more accessible stem cell therapies.
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A research team led by Dr. Asuka Morizane, revealed the clinical safety and immune tolerance of the transplanted cells under moderate immunosuppression, regardless of HLA compatibility. URL: #iPSC #ParkinsonsDisease #RegenerativeMedicine #CellStemCell
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The CiRA research buildings will be closed from August 12, Tuesday, to August 15, Friday. Thank you for your understanding.
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Professor Shinya Yamanaka, an ambassador for the Expo 2025, visited the “PASONA NATUREVERSE” pavilion 😊���. He observed the “iPS Heart,” a cardiac tissue sheet generated from iPS cells 🫀👀
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This research has been published in the scientific journal Cell Reports Methods. Read the full paper here:. #researchpaper #CellReportsMethods #iPScellresearch.
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A research team led by Prof. Takuya Yamamoto and Asst. Prof. Ryusaku Matsumoto has developed a machine learning model that enables early prediction of hypothalamus–pituitary organoid formation from human iPS cells. #iPScells #organoids #AI #research
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The CiRA Genome Analysis Group will hold a 2-day Bioinformatics Workshop on August 26 and 27, 2025. 🧬 The event features hands-on training with PacBio HiFi data and AWS cloud-baised workflows. For details and registration:.
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This study was published in Blood Advances.
ashpublications.org
Key Points. LIN28A regulates platelet production through the let-7 microRNA-RALB axis in human iPSC-derived megakaryocyte cell lines.STAT1 modulates LIN28A
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Dr. Chen and Dr. Eto's team identified STAT1 as a key transcriptional regulator that enhances platelet production from iPS cells by epigenetically controlling LIN28A and its downstream let-7-RALB axis. Read more: [.#iPSCells #Platelets #Research #STAT1
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🎉 Celebrating 20 Years of iPS Cells!.Join us in Kyoto, Jan 26–29, 2026 for Keystone Symposia:.“20 Years of iPSCs: Past, Present, and Future” 🧫.Sessions on AI, organoids, T-CiRA, cell therapy & more. Registration now open!.🔗 #iPSCs #StemCells #Kyoto2026
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This system allows researchers to explore how quiescent epicardial tissue can be reactivated during cardiac repair. This study was published in Nature Communications on July 1st.
nature.com
Nature Communications - Producing mature epicardium in vitro could allow better understanding of cardiac tissue regeneration. Here, the authors describe how inhibition of mTOR signaling during...
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A team led by CiRA Associate Professor Yoshinori Yoshida and Antonio Lucena‑Cacace, Associate Professor at Osaka University, has created a first‑class cellular platform comprising mature epicardium and mature heart organoids. #iPSC #CardiacResearch.
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This study was published in Nature Aging on July 11.
nature.com
Nature Aging - Through non-cell-autonomous functions, senescent cells can induce secondary senescence in bystander cells. Sogabe et al. generate mouse models of MEK1- or MKK6-induced senescence and...
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A research team led by CiRA Prof. Takuya Yamamoto has developed a novel in vivo system that reveals how senescent cells behave in living tissues and influence aging through complex, heterogeneous mechanisms. #CellularSenescence #Aging.
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山中伸弥教授が出演する新番組「知的探求フロンティア タモリ・山中伸弥の!?」が、7月12日（土）19:30から、NHK総合にて放送されます。今回は「AIは人間を超えるか？」について、山中教授がタモリさん、吉岡里帆さんとともに語ります。ぜひご覧ください。.
nhk.jp
タモリさん、ノーベル賞科学者・山中伸弥さん、俳優・吉岡里帆さんが、知られざる世界との出会いをとことん楽しみ尽くします！今回のテーマは「AIは人間を超えるか」。
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The science café "Creating a Healthier You with iPS Cells and Next-Gen Medicine" was held at EXPO 2025 Osaka on June 21-22. Co-hosted by CiRA, CiRA Foundation, Institute for Regenerative Medicine at the University of Zurich, and Wyss Zurich. Read more:
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The CiRA Reporter features “Challenges in Treating Incurable Pulmonary Diseases Using iPS Cells.” We spoke with Professor Shimpei Goto about drug discovery research using alveolar organoids and the mechanisms by which SARS-CoV-2 infects the lungs.
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