Charlie Lay
@CharlieLay13
Followers
48
Following
17
Media
0
Statuses
4
GSK iCASE PhD student in Pharmacology at the University of Nottingham
Nottingham, England
Joined February 2021
Read this recent article from @SteveH025 @CharlieLay13 & others in @CellChemBiol "Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET" #BPS2022
cell.com
Lay et al. measure the binding of TAMRA-labeled IL-23 to NanoLuciferase fused receptor subunits, revealing a high-affinity binding site formed from a heteromer of IL23R and IL12Rβ1. NanoBRET was also...
0
4
14
I'm happy to share our new paper on the development of an intracellular assay for compound residence time. Thank you to all the scientists at GSK who helped with this especially Kelly Gatfield and Pete Craggs! https://t.co/WrsLUWHPny
2
2
13
Online now! Development of an intracellular quantitative assay to measure compound binding kinetics https://t.co/qRDY9tYHDD
#chembiol
0
2
7
Online now! Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET https://t.co/tJL7Stwb6v
#chembiol
0
2
8