🔬💡There's gold in them there proteins!.Can the reductive power of proteins purify gold from waste and seawater?. 👉 Read the story here:. #Biotech #MaterialsScience #PODS #UrbanMining #Nanotechnology #ProteinEngineering #GoldRecovery #CircularEconomy

🚀 Next-Gen Organoids Meet PODS® Smart Growth Factor Delivery 🧬. ✅ Long-lasting growth factor signalling.✅ Enhanced survival under stress.✅ Stronger expression of stemness markers (Nestin, CD166).✅ Superior response to injury cues . 🔗

Generating EV microRNA sequence data can be a technically challenging process. However, with the right workflow, backed up by easy-to-use kits from Cell Guidance Systems and Revvity, it becomes routine. Read more at:. #microRNA #extracellularvesicles

CAR-T in solid cancer? . With over 170 companies undertaking almost 2000 projects, CAR-T research is booming. But a myriad of challenges face CAR-Ts in solid cancers. Can they work? Find out more in our weekly blog. #CAR-T

PROTACs: Degrading can be good. Our informative weekly blog explores a technology that is bringing more drug targets into sight.

Double minutes are tiny chromosome-like structures associated with cancer that can generate uncontrolled increases in oncogene copy numbers. Read more in our weekly blog.

Dependencies can be vulnerabilities. Does cancer's dependency on macrophages create a vulnerability?.

Using Softwell, a recent study has highlighted the importance of matrix elasticity in prostate cancer. Read more in our weekly blog.

Building better bone marrow models. A recent study from Glasgow University describes a bone marrow model that may help to design improved CAR-T cells and guide target selection. Read more in our weekly blog.

How diet and the gut microbiome influence prostate cancer progression. The benefits of a good gut microbiome go beyond the gut and can impact the course of diseases, such as prostate cancer, in other organs. Read more in our weekly blog.

Parkinson's cell therapy survival agent. Recent reports of iPSC-based cell therapy for Parkinson's disease may indicate a therapeutic breakthrough. Second-generation cell therapies may benefit from cell survival agents to support implanted cells.

The central role of TAMs in cancer. Tumour-associated macrophages (TAMs) play a key role in the genesis and aetiology of cancer. Unsurprisingly, TAMs are also in the crosshairs of experimental and approved cancer therapies.

Better Nerves for regenerative medicine. Nerve conduits improve the growth of nerves across injured tissue. Using sustained-release nerve growth factor PODS improves their performance.

Immune cell boot camps in tumours may explain the abscopal effect. Read more in our weekly blog.

A better understanding of immune evasion is leading to promising new therapeutic strategies. A recent paper highlights the importance of reactive oxygen species, mitochondria and IL-10 secretion from macrophages in generating immune evasion.

Why is CAR-T cell therapy so expensive?. The cost of many therapies, including CAR-T, excludes widespread adoption. Here, we examine why CAR-T is expensive, strategies to reduce cost, and alternatives being developed.

Genetic modification and expansion of cells for autologous therapy, such as CAR-T cells, is expensive and carries a heavy regulatory burden. High efficiency reprogramming of immune cells with protein has the potential to revolutionize onco-immunology.

EVs and mental health disorders: a step towards a better understanding?.Our weekly blog explores the potential impact of EV research on the development of diagnostics and therapeutics for major depressive disorder.

Cancer is a battle between our immune system and aberrant groups of cells. CAR-T cells have shown the utility of autologous cell therapy. Monocytes are key immune cells which bloom into macrophages to orchestrate the immune system. Can they turn the tide?.

Modelling the ECM. The extracellular matrix provides a scaffold for cells, as important for our tissues and organs as the skeleton is for our body. Our weekly blog provides a beginner's guide and highlights the use of PeptiGel for modelling the ECM.