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CDKL5 Alliance Fr

@CdklFr

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Following
89
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48

France
Joined July 2017
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@CdklFr
CDKL5 Alliance Fr
5 years
Journée mondiale cdkl5. Vidéo des familles françaises. #CDKL5 #CDD #epilepsie
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@CdklFr
CDKL5 Alliance Fr
5 years
Aujourd'hui c'est la journée mondiale des maladies rares. Une balade à son rythme, ou autre pour soutenir notre association: https://t.co/erVPd3SeDu #cdkl5 #yeswename #rarediseaseday
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@CdklFr
CDKL5 Alliance Fr
5 years
⚡️ Lundi 8 février 2021, journée internationale de l’épilepsie. 📊 L’épilepsie est une maladie neurologique chronique. La plupart des enfants touchés par le trouble CDKL5 souffrent de crises d’épilepsie qui commencent dans les 8 premiers mois de vie. #CDKL5 #EpilepsyDay
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@CNSdrughunter
Ana Mingorance
5 years
Wonderful news!! EMA approves fenfluramine for the treatment of Dravet syndrome in patients 2 years of age and older. The official marketing authorisation is issued by the European Commission by the end of the year. https://t.co/ccxMfyuaBu
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@MarinusPharma
Marinus
5 years
We are humbled to be awarded The LouLou Foundation's Company Making a Difference Award – Clinical in recognition of the first successful recruitment of a pivotal and international clinical trial and recent positive data from our #MarigoldStudy.
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@MarinusPharma
Marinus
5 years
A milestone day for Marinus and the #CDD community, we are thrilled to announce results from our Phase 3 #MarigoldStudy for children and young adults with CDKL5 Deficiency Disorder. Full $MRNS top-line results: https://t.co/GPZTWv9iTv
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@PatientIntv
Heidi Grabenstatter
6 years
Join us for the 5th International #CDKL5 Family Education & Awareness Conference. - Benefit begins at 8:00 PM ET Tonight - Fri.- Sat.: broadcasting to YouTube Live and FB! Details at https://t.co/BPxukamVkI -Find livecast agenda here : https://t.co/R2xk8TWPdv
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@NoInvisibles
RarasNoInvisibles
5 years
El investigador del @IBECBarcelona, @ciberned, Arnau Hervera contribuye a una nueva vía para identificar tratamientos para una enfermedad rara conocida como Síndrome por deficiencia #CDKL5 #CDD Avances en Tto. #EERR #366diasdeEERR En @CatVanguardista👇 https://t.co/FO9zTKRdHe
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@CNSdrughunter
Ana Mingorance
6 years
Press release:
@CNSdrughunter
Ana Mingorance
6 years
Super good news for #CDKL5 deficiency disorder, we got a new ICD-10 diagnostic code that will start in October. If your #RareDisease does not have an ICD-10 code and you want to apply for one see how we did it: https://t.co/ErQBKHiery
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@AledoNeuro
Ángel Aledo-Serrano
6 years
Encefalopatía epiléptica relacionada con #CDKL5. Infradiagnosticada, y actualmente con ensayos clínicos específicos. Queda mucho por divulgar para disminuir la brecha diagnóstica. Compartimos la presentación pdf que tuvo lugar en la Reunión de Familiares: https://t.co/UiA7o42Han
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@CNSdrughunter
Ana Mingorance
6 years
Here are the news about therapy development for #CDKL5 that we learnt at the #CDKL5Forum - not an ultra-rare disease - 4 trials and much more in development - gene therapy, gene editing and X reactivation - the voice of the patient and more... https://t.co/BINyCrQ4tD
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@CNSdrughunter
Ana Mingorance
6 years
Correction!: session 3 at the #CDKL5forum was not over and we just saw the 4th CDD mouse study showing preclinical efficacy with a new drug. The drug (a PDE10A inhib) is being developed by Takeda and already got an orphan drug designation by FDA. A lot is coming up for #CDKL5!
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@CNSdrughunter
Ana Mingorance
6 years
Session 1 at #CDKL5forum, learning about #CDKL5 protein function: It controls the neuronal “skeleton” and therefore the plasticity of synapses. This can be measured in blood tests! We also learned about a promising drug that fixes that skeleton and is therapeutic in CDD mice.
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@CNSdrughunter
Ana Mingorance
6 years
We are starting the first day of the #CDKL5forum, when the #CDKL5 community comes together to review the state of the field. Representation from patient groups from 13 countries plus the @CDKL5Alliance!! And over 30 companies in the room.
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@AledoNeuro
Ángel Aledo-Serrano
6 years
#Sleep disturbances are one of the main features of #CDKL5 deficiency disorder (CDD). Dr Cao hightlights some important correlations between preclinical and clinical data. Another field to be aware of for non-epilepsy clinical trial outcomes. #CDKL5forum
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@CNSdrughunter
Ana Mingorance
6 years
Attention #CDKL5 community! the Loulou Foundation now has a FaceBook account. If you also use FB make sure you follow it to not miss any news👇🏼 https://t.co/JWteV2iYb2
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@AledoNeuro
Ángel Aledo-Serrano
6 years
Según este estudio, el 25% (un cuarto!) de los niños con epilepsia que empiezan con < 3 años tienen epilepsias genéticas consideradas “raras” (SCN1A, PCDH19, CDKL5...). Conclusión: Ya no sabemos si son tan “raras” o que no se diagnostican. @CNSdrughunter gracias por compartirlo
@CNSdrughunter
Ana Mingorance
6 years
‼️ Large genetic sequencing of all children with #epilepsy before 3 years of age: - It affects 2% of all kids - In 1 out of 4 cases they found a genetic cause: #SCN1A #KCNQ2 #GLUT1 #CDKL5 #PCDH19 and more -These "rare" syndromes are NOT so rare! Article: https://t.co/SIs49zhKa0
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