Carl McCombe 🌿
@Carl_McCombe
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PhD graduate from @BiologyANU. Studying plant-microbe interactions in the Williams lab.
Canberra, Australian Capital T
Joined December 2018
RT @Demirer_GozdeS: I am very honored to get this recognition of “Rising Stars in Plant Sciences” 🌟🌱Thank you so much @MPlantPCom and all D….
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I've had a great week @ipmb2024 in Cairns and the highlight was meeting the brilliant @Demirer_GozdeS. I'm incredibly excited to join the Demirer lab.
First time in Australia for the International Congress on Plant Molecular Biology! . Fascinating country and a conference, plus I’ve got to finally meet the future Demirer lab postdoc @Carl_McCombe in person for the first time!!. Thank you so much @neenamitter for the invitation!
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RT @biorxiv_plants: The leucine-rich repeat receptor kinase QSK1 is a novel regulator of PRR-RBOHD complex and is employed by the bacterial….
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RT @NewPhyt: Effector-triggered susceptibility by the rice blast fungus Magnaporthe oryzae. 📖 Research review by Ol….
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RT @MeganOutram91: Our new preprint is out! Alphafold2 couldn’t do it so we solved the structure of the Pgt effector AvrSr27! 🔥Spoiler: it’….
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Crosstalk between salicylic acid signaling and the circadian clock promotes an effective immune response
biorxiv.org
The rotation of Earth creates a cycle of day and night, leading to predictable changes in environmental conditions. The circadian clock synchronizes an organism with these environmental changes and...
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RT @s_vanBoerdonk: Very excited to share our story about the role of strigolactones during blast fungus infection in rice! Special thanks t….
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RT @NewPhyt: #TansleyInsight Interplay between cell-surface receptor and intracellular NLR-mediated immune responses. Jiorgos Kourelis. 📖 h….
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RT @OswaldoValdesl: Arbuscular mycorrhizal fungi inhibit necrotrophic, but not biotrophic, aboveground plant pathogens: a meta‐analysis and….
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We also investigate MoNUDIX localisation, and demonstrate that MoNUDIX-like effectors are used by pathogenic Colletotrichum species. This work was a collaboration between @williams_simonj lab at @BiologyANU, Oliveira-Garcia lab @LSU, and Schaffrath lab at @RWTH 5/5.
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Inositol pyrophosphates (PP-InsPs) signal phosphate availability in plants. We show that producing MoNUDIX in plants induces phosphate starvation responses and suppresses immune responses. Here is our current model explaining MoNUDIX’s function. 4/5
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We determined the structure of MoNUDIX to help characterise enzymatic activity. We show that MoNUDIX hydrolyses eukaryotic signalling molecules called inositol pyrophosphates. 3/5
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We generated gene knockout and complementation mutants in the blast fungus Magnaporthe oryzae and demonstrate that a secreted enzyme called MoNUDIX is important for promoting disease in rice and barley 🌾 2/5
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🚨 NEW PREPRINT 🚨. Phosphate starvation promotes interactions between plants 🌱 and beneficial microbes🦠. We describe how pathogenic fungi can trick plants into activating phosphate starvation responses to promote disease. A summary 🧵 1/5
biorxiv.org
Phosphate availability modulates plant immune function and regulates interactions with beneficial, phosphate-providing, microbes. Here, we describe the hijacking of plant phosphate sensing by a...
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RT @hailingj1: Three postdoc positions available in my lab at University of California Riverside immediately. Two are on RNA trafficking be….
iigb.ucr.edu
We post available positions from our IIGB-affiliated members and departments. If you are an IIGB member and would like to post a job, please contact [email protected]. For Campus employment opportu...
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Thanks @PiperProteins for the insightful Blender workshop at @BiologyANU, looking forward to spending more time with @bradyajohnston's Molecular Nodes. Here is AvrM14 (8DP9) from
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Excited to share our publication out now in @NewPhyt! Flax rust effector AvrM14 is an mRNA decapping enzyme capable of interfering with plant immune signalling pathways. Read more at
nph.onlinelibrary.wiley.com
See also the Commentary on this article by Banfield, 239: 7–9.
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