WHO designates JN.1 as separate COVID-19 variant of interest
As part of its announcement today, the WHO recommended universal masking for health facilities and protection for health workers.
Photo: PAHO/Flickr cc
Smart people first in line for COVID-19 vaccines, study suggests
A total of 80% of the most intelligent people were vaccinated within 40 days of
#COVID
-19 vaccine availability, compared with 180 days for those with the lowest cognitive ability.
Study finds 27% rate of long COVID in infected health workers
Multiple
#COVID19
infections were predictive of developing
#LongCOVID
Photo: Hospital Clinic / Flickr cc
Study notes high rate of COVID-infected healthcare workers still caring for patients
Half of all HCWs with symptomatic
#COVID19
continued to go to work, even if they were involved with direct patient care
Wastewater sampling in Canada suggests COVID case rate 19 times higher than reported
Sampling suggested that
#Omicron
#COVID19
cases were up to 19 times higher than reported because of changes in clinical testing
COVID Omicron carries 4 times the risk of death as flu, new data show
#Flu
was tied to 7,851 deaths from week 33, 2022, to week 12, 2023, compared with 32,607 deaths tied to
#COVID19
Study of Novavax
#COVID19
vaccine estimates 100% efficacy against hospitalizations
A post hoc analysis of a randomized, controlled trial estimates that 2 doses are 100% effective against hospitalization by 95 days
Study shows infants exposed to COVID in utero at risk for developmental delay
At 12 months, 20.3% of COVID-exposed children and 5.9% of the controls received a diagnosis of neurodevelopmental delay.
Joshua Rappeneker / Flickr cc
COVID study: 40% of children still infectious after symptom resolution
The median time to symptom resolution was 6 days, and 12% of participants still had symptoms at day 10.
SARS-CoV-2 can damage mitochondrion in heart, other organs, study finds
Mitochondrial dysregulation leads to long-term damage and may help explain long COVID, the authors say.
1 in 4 COVID survivors had impaired lung function 1 year on, study shows
Of all patients, 11%, 22%, and 48% of those with mild, moderate, or severe
#COVID
-19, respectively, had impaired lung function.
Photo: mr.suphachai praserdumrongchai / iStock
COVID-19 tied to dangerous blood clots in cancer patients
The risk of developing venous thromboembolisms is elevated among cancer patients with
#COVID19
taking anticancer drugs, new data show
Studies: Dogs can detect COVID-19 with greater than 80% sensitivity
A review of 27 studies reveals that dogs have more than 80% sensitivity and more than 90% specificity for detecting
#COVID19
in people through scent
Study: 1 in 6 kids have persistent COVID symptoms for 3 months after infection
A review of 31 studies reveals that
#LongCOVID
affects 16% of children and adolescents after
#COVID19
Study: Regardless of variant, half of long-COVID patients fail to improve after 18 months
The analysis included 806 patients who were infected with the wild-type strain, Alpha, Delta, or Omicron strain.
SARS-CoV-2 can infect coronary arteries and trigger heart attack, stroke, study suggests
The researchers found
#SARS
-CoV-2 viral RNA in coronary atherosclerotic plaques in all patients—regardless of the extent of plaque buildup.
Using both nose, throat swabs boosts sensitivity of rapid
#COVID
testing
The findings suggest that US rapid antigen testing recommendations should include throat specimens.
Photo: Banc d'Imatges Infermeres, Ariadna Creus/Angel Garcia / Flickr cc
US government failure to protect frontline workers from
#COVID
led to thousands of deaths, scientists say
CDC guidance was based on droplet dogma rather than the current view that SARS-CoV-2 spreads primarily through aerosols, the authors said.
US reports more
#H5N1
#AvianFlu
detections in mammals
Species include skunk, raccoon, bobcat, red fox, grizzly bear, black bear, tiger, and mountain lion
Study shows COVID leaves brain injury markers in blood
Researchers looked at blood levels of serum inflammatory proteins (cytokines), antibodies, and brain (neuroglial) injury proteins.
Study suggests higher risk of new-onset
#post
-COVID autoimmune, autoinflammatory disorders
Relative to controls, COVID-19 patients had significantly higher risks of conditions such as alopecia areata, alopecia totalis, Crohn disease, and sarcoidosis.
Tests confirm avian flu on New Mexico dairy farm, probe finds cat positives
The virus was also confirmed on five more Texas farms, as investigators find more clues from animal samples and genetic sequences.
COVID's aftermath: Persistent organ damage at 1 year, lung abnormalities at 2
Of all participants, 59% had organ damage at 1 year—even those with non-severe infections
#LongCovid
#COVID19
Study: Death rates in COVID ICU patients 69% higher than for flu
#COVID19
patients had a longer hospital stay and a 69% higher mortality rate than ICU patients with influenza, national French data show
Researchers identify type of long COVID with persistent inflammation
About 60% of
#LongCOVID
patients had signs of persistent inflammation, including elevated neutrophil activation, while recovered and uninfected participants did not
#COVID19
The much-awaited first report in our "COVID-19: The CIDRAP Viewpoint" series has just been published: "The future of the COVID-19 pandemic: lessons learned from pandemic influenza" lays out several potential
#pandemic
scenarios
#COVID19
#coronavirus
Study links air quality improvements to fewer school COVID cases
The study took place at a school that serves vulnerable students in a setting where air quality improvements were made and then monitored.
Study shows dogs can detect COVID-19 faster, better than most PCR tests
Studies show that dogs can detect asymptomatic people, those who had
#LongCOVID
, and new
#COVID19
variants
COVID-19 infection associated with type 1 diabetes in kids
The incidence of new-onset type 1 diabetes was almost double in kids diagnosed as having
#COVID19
Some kids, teens have long-term lung damage after
#COVID19
MRI reveals lung damage in children who either had COVID-19 up to a year earlier or who have
#LongCOVID
Sepsis associated with COVID-19 infections more common than thought
Overall, SARS-CoV-2–associated sepsis was present in 28.2% of patients admitted with SARS-CoV-2.
COVID-19 behind thousands of excess US deaths, analysis shows
A total of 162,886 of these excess natural-cause deaths (90% PI, 14,276 to 308,480) were not reported as COVID-19.
Study: Kids with COVID but no symptoms play key role in household spread
The clinical secondary attack rate (SAR) for asymptomatic positive children was 10.6%.
Patients with COVID-19 at time of heart attack have more clotting
Clots were seen in multiple arteries in close to 30% of patients with
#COVID19
at the time of their heart attack, but in less than 5% of heart-attack patients who did not have COVID-19
New breath test shows promise for rapid COVID-19 detection
The test provided no false results, with accurate results obtained after 2 breaths for each participant
Photo: Chakrabarty lab / Washington University
#COVID19
may trigger new-onset high blood pressure
While the exact cause of hypertension is unknown, it is possible that SARS-CoV-2 causes cardiac dysfunction and blood pressure dysregulation via the ACE2 receptors
COVID tied to higher risk of inflammatory autoimmune diseases for 1 year
#COVID
-19 patients were at a 25% to 30% increased risk for new-onset inflammatory autoimmune diseases after the first 30 days post-infection.
Study: Cats can transmit COVID-19 to each other
Cats can become infected with
#COVID19
through contact with other infected animals or contaminated surroundings, the data show
Photo: Thryn / Flickr cc
FDA greenlights Novavax's updated COVID vaccine
The FDA's announcement paves the way for people to start receiving the vaccine at pharmacies and doctor's offices.
Photo: Courtesy of Novavax
Asthma patients report worse asthma control after COVID-19
People with asthma experienced worse control of their asthma after they had recovered from mild to moderate
#COVID19
WHO continues global polio emergency as breach noted at Dutch vaccine facility
Virus was detected in a sewage sample and was genetically similar to stocks used at the lab, then a lab worker tested pos
Photo: IAEA Imagebank, Dejan Vidanovic / Flickr cc
Less than 5% of US preschool cohort hospitalized for
#COVID
were fully vaccinated, study finds
Most critically ill children were unvaccinated or hadn't completed their primary series.
Cancer patients with COVID at higher risk of death, hospitalization amid Omicron
The 30-day death rate after
#COVID
-19 diagnosis was twice as high in the cancer group than in controls.
Decline in COVID reporting muddles tracking of global illness patterns
Amid reduced testing and case reporting, hospitalization and death trends may be more reliable COVID activity markers.
Photo: NIAID/Flickr cc
Not 'little adults': Experts say
#long
COVID undercounted, misdiagnosed in kids
Experts say it could be better defined and measured through well-designed longitudinal studies that take children's unique presentations into account.
Codagenix announces promising findings for intranasal COVID vaccine
Earlier this month, the company received a contract from Project NextGen, a federal effort to deliver new treatments and vaccines.
Study: 1 in 7 Americans have had long COVID
Americans who report having experienced long COVID said they also experienced more anxiety, low mood, and difficulty with memory.
Blood donor study finds 21% incidence of long-term symptoms attributed to COVID-19
Among blood donors with prior SARS-CoV-2 infection, 23.6% reported long-term neurologic symptoms
COMMENTARY: Wear a respirator, not a cloth or surgical mask, to protect against respiratory viruses
2 papers say surgical masks and respirators r no different in preventing spread of respiratory diseases like
#COVID19
and
#flu
, but they are deeply flawed
Study estimates 1.4 million deaths shortly after 'zero COVID' ended in China
A new analysis estimates that 1.41 million
#COVID19
deaths occurred in the 35 days following the relaxation of China's policy
WHO elevates XBB.1.16 to variant of interest as levels rise in US and other countries
The subvariant could spread globally and fuel increased cases, due its growth advantage and immune escape properties.
Photo: NIAID/Flickr cc
CDC releases ventilation guidance for curbing indoor respiratory virus spread
Advice includes optimizing HVAC systems and other steps to improve air quality and circulation.
Photo: Adam Winsor/Flickr cc
Experts say CDC not getting right advice on hospital infection prevention
The guidance is meant to protect both healthcare workers and patients.
Department of Defense, Reese Brown / Flickr cc
Severe
#COVID
-19, death lowest by far among vaccinated Canadians
The unvaccinated were 11 to 17 times more likely to die than those who completed a primary COVID-19 vaccine series.
Feds launch indoor air quality research program
The group is looking for research proposals on indoor air biosensors, respiratory virus risk assessment software, and optimizing building controls.
Photo: Michael Casey/Flickr cc
Study: China saw almost 2 million excess deaths just after zero-COVID policy ended
Researchers use obituary reports to estimate that 1.87 million excess deaths occurred in the first 2 months after the policy lifted
#COVID19
‘A deadly societal force’: Q&A with Peter Hotez on the
#anti
-science movement
Some call it misinformation, but Hotez dislikes that term "because it implies that it's just some random junk on the internet. It wasn't that at all."
Photo: Michael Stravato
#LongCOVID
patients with severe fatigue report little relief by 20 months
Only 7 of the 55 patients (13%) in the severely fatigued group saw improvement in their physical impairments over time
#COVID19
Study: Vaccinated patients have lower risk of long COVID
At 90-days post-infection, 8% of vaccinated cases were still reporting symptoms, compared with 27% of unvaccinated cases.
Photo: Blake Patterson / Flickr cc
Evolving peak
#SARS
-CoV-2 loads relative to symptom onset may influence home-test timing
Median SARS-CoV-2 viral loads rose from symptom onset, peaking on the fourth or fifth day of symptoms.
Quick takes: Novavax COVID vaccine effectiveness, COVID booster uptake, avian flu in two states
Over a 4-month period, protection with the Novavax vaccine was stable against symptomatic COVID infection.
Birth records show COVID-19 caused spike in preterm births
The study suggests the US vaccination campaign likely prevented thousands of preterm births
Amber McNamara/flickr
Higher mortality seen in patients with COVID-19, Pseudomonas coinfection
Researchers observed a 44% greater adjusted risk of mortality in patients with Pseudomonas aeruginosa bloodstream infection and COVID-19 coinfection.
Risk of death 3 times higher in Brazilian kids with
#COVID
-19 than with other respiratory viruses, study finds
Estimated odds of in-hospital death by 30 days was 7% for COVID-19 and 2% for flu.
Study shows 43% to 58% lower prevalence of long COVID among vaccinated people
The prevalence of 30-day long COVID was 43% lower among the vaccinated group
Paxlovid tied to 30% lower risk of severe COVID in patients with chronic conditions
Subgroup analysis found significant benefits for patients with cancer, cardiovascular disease, or both.
Nearly two thirds of Korean SARS-Cov-2 cohort had long
#COVID
at 2 years
The most common symptoms at 2 years were fatigue, memory loss, trouble concentrating, and insomnia.
CDC continues to receive reports of MIS-C in kids following COVID infections
The CDC said the cases are a reminder that vaccination is an important tool for preventing MIS-C, which can be severe or even fatal.
Almost a third of
#COVID
survivors report symptoms 2 years post-infection
The most common long-COVID symptoms were fatigue, cognitive impairment, and pain.
Photo: Frerieke / Flickr cc
Study: COVID wastewater signals more accurately predict hospitalizations
Australian researchers developed a model that predicted hospitalizations, which could give facilities 1 to 4 weeks to prepare for influxes.
Updated WHO
#COVID
prevention guidance may endanger rather than protect, some experts say
In a case of "droplet dogma," the
#WHO
hasn't fully recognized the role of aerosols in the transmission of respiratory viruses, they say.
Canada detects poliovirus in wastewater samples
The CDC is testing the Canadian samples to see if they are genetically related to poliovirus samples from New York
#polio
Avian flu virus detected in more Michigan dairy herds and on another large layer farm
Along with multiple detections now in dairy cows, avian flu has also hit two massive layer farms in the state.
Photo: F.D. Richards/Flickr cc
Study on masks vs N95 respirators for health workers spurs concerns
The findings suggest medical masks may offer similar protection as N95 respirators against
#COVID19
, but experts say hold on
Study: Cognitive slowing is associated with long COVID
More than half (53.5%) of patients with PCC had a response speed slower than 2 standard deviations from the control mean.
Analysis finds positive risk-benefit for Novavax COVID vaccine
A drop in overall infections, hospitalizations, and deaths outweighed the risk from rare reports of myocarditis or pericarditis.
Photo: Novavax
Novavax
#COVID19
vaccine 80% effective among US teens
Vaccine effectiveness against the Delta variant, the only strain identified through whole-genome sequencing, was 82.0%
Photo courtesy of Novavax
Florida reports 2 locally acquired malaria cases
Officials confirm that the cases are caused by the Plasmodium vivax
#malaria
parasite, which is not as fatal as other malaria species
Study: Infection-control measures stemmed
#COVID
spread in hospitals from 2020 to 2022
Most transmission occurred in the community and households and when universal masking wasn't followed, the authors said.
Photo: US Navy, Ryan M. Breeden / Flickr cc
Vaccines cut risk of
#post
-COVID heart failure, blood clots for at least 6 months, data suggest
Effectiveness against heart failure and blood clots in the veins and arteries was 22%, 53%, and 45%, respectively, in the month after SARS-CoV-2 infection.
Pre-infection COVID vaccination linked to lower odds of lingering symptoms
Pre-infection
#COVID19
vaccination was tied to a lower likelihood of persistent symptoms 45 days after infection
#LongCOVID
Type A blood linked to higher rate of
#COVID19
infections
Moreover, the study shows the spike protein's affinity for type A cells may be amplified by the
#Omicron
strain of the virus
Photo: biologycorner / Flickr cc
Many Americans who lose taste, smell over
#COVID19
don't fully recover
Following infection, 24% had partial and 4% had no no smell recovery, while 21% had partial and 3% had no recovery of taste
More than 70% of US household COVID spread started with a child, study suggests
Pediatric
#COVID19
transmission was negatively correlated with new community cases during most of the pandemic, new data show
COVID survivors with depressive, cognitive symptoms show signs of brain inflammation
Patients with persistent symptoms of brain impairment after mild to moderate
#COVID19
had elevated levels of a protein indicating inflammation
#LongCOVID
Meta-analysis reveals high rates of heart complications in
#long
-COVID patients
The estimated prevalence of chest pain and abnormal heart rhythms was 10% and 8%, respectively.
Help us get answers from
@YouTube
, as we wait for a resolution! Our Osterholm Update podcast episode (Jul 22) was removed for “medical misinformation.”
@mtosterholm
advocates FOR vaccines & does not spread misinformation. We know this was a mistake & want the video back up ASAP!
WHO grants emergency listing for Corbevax COVID vaccine
Non-exclusive licensing of the yeast strain by developers will allow others to develop effective, low-cost vaccines.
Photo: Texas Children's Hospital
Large study shows safety of
#COVID19
mRNA vaccines in young children
Medical records were searched for 23 serious potential vaccine side effects, including blood clots, seizures, stroke, and myocarditis
Photo: Quinn Dombrowski / Flickr cc