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Kennedy McDaniel Bae | BioOptimist Profile
Kennedy McDaniel Bae | BioOptimist

@BioOptimist

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inveterate BioOptimist | PhD | humanist | BAE.eth | love/live w/ @lwsnbaker

New York City
Joined November 2015
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
Read "The Moral Imperative to Teach AI" to see how educators will determine whether GenAI becomes pernicious or a panacea:
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
Each year without proper AI instruction is another generation paying the price through diminished cognitive development. But Educators face a challenge: how do you teach something you haven't been trained in yourself?.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
It will take decades to acquire data on the impact of GenAI on long-term cognition and dementia. But, let’s be honest, we know some of the consequences:. Reduced cognitive utilization → long-term cognitive decline → increased risk of dementia.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
All of this is compounded by the fact that AI-generated explanations are compelling by design. So compelling that people trust AI reasoning over their own—even when the AI is wrong and they are correct.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
For professionals, using AI means shifting from being the creator to the reviewer. The problem is you still think you retain the ability to create. For students, it’s similar but worse. They miss out on the opportunity to effectively judge the boundaries of their knowledge.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
The evidence is already clear: AI affects learning, reasoning, critical thinking, creativity, and metacognition—our ability to regulate our own thought processes. How we use this tool defines how it changes our cognition.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
When you use GPS constantly, your spatial cognition weakens. When you rely on Google, you remember how to find info rather than the info itself. AI takes this adaptation to a new level because it changes how we think.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
4 months
What if we replaced "How do we keep AI out of the classroom?" with "How do we teach AI as a tool rather than a crutch?".
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Check out the full post exploring the future of biological research, automation, and the hidden forces shaping our experiments here:
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Automating cell culture isn't about making science easier - it's about making it better. By acknowledging rather than denying natural selection in our labs, we're opening new frontiers in biological research.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Automating cell culture isn't about making science easier - it's about making it better. By acknowledging rather than denying natural selection in our labs, we're opening new frontiers in biological research.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
As labs modernize and bring in automation, there's an opportunity to do better. We need to rethink cell culture from the ground up, just like the alarm clock reinvented wake-up calls. Enter: self-driving cell culture systems.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
As labs modernize and bring in automation, there's an opportunity to do better. We need to rethink cell culture from the ground up, just like the alarm clock reinvented wake-up calls. Enter: self-driving cell culture systems.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
This problem has been known for over 50 years, yet most labs still avoid regular cell verification. Some argue time and cost, but fundamentally it's a workflow problem.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
This problem has been known for over 50 years, yet most labs still avoid regular cell verification. Some argue time and cost, but fundamentally it's a workflow problem.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
In part because of the mechanisms of selection at play, 5-46% of cell lines in research labs are misidentified. Even samples from originating labs are wrong 18% of the time. We're often not working with what we think we are.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
In part because of the mechanisms of selection at play, 5-46% of cell lines in research labs are misidentified. Even samples from originating labs are wrong 18% of the time. We're often not working with what we think we are.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Biologists face a paradox: they want to minimize variability to more easily analyze their results, BUT they are studying systems that evolved to have high variability as an evolutionary survival strategy.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Biologists face a paradox: they want to minimize variability to more easily analyze their results, BUT they are studying systems that evolved to have high variability as an evolutionary survival strategy.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
So point 1 - natural selection and survival of the fittest takes place EVERYWHERE, including experimental labs.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
So point 1 - natural selection and survival of the fittest takes place EVERYWHERE, including experimental labs.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Take HeLa cells as an example. Did you know these immortal cells are so good at surviving that they literally invade other cell lines?. One study found that 67% of misidentified cells had been overtaken by HeLa cells.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Take HeLa cells as an example. Did you know these immortal cells are so good at surviving that they literally invade other cell lines?. One study found that 67% of misidentified cells had been overtaken by HeLa cells.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
High school bio told you about the peppered moth and it's changes due to pollution during the industrial revolution. Lab specimens are doing the same thing under our noses, but the consequences for research are far more complicated.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
High school bio told you about the peppered moth and it's changes due to pollution during the industrial revolution. Lab specimens are doing the same thing under our noses, but the consequences for research are far more complicated.
@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Natural selection doesn't just happen in nature - it's actively shaping laboratory experiments (and sometimes undermines them).
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Natural selection doesn't just happen in nature - it's actively shaping laboratory experiments (and sometimes undermines them).
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Prediction 3: New statistical approaches will .1) attempt to quantify and measure the probability of validity .2) assess the resiliency of the proposed model .3) assess the resiliency of the biological system .4) result in numerical-based assessments of modulatory impact.
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@BioOptimist
Kennedy McDaniel Bae | BioOptimist
6 months
Prediction 2: The structure of hypotheses will change, rejecting the model of a single null and alternate hypotheses pair searching for causality in favor of .1) exploring the number of alternate hypotheses explored .2) increased focus and sensitivity to modulatory effects.
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