📢This study describes clonal #heterogeneity at unprecedented levels. Capturing spatially resolved DNA sequences from intact tissue sections authors show that clonal populations are confined to distinct spatial regions. ⁦⁦@Nature⁩ Tweet added by Giampaolo Bianchini @BianchiniGP

Giampaolo Bianchini

2 years

📢This study describes clonal #heterogeneity at unprecedented levels. Capturing spatially resolved DNA sequences from intact tissue sections authors show that clonal populations are confined to distinct spatial regions. ⁦⁦ @Nature ⁩

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues

Nature - A technique using barcoded beads for DNA sequencing within tissue sections enables spatial resolution of tumour clonal heterogeneity and can be multiplexed with other analytical techniques...