
Baker Institute OAR
@BakerResOAR
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A feed of the latest research publications from the Baker Heart and Diabetes Institute. Our main Twitter account is https://t.co/reRzrIDlHV
Australia
Joined June 2019
Exercise blood pressure in adults with high-risk left ventricular hypertrophy: the importance of normalizing blood pressure to oxygen uptake .
pubmed.ncbi.nlm.nih.gov
The greater EEBP incidence in LVH using traditional thresholds reflects differences in resting BP, not an exaggerated SBP response. Therefore, those with high-risk LVH have a normal SBP response to...
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Lymphatic uptake and pharmacokinetics of lipid conjugated brush PEG polymers is altered by interactions with albumin and lipoproteins .
pubmed.ncbi.nlm.nih.gov
Overall, administration with albumin and altering lipoprotein trafficking pathways modified the biodistribution and lymphatic uptake of the polymers, supporting that they traffic into lymph in...
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Association of Pericoronary Adipose Attenuation With Major Adverse Cardiovascular Events and High-Risk Plaque .
pubmed.ncbi.nlm.nih.gov
Although the strength of associations varied by measurement technique, PCAT is associated with MACE and high-risk plaque.
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Editorial: Targeting the interleukin-1β/interleukin-6/C-reactive protein pathway in clinical medicine - a road map to clinical trial design .
pubmed.ncbi.nlm.nih.gov
Editorial: Targeting the interleukin-1β/interleukin-6/C-reactive protein pathway in clinical medicine - a road map to clinical trial design
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Cancer control measures have prevented 230,000 deaths in Australia since the mid-1980s .
pubmed.ncbi.nlm.nih.gov
These estimates demonstrate the value of sustained cancer control investment, particularly in primary and secondary prevention.
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Familial clustering of diabetic kidney disease and retinopathy in offspring of parents with type 1 diabetes: a population-based study .
pubmed.ncbi.nlm.nih.gov
Folkhälsan Research Foundation, Medical Society of Finland, Wilhelm and Else Stockmann Foundation, Finnish Diabetes Research Foundation, Waldemar von Frenckell Foundation, Liv och Hälsa Society,...
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Clinical management of diabetic cardiomyopathy with insights into pathophysiology and diagnosis .
pubmed.ncbi.nlm.nih.gov
Diabetes mellitus is associated with significant morbidity and premature mortality for which heart failure (HF) is a major cause. HF may be due to ischaemia, hypertension, valvular disease, uraemia,...
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Multiparity induces persistent myocardial structural, functional and transcriptomic remodelling in mice .
pubmed.ncbi.nlm.nih.gov
Pregnancy poses unique hemodynamic and metabolic demands on the heart. Recent data suggests that a history of multiple pregnancies may be associated with a late-term increased risk of heart failure...
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Annexin-A1 deficiency uncovers female-specific pathways in blood pressure control and cardiovascular remodeling in mice .
pubmed.ncbi.nlm.nih.gov
Cardiovascular disease exhibits distinct sex-based differences, yet the mechanisms underlying these differences remain under-explored. The pro-resolving mediator annexin-A1 (ANXA1) is a pivotal...
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Relationships of Cognitive Function With Subsequent Device-Measured Physical Activity and Sedentary Time in Healthy Individuals and Those With Bipolar Disorder: Findings From the UK Biobank .
pubmed.ncbi.nlm.nih.gov
The current study provides preliminary evidence that cognitive function may influence subsequent physical activity and sedentary time similarly in those with BD and healthy controls; however, further...
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Determinants of temporal change in telomere length and its associations with chronic complications and mortality in type 2 diabetes: the Fremantle diabetes study phase II .
pubmed.ncbi.nlm.nih.gov
In adults with type 2 diabetes, rTL does not always shorten over time. rTL and ∆rTL were associated with baseline conventional cardiometabolic risk factors but not independently with major incident...
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Letter to the Editor: Quader M, Kiernan Z, Labate G, Chen Q. Hypothermic myocardial preservation: the freezing debate. Transplant Proc. 2025;57(4):653-662. Fear of Freezing Fallacy: Storage in Melting Ice Cannot Damage the Donor Heart .
pubmed.ncbi.nlm.nih.gov
The recent report by Quader et al (Quader M, Kiernan Z, Labate G, et al. Hypothermic myocardial preservation: the freezing debate. Transplant Proc. 2025;57(4):653-662) addresses a critical question...
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Emerging evidence and potential avenues to achieve durable outcomes in patients with obesity: the confluence of nutrition, and Microbiome on body composition .
pubmed.ncbi.nlm.nih.gov
Obesity is a global health concern that impacts health, quality of life, and longevity in affected individuals. Comorbid cardiovascular disease, type 2 diabetes, cancer, and other conditions often...
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Supine Blood Pressure and Cardiovascular Risk .
pubmed.ncbi.nlm.nih.gov
Supine Blood Pressure and Cardiovascular Risk
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Variation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort .
pubmed.ncbi.nlm.nih.gov
The spread of antibiotic-resistant bacteria has severely reduced the efficacy of antibiotics and now contributes to 1 million deaths annually. The gut microbiome is a major reservoir of antibiotic...
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Trajectory of plasma lipidome associated with the risk of late-onset Alzheimer's disease: a longitudinal cohort study .
pubmed.ncbi.nlm.nih.gov
The National Health and Medical Research Council of Australia (#1101320 and #1157607); NHMRC Investigator grant (#GNT1197190); Victorian Government's Operational Infrastructure Support Program;...
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Variation in uptake of sodium glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor analogues in adults with type 2 diabetes at high cardiovascular risk .
pubmed.ncbi.nlm.nih.gov
Prevalent use of SGLT2i and GLP-1RA was suboptimal and varied across clinical characteristics and behavioural risk factors. While some variation reflects complexities in prescribing for this older...
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No evidence from euglycaemic-hyperinsulinaemic clamp studies for greater insulin sensitivity in adults with type 1 diabetes using insulin pump versus multiple daily insulin injections-Post hoc meta-analysis .
pubmed.ncbi.nlm.nih.gov
No evidence from euglycaemic-hyperinsulinaemic clamp studies for greater insulin sensitivity in adults with type 1 diabetes using insulin pump versus multiple daily insulin injections-Post hoc...
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Including Indigenous knowledge in biomedical research: a co-autoethnography .
pubmed.ncbi.nlm.nih.gov
National Health and Medical Research Council of Australia and National Heart Foundation of Australia.
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