The prevalence of high 10-year CVD risk among the general adult population in Malaysia is high. Lower education level, sleep inadequacy, physical inactivity, and fatty liver are independent factors...

Omega-3 FAs have a positive effect on macrovascular outcomes, muscle metabolism and health, specifically in clinical populations. The direct effects of omega-3 FAs on muscle microvascular outcomes in...

False advertising is a long-term problem, but, with modern technology, it is now possible to create rapidly and inexpensively and widely distribute fake video, audio and written social media presen...

This study highlights distinct long-term adherence patterns among individuals with T2DM, with over half showing non-persistent use over a five-year period, falling into either early discontinuation...

Echocardiography is the gateway to appropriate therapy for many cardiovascular diseases, but access to this test is sometimes challenging. The consequence is that patients in rural and remote areas...

Many physical health triage tools exist, most solely for dietetics, with heterogeneous characteristics and application outcomes. Updated tools are needed for triage to exercise/physical rehabilitat...

Anatomical variants, such as May-Thurner syndrome (MTS) and inferior vena cava (IVC) variants, are underrecognized causes of deep venous thrombosis (DVT), despite affecting management. We aimed to...

Compared with people without cancer, cancer survivors have a higher risk of subclinical cardiac dysfunction. However, dysfunction is less common with increasing time since cancer diagnosis. These...

The global prevalence of type 2 diabetes has risen sharply in recent decades, with significant regional and demographic variation. While high- and middle-income countries generally report a higher...

Heart failure presents a critical health challenge with a 5-year mortality rate of up to 50%. Conventional treatments often lead to bradycardia or hypotension due to their impact on patient hemodyn...

Galectin-3 (Gal3) is known to interact with glycans of proteins and lipids. In cardiovascular disease, the elevated expression of Gal3 mediates inflammation, hypertrophy and fibrosis. We explored the...

Impaired cholesterol homeostasis is a major factor contributing to the development and progression of atherosclerosis. Previous studies have shown that metformin, the first-line antidiabetic therapy,...

CRP does not activate T Cells directly but via PI3-kinase-dependent activation of monocytes and subsequent CD80/CD28 cell to cell contact. The findings suggest the effects of CRP on T cells depend on...

Peptide biology is a fascinating subject, and peptide pharmacology even more so. Peptides have multiple bodily functions, including their work as hormones and metabolic modulators. However, certain...

The responsibility, and right, of promoting metabolic health, and preventing metabolic disease, is that of the primary care physician. This communication lists the facets of metabolic care in a...

Coping with chronic disease, such as obesity, is central to effective management. Coping skills enhancement, therefore, should be made part of obesity therapy. The AEIOU model, coupled with the five...

Obesity is been acknowledged to be a major risk factor for chronic kidney disease (CKD), contributing to both its onset and progression. Over past few decades, the obesity epidemic has lead to an...

Screen use has been associated with poor cognitive and mental health, yet few studies have examined its effects on brain activity. Our aims were to describe changes in brain activity and mood states...

Renal denervation (RDN) is an adjunct therapy for resistant hypertension, reducing blood pressure (BP) by inhibiting both afferent sensory and efferent sympathetic renal nerve activity. The resulting...

Embryo development involves fertilization of a mature ovum, which, after sequential cell divisions (2-,4-8-cells and morula), undergoes differentiation into implantation competent blastocyst. The...