Cell Proliferation
@BISCRM
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An open access journal publishing research in all aspects of cell proliferation and differentiation in normal and abnormal states. Flagship journal of CSSCR.
Beijing
Joined June 2023
Piezo2 is the principal mechanosensitive ion channel governing touch, proprioception, and systemic homeostasis, with emerging therapeutic potential as a druggable target for mechanotransduction-related disorders.
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"A stylish woman in a beige coat walking confidently past a moving train at a modern train station.". Create images and videos in seconds with Grok Imagine.
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Pioglitazone suppresses mitochondrial excessive ROS generation and COX-2 level through inhibition of Drp-1 mediated mitochondrial fission in an AMPK-dependent manner in LS.
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Maternal TCF12 ensures female fertility by regulating oocyte competence, fertilization, and preimplantation development through cortical granule organization and PP2A-mediated cell cycle control.
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ROCK1 inhibition rescues TBI-induced cognitive deficits by restoring hippocampal neurogenesis through the ROCK1-AKT signaling axis.
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PTRF-mediated caveolae formation promotes BRAF inhibitor resistance in melanoma by upregulating EGFR signaling.
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PIK-III enhances cuproptosis in resistant renal cancer by restoring thiamine metabolism, redirecting glycolysis into the TCA cycle, and synergizing with elesclomol to induce metabolic crisis.
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Kdf1 regulates molar cusp formation by controlling dental epithelial cell proliferation via the PI3K/AKT/mTOR pathway.
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Despite mouse-specific amino acid changes in Cdx2's DNA-binding domain, its transcriptional effects remain conserved between rodents, revealing evolutionary plasticity in TF binding but stability in gene regulation.
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ITGB2 promotes osteoclast differentiation in osteoarthritis via Rac1 activation, and its inhibition slows disease progression by suppressing bone resorption, revealing a potential therapeutic target.
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FAM20A insufficiency disrupts gingival fibroblast function, leading to gingival overgrowth in AI1G through altered cell adhesion, differentiation, proliferation, and apoptosis.
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Welcome to join the 17th HOPE Young Scientist Forum online at 14:00 (GMT+8) on July 31 via Tencent Meeting forward to the excellent talks! 🥳Host: Dr. Qiutan Yang @QiutanYang
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MFG-E8 worsens abdominal aortic aneurysms by increasing oxidative stress via the ERK/NOX4 pathway, while resveratrol counteracts this effect, suggesting potential treatment benefits.
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This study created a reliable mouse model of melasma using UVB, progesterone, and stress, which mimics human melasma and responds to tranexamic acid, offering a tool for future research.
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CLEC3A, PCDH10, and ST3GAL1 promote endocrine resistance in ER+HER2− breast cancer via PI3K-AKT signaling, offering prognostic and therapeutic targets.
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ROCK2 inhibition enhances osteosarcoma sensitivity to MPPa-PDT by suppressing autophagy via the Hippo pathway.
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Welcome to join the 16th HOPE Young Scientist Forum online at 21:00 (GMT-4) on May 23 via Tencent Meeting forward to the excellent talks! 🥳Host: Dr. Guihai Feng. Speakers: Dr. Dong Han, Dr. Xin Tang @XinTang288269 and Dr. Haijiao Liu @haijiao_liu
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GSN+ inflammatory fibroblasts impair immunotherapy response by exhausting CD8+ T cells, with a new Caf.Sig model predicting outcomes and suggesting GSN boosting as a combo therapy.
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Targeting RBM39 attenuates BER via destabilising OGG1 mRNA and potentiates KBrO3-induced oxidative stress in HCC.
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