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Institute of Biophysics of the Czech Acad. Sci. Profile
Institute of Biophysics of the Czech Acad. Sci.

@BFUavcr

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Center for Medical Research

Brno
Joined November 2020
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
4 hours
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
4 hours
New study alert🚨Z-DNA isn’t just a structural curiosity-it’s a regulatory player. Using ChIP-seq data,researchers identified 22candidate Z-DNA–binding proteins,including TP53,MAX & CREB1. Z-DNA is enriched in active genomic regions,hinting at its role in transcriptional control.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
1 day
Gratulujeme Oddělení molekulární biofyziky a farmakologie! 📷 Srdečně blahopřejeme kolegům z Oddělení molekulární biofyziky a farmakologie k uveřejnění jejich nového vědeckého článku. Přejeme mnoho dalších úspěšných publikací!
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
7 days
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
8 days
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
9 days
Join us for an inspiring scientific discussion with one of the leading researchers in the field of DNA replication.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
9 days
We warmly invite you to the upcoming IBP lecture by Prof. Aga Gambus, who will share her latest insights into the mechanisms of genome duplication and its role in maintaining genome stability.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
10 days
We sincerely thank this year’s speakers, Roberto Fernandéz, Monika Čechová, Clément Lafon Placette, and Ondřej Hovorka, for sharing their valuable experiences and insights. The event was made possible thanks to the generous support of EMBO!
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
10 days
The event offered an inspiring program of career talks, round-table discussions, and networking opportunities, bringing together students, postdocs, and researchers from research institutes across the Brno region.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
10 days
On November 7th, 2025, our institute hosted the fourth IBP Career Day: Per Aspera Ad Astra.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
10 days
These findings show how oxygen tension tunes nitro-fatty-acid bioactivity and point to precision therapeutic strategies for oxidative-stress-related diseases. https://t.co/bYA6LgmP2f
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
10 days
Nitro-oleic and nitro-linoleic acid isomers—unlike the saturated nitro-stearic analogue—stabilized and translocated NRF2 and robustly induced Hmox1/HO-1 and Gclm/GCLM, with activity dependent on nitro-group position and double-bond configuration.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
10 days
Our colleagues at Palacký University in Olomouc developed a streamlined two-step synthesis that delivers ultrapure, regio- and stereodefined nitro-fatty acids; using these, we reveal oxygen-dependent control of NRF2 stabilization in mouse bone marrow cells.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
13 days
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
14 days
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
17 days
Tyto spletité útvary hrají významnou roli v procesech spojených se stárnutím buněk a vznikem nádorů a mohou být klíčem k vývoji nových léčiv či diagnostických metod. #ČeskáHlava #CenaLorem #VědaProZdraví #Gkvadruplexy #DNAvýzkum #Biomedicína
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
17 days
Cenu Lorem, určenou pro oblast zdravotnictví, obdržela Michaela Dobrovolná z Vysokého učení technického v Brně (PhD studentka prof. Václava Brázdy) - za výzkum nekanonických struktur DNA, takzvaných G-kvadruplexů.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
17 days
Den otevřených dveří v BFÚ.
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@BFUavcr
Institute of Biophysics of the Czech Acad. Sci.
20 days
Publikace je výsledkem dlouhodobé badatelské práce celého týmu a potvrzuje vysokou úroveň výzkumu, který se na našem ústavu v této oblasti rozvíjí. Srdečně gratulujeme autorům a přejeme mnoho dalších úspěchů ve výzkumu!
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