Asish Das Gupta
@Asish_Dasgupta
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Cell Biologist and a proud father
Kingston, Ontario
Joined January 2018
Impaired mitochondrial fusion allows growth of abnormal cells: PINK1‐induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation & promotes cell proliferation in lung cancer & pulmonary arterial hypertension @QueensuDOM
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Mitochondrial division (mitotic fission), due to excess Drp1 & MiD49/MiD51, regulates cell cycle progression in cancer https://t.co/3QUjcmTxVX. Targeting this new epigenetic mechanism to treat cancer @QueensuDOM @KingstonHSC @queensuResearch. Note fragmented mitos in cancer cell
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Inhibiting mitochondrial division (mitotic fission), by MiD49/MiD51 knockdown, causes fusion & cell cycle arrest in cancer https://t.co/3QUjcmTxVX. Targeting new epigenetic mechanism to treat cancer @QueensuDOM @KingstonHSC @queensuResearch. c/w last tweet: now mitos are fused
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