Asaf (Klaf) Weisman
@AsafKlaf
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PhD candidate at @TelAvivUni. Researcher of the spine and people experiencing pain. MSK Physiotherapist and 👇🏻 philosopher wannabe blog
Omnipresent
Joined June 2017
Officially published💥 A reboot to the pain field! The aphorism that “nociception is neither necessary nor sufficient for pain” has caused a lot of damage to patients and set back the field. This paper was not easy to publish and was rejected by all the major pain journals for
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A long-awaited and requested update of Painlosophy. I added a "table of contents" or a quick access list of past blogs, along with a search window function. I will do a few more modifications and improvements in the upcoming weeks https://t.co/cBFVtynWwU
painlosophy.wordpress.com
Visit the post for more.
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💥Interesting new study indicates that multilevel abnormalities in Lumbar MRI correlate with an inflammatory phenotype of low back pain. The inflammatory phenotype = •Morning stiffness (≥30 min, <4 hours) •Improvement with exercise •Worsening with rest •Waking from pain
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Evidence that hypothalamic inflammation precedes obesity and type 2 diabetes! As the hypothalamus is central to energy and glucose regulation, this means that changes in the function of glia and astrocytes may be key determinants that later amplify brain and peripheral feedback
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“Opioid Induced Hyperalgesia” (OIH) is another concept that is sccepted as “FACT” in the pain field and it couldn’t be further from that. It is also used as an excuse to deny opioids from patients, and to tell them stories about how it can “change their pain system”, and as of
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Opioid induced analgesia is yet another assumptive construct in pain medicine that has turned into “fact”. It is nothing but a marginal phenomenon and is now being used by nitwits to prevent opioid treatment.
Did you know not only is the false claim made that we have evidence that Opioid Induced Hyperalgesia is common in chronic pain pts on opioids, several KOL claim that OIH is the root cause of most chronic pain itself? That the whole reason we have chronic illness could actually be
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A new review of preclinical and clinical evidence about the anti-inflammatory effects of GLP agonists. The research quality around this drug class is unparalleled, and I think we are barely scratching the surface of understanding about the importance, benefits and potential of
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đź’ĄThis is really exciting and fascinating, with implications that cannot be understatedđź’Ą Researchers have developed an antivenom effective against 18 different snake species, paving the way toward a universal synthetic antivenom! They immunized an alpaca and a llama to generate
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“The mess created by one fool cannot be corrected by even 100 wiseman”! It’s going to take a long time to rid society from this nonsense. See also Brandolini’s asymmetry principle of Bulls**t: “The amount of energy needed to refute bullshit is an order of magnitude bigger than
@AsafKlaf @EFIC_org Psychological pain does exist as the brain is required for pain. language, belief and psychological factors are involved in and affect pain and are the best interventions.
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There are several misconceptions and assumptions in the #pain and #neuroscience fields that have no foundation: 1. All nociceptive mechanisms have been discovered, and therefore, any unexplainable pain, and mainly many chronic pain states fall into psychological/brain “origin”
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Logic is the basis of science. All of quantitative science is basically A vs. B testing and building advancements upon existing FACTS. There are rules to logic and you can learn them. Our 2020 paper gives an introduction into logical thinking and arguments which are powerful
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The aphorism “nociception is neither necessary nor sufficient for pain” complicated and compounded the pain field, and sent it on a side quest. By ditching this aphorism and accepting the necessity of nociception, defined broadly as an activation of an apparatus, we can start
Officially published💥 A reboot to the pain field! The aphorism that “nociception is neither necessary nor sufficient for pain” has caused a lot of damage to patients and set back the field. This paper was not easy to publish and was rejected by all the major pain journals for
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The race for a “vaccine” for obesity is ON in the biomed industry. And we seem closer than ever to achieving that! This company developed a special GLP analogue that together with special gene therapy that makes the muscles generate a special protein, allows their analogue to
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Breaking news and some simple rules to live your life by: ✴️Not all opinions are created equal. ✴️You do not deserve your own facts. ✴️Your own facts, opinions and beliefs do not make others ignorant. ✴️Refuting your OPINIONS and BELIEFS with logical arguments is not
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The cardiovascular risk decrease of GLP drugs is independent from weight loss! This likely due to the systemic anti inflammatory effect of GLP. We are really just at the tip of the GLP iceberg. There is so much undiscovered potential for this drug class.
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Following my posts where I claimed that psychological interventions are ineffective for chronic pain, someone pointed me to this systematic review where it is shown that short-term psycodynamic treatment is effective for chronic pain with a large effect ~0.7. Now, this is an
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It’s really interesting how people cling to psychosocial stress as an important cause of pain and chronic pain. And I say IT DOESN’T MATTER! And especially nowadays. Why? Because we have no good way to predict who is it risk and intervene early. Can we move a person who was
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