Ang Zhou
@AngZhou3
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Research associate at MRC biostatistics unit @Cambridge_uni; Adjunct research fellow @UniversitySA
Cambridge, England
Joined August 2018
I drew this hedgehog with mathematical equations.
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Metabolic profile predicts incident cancer: A large-scale population s... https://t.co/755QJlemes
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@ACPreH1 @sahmriAU Very excited to share our recent publication - Vitamin D Deficiency Increases Mortality Risk in the UK Biobank.
New #research from @UniversitySA shows that #vitamin D deficiency is associated with premature #death, prompting calls for people to follow healthy vitamin D level guidelines. #health
https://t.co/nFrIqAxVIo
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Excited to share this work, and so proud to be working with such a great team! @anwarmulugeta2 @ACPreH1 #basalmetabolicrate #dementia #brainiron
World-first #research from @UniversitySA's @ACPreH1 has found a link between #metabolism and #dementia -related #brain measures, providing valuable insights about the disease. https://t.co/mSt4FdP6tE
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Five Feynman rules for Life: 🧠 i) Take mistakes as Lessons. ii) Focus is the key. iii) Study hard what interests you the most. iv) Don't worry about what other people think. v) Skills are more valuable than your grades
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Flying Among Birds in France with Christian “Birdman” Moullec
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The difference between a good student and a great one is that a good student is concerned more about the outcome while a great one is fascinated by the process of learning.
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Our genetic analyses provide supporting evidence that low vitamin D status can contribute to chronic inflammation, measured by elevated C-reactive protein @ACPreH1
If you're low on Vitamin D, you could be at risk of #inflammatory diseases such as #type2diabetes or #heartdisease, according to world-first #research from @UniversitySA
https://t.co/TyFSIKvUVf
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Cannot agree more on this.
Giving a science talk that few people understand does not make you look smart and does not help you. #AcademicTwitter #phdchat #phdlife #scicomm
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A few years ago, I would not have the courage to be active on Twitter because I would allow the "haters" to define who I am. Nowadays, I tell myself that the ones who see my worth are the ones who matter. The ones who don't are missing out. #SaturdayThoughts #selfcompassion
Yesterday, someone commented how my advice is harming people. Then they blocked me. How does that make me feel? Curious. Empathetic. Would I have felt that way a year ago? No. Twitter can bring out the worst in us, but it also lets us practice being who we really want to be.
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Association of #Lifestyle and #Genetic Risk With Incidence of #Dementia @JAMA_current #ExeterDementia @ElaKuzma @alzassociation @turing @NIH @uk_biobank @EPSRC @UniofExeter @ExeterMed
jamanetwork.com
This cohort study uses UK Biobank data to examine interactions between polygenic risk for Alzheimer disease and lifestyle (physical activity, healthy diet, moderate alcohol drinking) and their...
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Also, stratifying individuals according to their polygenic scores from the interaction model and showed notable differences in the effects of lifestyle on cardiovascular risk across stratified groups, implying the need for individualizing lifestyle changes for CVD prevention
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A Whole-Genome Approach Discovers Novel Genetic and Non-Genetic Variance Components Modulated by Lifestyle for Cardiovascular Health https://t.co/SxcodUBLcM
#biorxiv_genetic
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Is the link between more years in education and lower rates of smoking causal? And is it due to general cognitive ability, or education per se? It appears that it's education itself - new study in @NatureComms by @ECSanderson
https://t.co/uplJZE2Kxc
@BristolTARG @mrc_ieu
nature.com
Nature Communications - Higher educational attainment is positively associated with a number of health outcomes. Here, Sanderson et al. use multivariable Mendelian randomisation analysis to test...
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+1 Even when target known from human genetics, super hard to make new medicines Gene/disease: CFTR/cystic fibrosis Discovery: 1989 Medicine: 2012 @VertexPharma G/D: FBN1/Marfans Discovery: 1991 Medicine: not yet G/D: PCSK9/MI Discovery: 2003 Medicine: 2015 @Regeneron @Amgen
Rare monogenic disease is a great example where targets are or should be completely clear; yet to date truly impactful, life-altering therapies are far fewer and far between than would have been predicted. Speaks to significance of other challenges.
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