ATUM
@ATUM_bio
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Bioengineering ingenuity for a better world.
Newark, CA
Joined August 2009
Transient HEK or stable pool CHO? E. coli or Pichia? 10ml or a liter? With industry leading SPEED, QUALITY & EFFICIENCY, our integrated process takes your order from expert *in silico* design to purified protein & analytics under one roof. 👉 https://t.co/iYTuMUJ1se
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Is RNA sequence design set to revolutionize #DrugDiscovery like codon optimization did in the early 2000s? Claes Gustafsson says 'Yes,' in his @medicine_maker opinion piece. Discover how this innovation is transforming RNA drug economics & methodologies:
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Miss us at this year's #BPIEast? Check out @GENbio's coverage of Oren Beske's talk on how ATUM's Leap-In® Transposon platform is shaking things up in cell line engineering! Dive into the details here: https://t.co/wwBOn657Pv
#CellLineDevelopment #DrugDiscovery
genengnews.com
Making complex proteins and unique biological entities is getting increasingly complex. A generalized CHO host may not be the best way to go.
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Join the discoCHO™ craze! Celebrate ATUM's CHO-K1 platform with our Spotify playlist of 20 Disco classics, perfect for grooving in the lab or on the dance floor.🕺 Come play(list) with us! ▶️ https://t.co/MFUcGSdVzl
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TODAY at #PEGSEurope: Groove into the world of 'Engineering mAb-Like Molecules: From Leads to Drugs' with Claes Gustafsson. Catch the beat today at 15:20 CET. And don't just stand there—boogie on over to Booth #1318 to get the lowdown on our latest chart-topper, discoCHO™!
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Looking for be-spook life science tools & solutions this Halloween? đź‘» ATUM's got you covered! Our trick: A fully integrated ecosystem powered by state-of-the-art machine learning. Your treat: Attaining your scientific goals in less time & for less money. https://t.co/94qnd0FUVy
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Fibrosis is a response to chronic injury. Leads to tissue scarring + organ failure. Nice paper by @MorphicTx use Fab from @ATUM to get xtal structure of integrin αvβ6, a promising drug target against fibrosis. Find MORF-627, a highly selective inhibitor https://t.co/2XQguZxnw9
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NEW in @LabManager🚨From HEK293 to CHO cells, ATUM's Claes Gustafsson explores the cutting-edge methods making #biologics dominant in today’s pharmaceutical market. https://t.co/kSp6lVislJ
#CellLineDevelopment #DrugDiscovery
labmanager.com
From HEK293 to CHO cells, learn about the cutting-edge methods making biologics dominant in today’s pharmaceutical market.
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This #WorldFoodDay, we're proud to be the engineering team behind CHY-MAX® Supreme, an enzyme that enables cheesemakers to produce more cheese from the same amount of milk. From increasing safety to sustainability, ATUM is proud to support the efforts of those feeding the world.
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Leishmania causes 40k deaths/yr. Biggest parasitic killer after malaria. @uiowa @NIUlive @seattlechildren @SSGCID @UnivOfKansas @NYSBC_Science use @ATUM_bio constructs. Identify single Leishmania enzyme generates acetyl-, acetoacetyl-CoA. Great drug target https://t.co/2l2lXHMvx6
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Pichia is the industry workhorse for yeast recombinant protein production. @BOKUvienna #ACIB @LonzaGroup use @ATUM_bio constructs to build a methanol-free induction system with 7-fold higher secretion using PG1 promoter and flo8 deletion https://t.co/daT6M27JLC
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Drug-resistant SARS-CoV2 selects for mutations in the main protease MPro. @ORNL @NIH @TNWesleyan shows how the mutations affect MPro dimer formation while retaining catalytic activity. MPro substitution constructs made by @ATUM_bio
https://t.co/7WQBHCecnz
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Fungal peroxygenases are cool enzymes for synthetic chemistry. However, they don't behave well in heterologous expression systems. @CSIC @EvoEnzyme @tudresden_de use Pichia system from @ATUM_bio to produce peroxygenase from Marasmius wettsteinii at 0.7g/L https://t.co/TTxn4SOgqB
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Ca2+ release from endoplasmic reticulum is necessary for myoblasts formation and differentiation during muscle development. @riken_en use constructs from @ATUM_bio to show that the Ca2+ signaling is mediated through Calpain-5 https://t.co/1KkNwDUCuf
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Excited to be a Gold Sponsor for the upcoming @festofbiologics! With 2 speakers lined up, we're looking forward to sharing insights on the latest in bispecifics, multispecifics, developability & analytics. Attending? Let's connect! https://t.co/3qZP4bPlt7
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👂🎧 Did you hear? ATUM has launched discoCHO™, a novel CHO-K1-based platform, for faster biologics development! Talk with one of our experts today! https://t.co/0VSB4JkAhJ
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Just at our #BPIEast presentation and want to learn more about leveraging multiple orthogonal transposases in the genetic engineering of CHO? Stop by Booth #831 in the Exhibit Hall and connect with an ATUM team member NOW! #BPIconf #CellLineDevelopment #biologics
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High fidelity DNA polymerase from Pyrococcus furiosus (Pfupol) is an attractive alternative to the popular Taq DNA polymerase. @brin_indonesia use constructs from @ATUM_bio to develop an efficient autoinduction system for Pfupol https://t.co/tIn8CDrbCw
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Mucus layer in gut protects from pathogenic bacteria. @ugent @Evonik use @ATUM_bio constructs built in in the ClosTron system to show that the chiA gene in Clostridium perfringens is a chitinase that specifically breaks down mucus to invade the host https://t.co/PXrcjIKW3u
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Liver cancer causes 12k deaths/yr in US. @OmegaTX show epigenomic mRNA leads to genomic methylation and downregulation of regulator cMYC. Causes significant reduction of liver cancer in preclinical model. DNA binding proteins made from @ATUM_bio genes.
nature.com
Nature Communications - Development of targeted MYC inhibitors for cancer therapy remains challenging. Here, the authors design an mRNA medicine which downregulates MYC gene transcription via...
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