
ASH Clinical News
@ASHClinicalNews
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A magazine from @ASH_Hematology offering news and views for the broader hematology/oncology community.
Joined October 2014
The August issue is out now! Highlights include a feature on the current state of #GeneTherapy in #hematology, meeting coverage of #ISTH25, a debate on combination therapy for #myelofibrosis, and more. Check out the full lineup here: 🩸
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Long-term research presented at #ISTH25 affirmed that CHIP has an independent negative effect on overall survival, but treatments for #CoronaryArteryDisease in patients who were CHIP-positive did not help overcome this effect:
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RT @doctorpemm: 👉👉👉Delighted to share our brand new MPN debate & article in @ASHClinicalNews @ASH_hematology | . @GabyHobbs & @doctorpemm….
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RT @WileyOnc_Hem: The Aug issue of @ASHClinicalNews is here!. This month's issue explores complex topics such as how to approach HLA typing….
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#ISTH25 Use of the EULAR 2023 criteria — developed to refine the classification of #AntiphospholipidSyndrome — was found to improve specificity compared with the 2006 Sydney criteria but resulted in decreased sensitivity, leaving many patients excluded:
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Recent research indicates that MRD-guided time-limited treatment with #zanubrutinib, #venetoclax, and #obinutuzumab resulted in deep remissions in patients with previously treated #ChronicLymphocyticLeukemia, with a best uMRD rate of 85%:
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#MentalHealth may play a significant role in #lymphoma and #MultipleMyeloma #MMsm. According to a recent study, 52% and 27.5% of adults met the diagnostic criteria for #anxiety and #depression, respectively, in the first six months after a diagnosis of lymphoma or MM.
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At seven years of follow-up, #daratumumab showed continued single-agent clinical activity in patients with intermediate or high-risk #SmolderingMultipleMyeloma with no new safety concerns, according to the final analysis of the phase II CENTAURUS study:
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Check out what's new in the July issue! Highlights include a feature on the Trump administration's impact on #hematology in its first 100 days, testing and treatment of elevated factor levels post-stroke, recent findings from #ASCO25 and #EHA25, and more:
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RT @JhaveriKhushali: 🚨Just published in @ASHClinicalNews:. What does moral injury look like in oncology? Not about being tired — but about….
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The #FDA recently approved tafasitamab in combination with #rituximab and #lenalidomide to treat #FollicularLymphoma in adults, based on findings showing a 22.4-month median PFS with the therapy compared with 13.9 months in the control arm:
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RT @WileyOnc_Hem: Research published in @haemophilia_jnl reveals that providers may be insufficiently screening — and thus undertreating —….
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Using #ctDNA, genetic subtypes of classical #Hodgkin #lymphoma were found to be driven by the mechanism of genetic instability rather than the grouping of #mutations into functional categories, according to new findings published in @BloodPortfolio:
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RT @WileyOnc_Hem: Editor-in-Chief @AaronGerds, MD, shares highlights from the July issue of @ASHClinicalNews, including a feature on the Tr….
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When used in combination with other medications, #venetoclax appears to be effective in patients with R/R #MultipleMyeloma #MMsm harboring t(11;14), with an ORR of 64%, but is less efficacious when certain other chromosomal abnormalities are also present:
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ASH Clinical News is seeking associate editors! Editors have the opportunity to share their views on topics in #hematology, participate in content development, and provide subject matter expertise. For more information and to apply by August 15, visit:
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According to findings from #EHA2025, patients with newly diagnosed #MultipleMyeloma #MMsm that was treated with Isa-KRd saw increased levels of sustained MRD negativity compared with patients treated with a combination that did not include #isatuximab:
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According to data from #EHA2025, GLPG5101, a fresh, stem-like, early memory phenotype CD19-directed #CARTcell therapy, demonstrated a manageable safety profile in patients with R/R #nonHodgkin #lymphoma, producing low rates of high-grade toxicities:
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When compared with the standard assays to assess #ADAMTS13 activity for suspected TTP, newer point-of-care rapid assays demonstrated higher diagnostic accuracy and concordance and lower rates of discrepancies: #thrombosis #ClottingDisorders #classicalheme.
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