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The American Journal of Clinical Pathology is a leading anatomic & clinical #pathology journal. 🔬@ASCP_Chicago official publication 👨‍🔬 EIC: @AJCP_EIC

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@AJCPjournal
AJCP
4 years
Hospital-based recruitment may be an efficient way to prospectively identify donors of convalescent plasma. Learn more here: #bloodbank #transfusionmedicine #COVID19
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The findings in this study highlight the need for standardized quality control protocols for ICS devices.
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AbstractObjectives. Intraoperative cell salvage (ICS) is broadly used in high-risk surgical procedures to facilitate rapid autologous red blood cell transf
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2 months
These researchers identified highly sensitive and specific exonic markers to detect mismatch repair deficiency by next-generation sequencing.
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AbstractObjective. To identify exonic markers that could improve analytic performance characteristics of next-generation sequencing (NGS) in detecting mism
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AJCP
2 months
In the June issue: Biomarkers of response to antibody-drug conjugates and the immune microenvironment in penile squamous cell carcinoma.
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AbstractObjectives. We aimed to assess the expression of biomarkers of response to antibody-drug conjugates (TROP2 and nectin-4) and immune microenvironmen
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AJCP
2 months
Primary lung salivary gland-type intraductal carcinoma (IC) is very rare; a diagnosis requires pathologic examination because of its nonspecific clinical manifestations.
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AbstractObjectives. Salivary gland-type intraductal carcinoma (IC) is a rare type of low-grade salivary gland neoplasm. Given that the clinical and imaging
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AJCP
2 months
In the June issue: Revision of interpretation criteria to define microsatellite instability in mismatch repair–deficient neoplasms with subtle electropherogram changes.
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AbstractObjectives. To improve analytic performance characteristics of a microsatellite instability (MSI-V1.2) assay in endometrial cancers (ECs).Methods.
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AJCP
2 months
Compared with conventional high-grade HER2+ breast tumors, low-grade HER2+ breast carcinomas may represent a distinct subset that could benefit from therapeutic de-escalation strategies.
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AbstractObjectives. Breast carcinomas overexpressing human epidermal growth factor receptor 2 (HER2) are typically associated with higher tumor grade and f
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AJCP
2 months
The pilot program outlined in this paper provides insight into the feasibility of a locally based and locally run PT program. Read it here:
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AbstractObjectives. To implement a pilot proficiency testing (PT) program in Accra, Ghana, using locally produced PT materials and to explore the relations
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AJCP
2 months
Over 90% of HER2 FISH group 2 to 4 breast cancers with equivocal (2+) IHC followed by targeted, blinded second FISH rescoring and final HER2-positive status have less than 50% amplified population of tumor. Learn more here:
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AbstractObjectives. To investigate the correlation between the extent of (percentage of tumor cells) immunohistochemistry (IHC) staining and final human ep
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AJCP
2 months
Open-access paper in the June issue: Coagulation abnormalities following brown recluse spider (Loxosceles reclusa) envenomation.
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AbstractObjective. Hemostatic abnormalities, including disseminated intravascular coagulation (DIC), are often cited as a common finding in patients follow
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Journal CME: Histopathologic and genetic distinction of well-differentiated grade 3 neuroendocrine tumor versus poorly-differentiated neuroendocrine carcinoma in high-grade neuroendocrine neoplasms.
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Online journal article in Molecular Pathology that offers 1.0 continuing education (CME) credit that can be used to fulfill CC Part II requirements.
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AJCP
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Journal CME: Revision of interpretation criteria to define microsatellite instability in mismatch repair deficient neoplasms with subtle electropherogram changes.
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  Online journal article in Molecular Pathology that offers 1.0 continuing education (CME) credit that can be used to fulfill CC Part II requirements.
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AJCP
3 months
In the June issue: Diagnostic utility of lymphocyte enhancer factor 1 in aggressive B-cell lymphoma with MYC rearrangement.
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AbstractObjectives. We sought to investigate the diagnostic value of lymphocyte enhancer factor 1 (LEF1) expression in aggressive B-cell lymphomas (BCL) wi
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AJCP
3 months
This review aims to assist pathologists in making an accurate diagnosis in high grade neuroendocrine neoplasms. Read it here:
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AbstractObjectives. The classification of neuroendocrine neoplasms has evolved significantly. In the current World Health Organization (WHO) classification
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AJCP
3 months
This case highlights the importance of a re-biopsy when the initial biopsy fails to explain the clinical presentation. Read it here:
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AbstractObjective. Cutaneous lupus erythematosus (CLE) is a chronic autoimmune disorder of the skin.Methods. In this report, we describe the case of an Afr
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AJCP
3 months
The necessity for haptoglobin trimester-specific RIs in the pregnant population needs to be assessed. Learn more here:
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AbstractObjectives. Pregnancy induces physiologic changes that can affect serologic and immunologic markers, potentially resulting in lower haptoglobin val
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AJCP
3 months
In the June issue: High-sensitivity KIT D816V variation analysis by droplet digital polymerase chain reaction.
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AbstractObjective. Systemic mastocytosis is a hematologic malignancy characterized by clonal expansion of neoplastic mast cells. Detection of this variatio
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