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LAST CHANCE TO APPLY!. @ACCTMTH Martin S. Wolfe Mentoring Award. Recognizing an individual who has served as an exemplary and inspiring mentor. Deadline: TODAY, June 23.

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Join Our Upcoming Webinar!. Topic: AI's Future in Tropical Medicine.Date: Thursday, June 26th.Time: 2pm EST. Speakers.✅ Dr. Kamran Khan, MD, MPH from BlueDot and University of Toronto.✅ Dr. Rie Yotsu MD, MIPH, DTM&H, PhD from Tulane School of Public Health and Tropical Medicine.

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Do you know someone in academia, clinical practice, industry, the CDC, NIH, military, or a foundation who has served as an exemplary and inspiring mentor?. @ACCTMTH is now accepting nominations for the Martin S. Wolfe Mentoring Award to honor such a mentor.

[5/5] We sincerely thank the authors of the following paper for this interesting case report: 

[4/5] Classic presentations of melioidosis include pneumonia, bacteremia, osteomyelitis, and multifocal abscesses. Treatment requires IV ceftazidime or meropenem followed by 12-weeks of oral eradication with TMP/SMX.

[3/5] Melioidosis, a bacterial infection with Gram-negative Burkholderia pseudomallei, is an uncommon cause of EN but should be considered in endemic regions (SE Asia, Australia). Diagnosis by serology/culture (Ashdown’s agar/selective broth), however cultures often negative.

[2/5] Indirect hemagglutination assay (IHA) against Burkholderia pseudomallei resulted in a high titer (>1:10,240). Patient presumptively treated for melioidosis with 5 days ceftazidime followed by 12-weeks TMP-SMX with ulcer healing (Fig F) and fall in IHA titers to 1:1,280.

[1/5] ANS: The differential diagnosis of EN includes non-infectious (drugs, sarcoidosis, pregnancy, IBD, autoimmune disease) and infectious etiologies. Streptococcus is the most common associated infection, followed by Mycoplasma, TB, Chlamydia, histoplasmosis.

[4/4] [4/4] Ceftazidime was started with resolution of fevers and nonprogression of lesions over 5 days. What is the probable diagnosis?.

[3/4] Workup included ASO, anti-DNase, mycoplasma Abs, ANA panel, ACE level, O&P, blood cultures, and CXR - all negative. Lesions worsened over 3 days developing hemorrhagic blebs (Fig B&C), contents from which were cultured but grew no organisms on MacConkey and Blood agar.

[2/4] A skin biopsy was performed showing acute inflammation of connective tissue between the fat lobes (septal panniculitis) without evidence of vasculitis, c/w erythema nodosum (EN, Fig D&E). What is the differential diagnosis of EN?

[1/4] Oct '24 Case: 14 y/o boy in Thailand with 1 week fevers and painful, erythematous nodules on lower limbs (Fig A). No sore throat, cough, weight loss. Temp 39oC, unremarkable physical exam, no lymphadenopathy.

[5/5] Aug’24 Response: We sincerely thank the authors of the following paper for this interesting case report: @ASTMH.

[4/5] Aug’24 Response: MRI may show an unspecific heterogeneous mass. Dx is made by recovery of a sparganum from infected tissue. ELISA for anti-sparganum antibodies and PCR are also used. Treatment is with surgical removal of worms. Praziquantel can be given as an adjunct.

[3/5] Aug’24 Response: Cases found mainly in China, Japan, Korea, & sporadically in Thailand. Larvae can migrate anywhere in the body. Clinical signs include painless subcutaneous nodules. CNS manifestations are pain, weakness, numbness & seizures. Cauda equina syndrome rare.

[2/5] Aug’24 Response: Sparganosis is caused by migration of plerocercoid larvae (sparganum) of tapeworm Spirometra. Humans are accidental intermediate hosts & can be infected by drinking H2O w/copepods contain. procercoid larvae or by ingesting undercooked snakes, frogs or birds.