Tyler Funnell
@tylerfunnell
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Computational Biologist
New York, USA
Joined March 2009
For those of you hunting for your next position, please consider applying for a postdoctoral position in our lab. Our science is wild and exciting, and I promise to train and feed (yes, w/free food) you well. It doesn't hurt that we are on a publication hot streak.
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Interested in developing biostatistical / machine learning tools with applications in translational cancer microbiome research? I am hiring a postdoctoral scholar @MSKBiostats! Please feel free to DM if you have questions. https://t.co/I87cDyJvWp
linkedin.com
We are hiring a postdoctoral fellow in biostatistics at MSKCC. Please feel free to share this post with potential candidates. We encourage the candidates to send application materials as instructed...
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Excited to share our R package for microbiome data analysis, published @CellRepMethods, which makes log-ratio lasso regression more accessible for R users, supporting continuous, binary and survival (competing risks) outcomes. https://t.co/YeXHzPdoBZ
https://t.co/ipBvWQl8FK
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Interested in DNA replication and genomic instability? Our new method PERT identifies S-phase cells and estimates replication timing from single cell whole genome sequencing (scWGS) data with heterogeneous copy number https://t.co/o2d8ZXlnbR 1/10
biorxiv.org
DNA replication is a highly coordinated cell cycle process that can become dysregulated in cancer, increasing both proliferation and mutation rates. Single-cell whole genome sequencing holds potent...
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My new lab at @MSKCancerCenter is recruiting a postdoc and also a computational biologist to work on #microbiome and cancer #immunotherapy. https://t.co/UOnErs4jZQ. Postdoc position linked below. compbio position soon. Please reach out. https://t.co/mqaj2GZtAS
peledlab.org
The Peled Laboratory's website promotes a scientist's research.
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My wife, Vicky, made an award-winning & touching short film "Elephant". It's about a jovial old man trying to process his Alzheimer's diagnosis while agonizing over how to protect his love from heartbreak. https://t.co/nDpJPNpfCv A love story in time for Valentine's Day 🙂
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Exciting opportunity for a Data Engineer to join the van den Brink lab at MSKCC and help us understand how gut bacteria affect cancer patients! https://t.co/iSoiVm1rpz
linkedin.com
Today's top 24,000+ Senior Data Engineer jobs in United States. Leverage your professional network, and get hired. New Senior Data Engineer jobs added daily.
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Hey everyone, for something a little different on Black Friday, I'd like to show you a no budget micro-short my wife (I helped a bit) made before the pandemic. She shot it in <4 hours with a couple of talented SAG actors! https://t.co/Y6y4BMG6Ui
#indiefilm #shortfilm #Filmmaking
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Interested in structural variant mutational processes at single genome resolution? latest preprint, product years of hard work, reveals clock-like serrate structural variants. kudos to @tylerfunnell @oflanach , everyone in @sajraparicio & @SohrabShah labs.
biorxiv.org
Structural genome alterations are determinants of cancer ontogeny and therapeutic response. While bulk genome sequencing has enabled delineation of structural variation (SV) mutational processes...
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Excited to share some new work with @sajraparicio, @SohrabShah, and teams where we looked at genomic instability at allele-specific resolution in more than 30,000 single-cell whole genomes 1/11
Evolutionary tracking of cancer haplotypes at single-cell resolution https://t.co/iiYP823v49
#bioRxiv
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Evolutionary tracking of cancer haplotypes at single-cell resolution https://t.co/iiYP823v49
#bioRxiv
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The impact of mutational processes on structural genomic plasticity in cancer cells https://t.co/TG9iBqHu13
#bioRxiv
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CellAssign from @SohrabShah and @kieranrcampbell uses a probabilistic model to leverage prior knowledge of cell-type marker genes to annotate scRNA-seq data. https://t.co/IkkHxEPyYG Read our News & Views on supervised clustering for #SingleCellAnalysis. https://t.co/p6eYjQIg0e
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Twitter friends: My lab is searching for an eccentric, excited computational postdoc/scientist to lead multimodal (metabolic, immunophenotypic, genetic) analysis in RCC and AML. Job ad coming soon, pls spread the word and come join the vibrant community @CompOncMSK @KidneyCancer
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Our method CellAssign for automatically assigning cell types from scRNA-seq data is published today Paper: https://t.co/BpJRSHcGSM R package: https://t.co/8HrJm99ODx (1/8)
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Reviewer 2 agreed that the ability to determine structures directly within the cellular environment would "transform structural cell biology" https://t.co/uLrnDXaCUZ
#fromthedecisionletter #ResearchAdvance
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New from Funnell et al. Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models https://t.co/UooInmF8d2 Part of our cross journal #MachineLearning in Health and Biomedicine collection https://t.co/KF78oZYiFH
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A new statistical framework for mutation signature discovery out today: https://t.co/kcZmPng3Y7 . Fantastic work by @tylerfunnell - integrates multiple mutation types into signature discovery with correlated topic models: relevant to cancers with DNA repair defects.
journals.plos.org
Author summary Over time DNA accumulates mutations from a variety of sources. Some mutations result from external mutagens, such as UV radiation, while others result from processes occurring within...
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A new approach for detecting somatic mutations from multi-region tumor sequencing out in @CommsBio . Lots of hard work by Fatemeh Dorri- congratulations! https://t.co/cqjYVtPcnH
#muclone
nature.com
Communications Biology - Fatemeh Dorri et al. present MuClone, a method for simultaneous detection and classification of mutations across multiple tumor samples derived from one patient. They show...
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How to classify cell types in single cell RNA-seq data without needing to cluster data up front? Use CellAssign - new method from @kieranrcampbell and Allen Zhang in the lab out today: https://t.co/o3vycBOlpI , encodes prior information for probabilistic cell-type assignment.
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