Targeted Oncology
@TargetedOnc
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Oncology news and insights from leading researchers and cancer centers.
Greater New York Area
Joined July 2012
π‘Dr. Alexa Meara illuminated opportunities for education and cross-collaboration between oncology and rheumatology in the immunotoxicity management context, emphasizing a precision medicine approach that not only targets the tumor, but also considers the patient as a whole.
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π£Weekend Read: A recent study reveals that medication burden significantly increases acute care use in older metastatic prostate cancer patients on androgen receptor inhibitors. Read the full details on our website.π
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Izalontamab shows promise as a safe treatment for advanced #epithelial tumors, demonstrating early antitumor activity in a recent #ClinicalTrial. #Oncology #Cancer
targetedonc.com
Izalontamab shows promise as a safe treatment for advanced epithelial tumors, demonstrating early antitumor activity in a recent clinical trial.
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#ESMO25: A study reveals that lower KIM-1 levels predict better outcomes in advanced #RenalCellCarcinoma patients treated with nivolumab and ipilimumab. #biomarkers
targetedonc.com
A study reveals that lower KIM-1 levels predict better outcomes in advanced renal cell carcinoma patients treated with nivolumab and ipilimumab.
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New trial results reveal sacituzumab govitecan shows promise for HR+/HER2β metastatic #BreastCancer, despite missing primary survival goals.
targetedonc.com
New trial results reveal sacituzumab govitecan shows promise for HR+/HER2β metastatic breast cancer, despite missing primary survival goals.
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πΉ WATCH: Dr. Jonathan Strosberg @MoffittNews discusses the safety profile and long-term toxicities of 212Pb-DOTAMTATE treatment, highlighting renal issues and achalasia in patients. #NANETS2025
targetedonc.com
Dr. Strosberg discusses the safety profile and long-term toxicities of 212Pb-DOTAMTATE treatment, highlighting renal issues and achalasia in patients.
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#ESMO25: New research identifies CD8+ PD-1+ TIM-3- LAG-3 TILs as promising #biomarkers for improved outcomes in metastatic clear cell #RenalCellCarcinoma treatments.
targetedonc.com
New research identifies CD8+ PD-1+ TIM-3- LAG-3 TILs as promising biomarkers for improved outcomes in metastatic clear cell renal cell carcinoma treatments.
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πΉ WATCH: Dr. Michael Soulen discusses safety concerns and adverse events in #NeuroendocrineTumor treatments, highlighting cytopenia and radiation risks while ensuring patient safety. #NANETS2025
targetedonc.com
Dr. Michael Soulen discusses safety concerns and adverse events in neuroendocrine tumor treatments, highlighting cytopenia and radiation risks while ensuring patient safety.
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#ESMO25: The DISCUS trial reveals that shorter systemic therapy improves quality of life for advanced #UrothelialCancer patients, challenging traditional treatment durations.
targetedonc.com
The DISCUS trial reveals that shorter systemic therapy improves quality of life for advanced urothelial cancer patients, challenging traditional treatment durations.
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#FDANews: The FDA has approved daratumumab and hyaluronidase-fihj (Darzalex Faspro) for the treatment of adult patients with high-risk smoldering multiple myeloma.π£ π: https://t.co/zQ50jjwQiR
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π¨ββοΈAfternoon Watch: Jason S. Starr, DO, discusses the significance of the extrapancreatic neuroendocrine tumor cohort of the phase 3 CABINET trial (NCT03375320) of cabozantinib. π‘ #CancerResearch #OncologyNews π:
targetedonc.com
Jason S. Starr, DO, discusses the significance of the extrapancreatic neuroendocrine tumor cohort of the phase 3 CABINET trial of cabozantinib.
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#ESMO25: Nivolumab plus visugromab showed superior efficacy to placebo and good tolerability in patients with newly diagnosed muscle-invasive bladder cancer, according to GDFATHER-NEO trial results.π‘ π:
targetedonc.com
Nivolumab combined with visugromab demonstrates enhanced efficacy and tolerability in treating muscle-invasive bladder cancer, outperforming placebo in a recent trial.
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π Results from the phase 1 RaDD trial radiotherapy added to immunotherapy enhanced responses, demonstrated manageable safety, and was informed by T-cell dysregulation in patients with B-cell lymphomas. βοΈ Read the full trial results here:
targetedonc.com
A phase 1 trial reveals that combining radiotherapy with immunotherapy enhances response rates in B-cell lymphomas while maintaining manageable safety profiles.
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π£ FDA News: The FDA has granted orphan drug designation to the acute myeloid leukemia treatment candidate M2T-CD33 (LTI-214), signaling a potential entrance for a novel, differentiated therapeutic approach to this aggressive disease.π‘ π: https://t.co/UcQO0ckjnj
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βοΈMorning Watch: Dr. Michael Soulen discusses the safety and efficacy regarding the novel combined treatment for neuroendocrine tumors that utilizes both systemic chemotherapy and peptide receptor radionuclide therapy at the 2025 NANETS Symposium.π π:
targetedonc.com
A novel treatment combining chemotherapy and PRRT shows promising safety and efficacy for neuroendocrine tumors, with high response rates and ongoing trials.
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π‘ EDGE-Gastric trial: The combination of domvanalimab and zimberelimab showed a 59% objective response rate in advanced HER2-negative gastroesophageal cancer patients, with a median overall survival of 26.7 months. π:
targetedonc.com
The EDGE-Gastric trial reveals promising results for domvanalimab and zimberelimab in treating advanced gastric cancer, showcasing durable efficacy and manageable safety.
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π‘ TRIMM-2 Study: Talquetamab and daratumumab combination achieved an 82.4% overall response rate in relapsed/refractory multiple myeloma patients, with a median PFS of 21.2 months. Read the full trial results here:
targetedonc.com
Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted precision medicine strategies.
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#ESMO2025: A novel combination therapy shows promise for preserving kidneys in high-risk upper tract urothelial carcinoma, challenging traditional treatment methods. #Kidney #UrothelialCarcinoma
targetedonc.com
A novel combination therapy shows promise for preserving kidneys in high-risk upper tract urothelial carcinoma, challenging traditional treatment methods.
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πΉ WATCH: Experts explore a novel combined therapy for liver-dominant #neuroendocrine tumors, enhancing treatment durability with chemotherapy and PRRT. #NANETS2025
targetedonc.com
Experts explore a novel combined therapy for liver-dominant neuroendocrine tumors, enhancing treatment durability with chemotherapy and PRRT.
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πΉ WATCH: Dr. Jonathan Strosberg discusses the promising results of the ALPHAMEDIX-02 trial, evaluating a new therapy for advanced neuroendocrine tumors. #NANETS2025
targetedonc.com
Dr. Jonathan Strosberg discusses the promising results of the ALPHAMEDIX-02 trial, evaluating a new therapy for advanced neuroendocrine tumors.
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