Tomasz
@t_czer_jea
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Postdoc, SciLifeLab
Dresden, Germany
Joined March 2019
Effects of lipid membranes on RNA catalytic activity and stability https://t.co/hWSKN0QUTJ
#biorxiv_synbio
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🔥RNA & lipids in action 🧬! Our latest study, featuring @t_czer_jea as lead author, reveals how lipid membranes affect the activity of catalytic RNAs. @BCUBE_TUDresden @James_Saenz
Effects of lipid membranes on RNA catalytic activity and stability https://t.co/hWSKN0QUTJ
#biorxiv_synbio
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@anh_nhn_ 's manuscript is now published in @BiophysJ 🥳"Varying the position of phospholipid acyl chain unsaturation modulates hopanoid and sterol ordering": https://t.co/iBAy9xPZ0p
@BCUBE_TUDresden
cell.com
The cell membrane must balance mechanical stability with fluidity to function as both a barrier and an organizational platform. Key to this balance is the ordering of hydrocarbon chains and the...
Time to dive in the world of bacterial membranes 🦠, and #hopanoids! In our new preprint https://t.co/xZi4mK8XeV we show how subtle changes to phospholipid structure can alter hopanoid (or sterol)-lipid interactions with big consequences for the membrane and the cell! #lipidtime
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We are all super proud of @anh_nhn_ for winning the 🎉 Flash Talk Award 🎉 in #Graz at the @DGesFett International Symposium on Microbial Lipids...a real #Sachertorte from Vienna 🥮. Check out the preprint she presented -> https://t.co/kKSLsD8nZc
#lipidtime @BCUBE_TUDresden
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Adapting to cold🥶☃️: Lipidomics of Minimal Cells! Our new study explores how simple organisms like Mycoplasma mycoides & JCVI-Syn3B alter their membrane lipids with temperature change https://t.co/ACyiuLD8zf
@NataliyaSafric @James_Saenz @BCUBE_TUDresden @JCVenterInst #lipidtime
biorxiv.org
All cells are encapsulated by a lipid membrane which facilitates the interaction between life and its environment. How life exploits the diverse mixtures of lipids that dictate membrane property and...
From hot to cold: dissecting lipidome adaptation in the minimal organisms Mycoplasma mycoides and JCVI-Syn3B https://t.co/7oJwLtxDsK
#bioRxiv
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Time to dive in the world of bacterial membranes 🦠, and #hopanoids! In our new preprint https://t.co/xZi4mK8XeV we show how subtle changes to phospholipid structure can alter hopanoid (or sterol)-lipid interactions with big consequences for the membrane and the cell! #lipidtime
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If you fuse fluid vesicles with one that has gel domains, would you dissolve these domains? Yes. Here is how: https://t.co/Ok8uQTfeZm
@BiophysJ Thanks Rafa Cavalcanti @BiophysLira Ella Ewins & Karin Riske @MpiciPotsdam @unifesp With the vesicles you can decorate a Christmas🎄🤩
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Job alert. Our lab is hiring! We are looking for a PhD student or Postdoc to work on #diatom biomineralization using biochemical, molecular genetic and cell biology tools. 🔬🧬
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Let's talk about the 2016 University of Hawaii-Manoa lab explosion as a case study in #LabSafety practices. A few of the photos will be marked sensitive because a postdoc lost an arm in the explosion & there's blood at the scene. This story is a warning to all researchers.
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New paper alert! We have developed a method to coat microscopic beads with natural membranes, in order to study protein-protein interactions with optical tweezers: https://t.co/1R7AGeuqBd Led by Sudheer K. Cheppali! @ACS_AMI
pubs.acs.org
Multiple biological and pathological processes, such as signaling, cell–cell communication, and infection by various viruses, occur at the plasma membrane. The eukaryotic plasma membrane is made up...
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Exciting to share the 2nd paper this week - they come in bursts;) #Mathias in collab with Dorna from Deber lab @UoftB and @LabSaenz looked at the interplay of cholesterol, a CFTR hairpin and lumacaftor #BBA
https://t.co/WjEb1HWVRT
@BCUBE_TUDresden also with support by @mukoinfo
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Very excited to share the preprint of our new results in collaboration with Santen lab (@Saar_Uni). We show Dynein and Kinesins can drive bidirectional vesicle transport in vitro with directional reversals, without regulators.
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🎉 Congratulations 🎉 to @t_czer_jea for defending his PhD thesis! Tomasz revealed how lipids can regulate RNA activity through sequence-dependent interactions. @digsbb @tudresden_de @BCUBE_TUDresden
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What a great conference! Big thanks to organizers, presenters (both talks and posters), and all participants for making this meeting as stimulating and enjoyable as possible! @emergenceoflife
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Why make many lipids? The importance of some lipids is only apparent under certain conditions. In our paper, @tookmaniac shows how hopanoids can help bacteria to survive variable soil conditions, despite being dispensable in plant symbioses. https://t.co/u1wPxE19vN
@Ra_MicroSci
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Our work just got published in @NatureComms. We developed a dual designer-recombinase system that efficiently corrects a 140 kb inversion frequently found in patients with severe Hemophilia A. 1/11 @BuchholzLab_TUD @TakebeLab @tudresden_de @Medizin_TUD
https://t.co/JV5cFIlODQ
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Modeling the Minimal Cell - now lipids are included, happy we could contribute! Congratulations to Zan Luthey-Schulten and Zane Thornburg @UofIllinois for leading this nice collaboration with @JCVenterInst and @BCUBE_TUDresden @tudresden_de
cell.com
A kinetic model for a minimal bacterial cell offers quantitative insight into how the cell balances processes from metabolism to gene expression to growth.
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Our latest manuscript "Lipid membranes modulate the activity of RNA through sequence-dependent interactions" is... 🎉🎊 published 🎊🎉!! https://t.co/apkBfP0dB5
@t_czer_jea @James_Saenz @PNASNews @VolkswagenSt @BMBF_Bund @SimonsFdn @BCUBE_TUDresden
pnas.org
RNA is a ubiquitous biomolecule that can serve as both catalyst and information carrier. Understanding how RNA bioactivity is controlled is crucial...
Lipids and RNA have something in common: they are essential for life, and most people don’t want to work on them. Now we show that everyone’s least favorite biomolecules actually interact in a useful way. How? https://t.co/EkOCjo8TKP
@t_czer_jea @James_Saenz
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