We are proud to be one of the 13 projects funded by the NIH Autism Data Science Initiative. Our project: "Elucidating the Interplay of Genes and Environment in Autism Using Genomic and Exposure Data from Large Populations" 🧵 https://t.co/7gp6gBNYgn

Now that the white stripes are in the Rock n Roll hall of fame, you are officially a full professor

Jim convinced me to expand my genetic studies from a singular focus on autism to a more trans-diagnostic approach, something that is now a defining aspect of my work. RIP Jim

Hot off the press @NeuroCellPress "From variants to mechanisms: Neurogenomics in the post-GWAS era" Genetic architect -> biological mech for ASD/SCZ/AD Major effort led by MSTP student Michael Margolis + great collab w/ @MichaelZiller5 & @WrayNaomi https://t.co/Iskl55oEAK

Did he mean EST or PST?

It's a good thing autism genes have so much functional convergence. Because if actually they had ALOT of divergence, there is no way we could tell in a study of 9 genes.

journal covers are making a comeback

This but for Nobel Laureates 🤣

Check out our new resource paper @CellStemCell, where we present a brain organoid atlas of human neurodevelopmental disorders. Surprising was that nearly all patients had abnormal organoids. The challenge was aligning defects to clinical. https://t.co/0YtGTd4Dwb

Our daily reminder that clinical genetics is not just for intellectual disability and for the occasional rare disease that some octagenerian doctor can diagnose from their clinical eval. Adults with common disease need clinical genetic testing.

Choose your weapon

What fraction of trick or treaters are going to be wearing black chucks? -1% -5% -10% ->10%

Neuroscientists on Halloween

Ohtani received IV fluids after game 3. Cyclists be like:

Please RT: We are recruiting a postdoc in statistical genetics for a project in my lab on genes and environment in autism

Check out the @n_lorem 2025 Nano-rare Patient Colloquium held @biogen last week. So many amazing families and patients benefiting from #ASOs for rare conditions. https://t.co/CNm235bGgW.

Next Pixar movie just dropped…

Rare diseases are not just associated with autism and schizophrenia. They part of the polygenic basis of ALL complex traits, including mood disorders, adhd, ptsd

I would argue yes! But the paradigm really started shifting around 2010

I really love this paper on rare disease cases found within common metabolic, immune and cardiovascular disease. Is it a paradigm shift?

I did not realize how much of a genius Ray Parker Jr. was until I scheduled a gig for Halloween night