Out now in @Chem_CP , we collaborate with @piel_lab to discover a prenyltransferase+terpene cyclase fusion enzyme that modifies Trp residues in RiPPs to yield complex steroid-like scaffolds! Congrats to @HubrichFlorian, @sanathrajkk0 for leading this!🎉 https://t.co/2TGkSQzbfq

Congrats to @HubrichFlorian & @sanathrajkk0 for this exciting story finally being published. Thanks for the fruitful collaboration with @chekanlab. If you are interested in the chemical space of #RiPP #biosynthetic #enyzmes and #isoprenoids, click here: https://t.co/LGXC9ier8Z

We are super proud of @MrMunsterberg for winning the #DiscoveryAward2024 at the #ICNPR2024 last week! Very well deserved, Johannes. Keep following us to stay tuned for updates on his amazing research!

We are having a great time being @ETH_DBIOL symposium in #Davos again. Listening to fantastic talks, discussing science on posters and of course socializing with peers.

Our review is part of a special issue on Biocatalysis and Biotransformation, edited by Ikuro Abe and Taifo Mahmud. Don't forget to check out the other articles in the collection at https://t.co/mV8VMODlgy ... and stay tuned because new articles are still being released.

The review summarizes advancements in the field during the past two years - which are numerous, considering the rapid pace and the talented groups working on RiPPs.

Are you interested in peptide natural products and especially post-translationally modified peptides? Check out this review by our @danirichterfl on ribosomally synthesized and post-translationally modified peptides (RiPPs) here: https://t.co/KSYKx9xm8t

In beautiful biochemical work they show the azole-dependent installation of dehydroamino acids here: https://t.co/TczUzfpvuY

Check out our recent News & Views by Anna Vagstad and @danirichterfl highlighting an article by @Nairlab_UIUC. Unusual LanM architecture enables the biosynthesis of dehydrazoles https://t.co/ANMkndi9vU #RiPPs #NaturalProducts #Enzyme

Thank you @ScienceMagazine for highlighting our paper here!

...and last but not least, make sure to not miss this amazing piece of research also published @ScienceMagazine by @HelgeBode_Lab and covers the #reprogramming of #NRPS for cool new #peptides. What a day in #naturalproductresearch! https://t.co/5OZ8eOjKpT

For a brief summary, make sure to also check out the 🧵written by @Mathijsfjm: https://t.co/PV5rpRFQL0

We are super proud of @Mathijsfjm, Stefan, @clarachepkirui7, @hannah_minas and of course all other co-authors for bringing this story together. Also a big thank you for the fruitful collaboration with everyone from the labs of Birgit Piechulla and Allison Walker.

An amazing team effort brings us one step closer cracking the nut of #polyketidesynthase reprogramming. In our new paper published in @ScienceMagazine, we shed light on #Engineering these multimodular assembly lines used for #naturalproduct #biosynthesis. https://t.co/LznO4Wqi36

Congrats to @AnnaVagstad bringing this amazing story to the finish line! Thank you to everyone involved from @BroderickLabFeS for the fantastic collaboration! If you are interested in the enzymatic mechanism of peptide epimerization by rSAM, make sure to read it.👇

We are very proud of @Mathijsfjm for starting his own research group and even more exciting to see what amazing research will come from his lab! Stay tuned for exciting projects 👨‍🔬🧫⚗️

We are very proud of @aefraley for being one of these professor! Stay tuned for amazing research coming from her lab👩‍🏫👩‍🔬🧫⚗️

Exciting news! Did Acidobacteria also pop-up in your MAGs? In our new paper we identify sponge-type polyketides from this unusual phylum: https://t.co/JZFs0xw8nm Have a read for more details. We are excited to see where else we can find Acidos!

Winter wonderland has started in Switzerland! Snowy greetings from the Pielis ❄️☃️

Congrats to @HubrichFlorian for his amazing talk on RiPP modifying enzymes! #VAAMNP @Helmholtz_HIPS